銆€婀栧崡甯寖澶у(xu茅)纰╁＋鐮旂┒鐢熷叆瀛�(xu茅)鑰冭│鑷懡椤岀鐩€冭│澶х侗

鑰冭│绉戠洰浠ｇ⒓锛�                    鑰冭│绉戠洰鍚嶇ū锛� 鍒嗗瓙鐢熺墿瀛�(xu茅)

涓€銆佽€冭│鍏�(n猫i)瀹瑰強瑕侀粸(di菐n)

1銆佸垎瀛愮敓鐗╁(xu茅)鐨勫熀鏈蹇�銆佺爺绌�?j墨)?n猫i)瀹硅垏鍚勫(xu茅)绉戜箣闁撶殑闂�(gu膩n)绯诲強鍏剁櫦(f膩)灞曡定鍕�(sh矛)

鑰冭│鍏�(n猫i)瀹癸細鍒嗗瓙鐢熺墿瀛�(xu茅)鐨勫熀鏈蹇�銆佺爺绌�?j墨)?n猫i)瀹硅垏鍚勫(xu茅)绉戜箣闁撶殑闂�(gu膩n)绯诲強鍏剁櫦(f膩)灞曡定鍕�(sh矛)锛�

鑰冭│瑕侀粸(di菐n)锛�

(1) 鐞嗚В鍒嗗瓙鐢熺墿瀛�(xu茅)鐨勬蹇碉紝鐔熸倝鍒嗗瓙鐢熺墿瀛�(xu茅)鐨勭爺绌�?j墨)?n猫i)瀹逛互鍙婇棞(gu膩n)閸垫蹇电殑鑻辨枃鍚嶇ū锛涚啛鎮夊垎瀛愮敓鐗╁(xu茅)鐨勪富瑕佹敮鏌卞(xu茅)绉戝強鑸囧悇瀛�(xu茅)绉戜箣闁撶殑闂�(gu膩n)绯汇€�

(2) 鐔熸倝鍒嗗瓙鐢熺墿瀛�(xu茅)鐨勭櫦(f膩)灞曟绋嬪強鐔熸倝妯�(bi膩o)蹇楁€х殑鐮旂┒瀵�(sh铆)渚�銆�

(3) 浜嗚В鍒嗗瓙鐢熺墿瀛�(xu茅)鐨勬渶鏂扮爺绌堕€�(j矛n)灞曞強鐧�(f膩)灞曡定鍕�(sh矛)銆�

2銆佹牳閰哥殑绲�(ji茅)妲�(g貌u)鑸囧姛鑳�

鑰冭│鍏�(n猫i)瀹�:

绱�(x矛)鑳炲収(n猫i)閬哄偝鐗╄唱(zh矛)鐨勬蹇点€佺窗(x矛)鑳炲収(n猫i)鏍搁吀鐨勫垎椤炪€佺祫鎴�銆佸寲瀛�(xu茅)鎬ц唱(zh矛)銆佺祼(ji茅)妲�(g貌u)鍙婂堡娆�;DNA鐨勯珮绱�(j铆)绲�(ji茅)妲�(g貌u)鑸囧姛鑳�锛孯NA鐨勭祼(ji茅)妲�(g貌u)鑸囧姛鑳�;鏍搁吀鐨勮畩鎬с€佸京(f霉)鎬ц垏闆滀氦;

鑰冭│瑕侀粸(di菐n):

(1)鎺屾彙閬哄偝鐗╄唱(zh矛)鐨勬蹇靛強鍒嗛銆傜啛绶存帉鎻℃牳閰哥殑鍖栧(xu茅)绲勬垚銆佷竴绱�(j铆)绲�(ji茅)妲�(g貌u)銆佷簩绱�(j铆)绲�(ji茅)妲�(g貌u)鍜岄珮绱�(j铆)绲�(ji茅)妲�(g貌u);鎺屾彙鐪熸牳鐢熺墿鏌撹壊楂旂殑鍖栧(xu茅)绲勬垚銆佺祫瑁濆堡娆″強鍏堕珮绱�(j铆)绲�(ji茅)妲�(g貌u)鍜屽姛鑳�銆�

(2)鐔熺反鎺屾彙RNA鐨勭祼(ji茅)妲�(g貌u)鐗归粸(di菐n)锛岃垏DNA鐨勫崁(q奴)鍒ュ強RNA鐨勫垎椤炲拰澶氭ǎ鎬�銆�

(3)鐔熺反鎺屾彙鏍搁吀鐨勮畩鎬�銆佸京(f霉)鎬ц垏闆滀氦銆�

3銆佸熀鍥犺垏鍩哄洜绲勭殑绲�(ji茅)妲�(g貌u)鑸囧姛鑳�

鑰冭│鍏�(n猫i)瀹�:

鍩哄洜鑸囧熀鍥犵祫鐨勬蹇�銆佺湡鏍哥敓鐗╁熀鍥犵祫鐨勫ぇ灏忓強鍏惰垏C鍊肩殑闂�(gu膩n)绯�;鐥呮瘨鍙婂叾鍩哄洜绲勶紱绱�(x矛)鑿屽熀鍥犵祫锛涚湡鏍哥敓鐗╁熀鍥犵祫;鍚屾簮閲嶇祫鍜屼綅榛�(di菐n)鐗圭暟鎬ч噸绲�;杞�(zhu菐n)搴т綔鐢ㄥ拰閫嗚綁(zhu菐n)閷勮綁(zhu菐n)搴у瓙銆�

鑰冭│瑕侀粸(di菐n):

(1) 鐔熺反鎺屾彙鍩哄洜鑸囧熀鍥犵祫鐨勬蹇�锛岀啛鎮夌湡鏍哥敓鐗╁熀鍥犵祫鐨勫ぇ灏忓強鍏惰垏C鍊肩殑闂�(gu膩n)绯�銆�

(2) 鐔熺反鎺屾彙绱�(x矛)鑿屽熀鍥犵祫鍜岀湡鏍哥敓鐗╁熀鍥犵祫鐨勭祼(ji茅)妲�(g貌u)銆佺壒榛�(di菐n)銆�

(3)鐔熸倝绶氱矑楂斿拰钁夌稜楂斿熀鍥犲強鍏剁祼(ji茅)妲�(g貌u)鐗瑰緛銆�

(4)浜嗚В浜洪鍩哄洜绲�銆佽泲鐧界祫鍙婄敓鐗╀俊鎭(xu茅)銆�

(5)鐔熺反鎺屾彙鍚屾簮閲嶇祫鐨勫垎瀛愭ā寮忋€佸熀鏈蹇佃垏閰剁郴銆�

(6)鎺屾彙鍣弻楂斿拰澶ц吀妗胯弻浣嶉粸(di菐n)鐗圭暟鎬ч噸绲勩€�

(7)鐔熺反鎺屾彙杞�(zhu菐n)搴у瓙鐨勬蹇�銆佸垎椤炲強杞�(zhu菐n)搴ф(j墨)鐞嗗拰鐗瑰緛锛屾帉鎻￠€嗚綁(zhu菐n)閷勮綁(zhu菐n)搴у瓙鐨勭祼(ji茅)妲�(g貌u)鐗归粸(di菐n)銆佹(j墨)鐞�;鐞嗚В杞�(zhu菐n)搴у拰閫嗚綁(zhu菐n)閷勮綁(zhu菐n)搴х殑閬哄偝鏁堟噳(y墨ng)鍜岀敓鐗╁(xu茅)鎰忕京銆�

4銆丏NA寰�(f霉)鍒躲€佽綁(zhu菐n)閷勮垏杞�(zhu菐n)閷勫悗鐨勫壀鎺ヨ垏鍔犲伐

鑰冭│鍏�(n猫i)瀹癸細

DNA 寰�(f霉)鍒舵杩�;澶ц吀妗胯弻DNA寰�(f霉)鍒跺強鍏惰(di脿o)鎺�銆佺湡鏍哥敓鐗〥NA寰�(f霉)鍒跺強鍏惰(di脿o)鎺�;杞�(zhu菐n)閷勭殑姒傝堪;绱�(x矛)鑿屽強鐪熸牳鐢熺墿鐨凴NA鑱氬悎閰跺強鍏惰綁(zhu菐n)閷�;鍘熸牳鍩哄洜杞�(zhu菐n)閷勫暉鍕�(d貌ng)瀛愮殑绲�(ji茅)妲�(g貌u)鐗瑰緛 鍙婂叾杞�(zhu菐n)閷勭敘(ch菐n)鐗╃殑瀹氫綅;鐪熸牳鍩哄洜杞�(zhu菐n)閷勫暉鍕�(d貌ng)瀛愮殑绲�(ji茅)妲�(g貌u)鐗瑰緛鍙婂叾杞�(zhu菐n)閷勮捣濮嬪京(f霉)鍚堢墿锛汻NA鐨勮綁(zhu菐n)閷勮(di脿o)鎺у強杞�(zhu菐n)閷勭殑鎶戝埗锛涘師鏍哥敓鐗╄垏鐪熸牳鐢熺墿RNA杞�(zhu菐n)閷勫悗鐨勫姞宸ラ亷(gu貌)绋�銆�

鑰冭│瑕侀粸(di菐n):

(1)鐔熸倝鍜屾帉鎻NA寰�(f霉)鍒剁殑鍩烘湰閬�(gu貌)绋�銆佸熀鏈蹇�銆�

(2)鐔熺反鎺屾彙澶ц吀妗胯弻DNA寰�(f霉)鍒惰捣濮嬩綅榛�(di菐n)鐨勭祼(ji茅)妲�(g貌u)鐗瑰緛锛屾湁闂�(gu膩n)鐨勯叾鍜岃泲鐧借唱(zh矛)鐨勪綔鐢�锛屾帉鎻″京(f霉)鍒剁殑鍩烘湰閬�(gu貌)绋�銆�

(3)鐔熺反鎺屾彙鐪熸牳鐢熺墿DNA寰�(f霉)鍒剁殑閰剁郴鍙婂叾浣滅敤锛屾帉鎻＄绮掔殑姒傚康鍙婂京(f霉)鍒舵(j墨)鍒躲€�

(4)鎺屾彙鍘熸牳鑸囩湡鏍歌綁(zhu菐n)閷勭殑杞�(zhu菐n)閷勭壒榛�(di菐n)銆佽綁(zhu菐n)閷勯亷(gu貌)绋嬪強宸暟銆�

(5)鐔熺反鍘熸牳鐢熺墿銆佺湡鏍哥敓鐗㏑NA鑱氬悎閰剁郴鍜屽暉鍕�(d貌ng)瀛愮殑绲�(ji茅)妲�(g貌u)鐗瑰緛銆�

(6)鐔熺反鎺屾彙鐪熸牳鐢熺墿涓夐鍩哄洜鐨勫暉鍕�(d貌ng)瀛愮殑绲�(ji茅)妲�(g貌u)鐗瑰緛鍜岃綁(zhu菐n)閷勮捣濮嬪京(f霉)鍚堢墿鐨勫舰鎴愬拰杞�(zhu菐n)閷勭敘(ch菐n)鐗�銆�

(7)鎺屾彙杞�(zhu菐n)閷勭殑闋嗗紡浣滅敤鍏冧欢鍜屽弽寮忎綔鐢ㄥ洜瀛愮殑杞�(zhu菐n)閷勮(di脿o)鎺�銆�

(8)鐔熺反鎺屾彙鍘熸牳鐢熺墿鍜岀湡鏍哥敓鐗㏑NA鐨勮綁(zhu菐n)閷勫悗鍔犲伐閬�(gu貌)绋�锛涙帉鎻NA鐨勮嚜鎴戝壀鎺�锛涢伕鎿囨€у壀鎺�锛汻NA鐨勭法杓�銆�

5銆丏NA鐨勬悕鍌�銆佷慨寰�(f霉)鍜屽熀鍥犵獊璁�

鑰冭│鍏�(n猫i)瀹癸細

DNA鎼嶅偡鐨勬蹇�銆佸洜绱犲拰椤炲瀷锛汥NA淇京(f霉)鐨勯鍨�銆佹蹇碉紱鍩哄洜绐佽畩銆�

鑰冭│瑕侀粸(di菐n):

(1)鎺屾彙DNA鎼嶅偡鐨勬蹇点€佸紩璧锋悕鍌风殑鍥犵礌銆佸垎椤炲拰淇京(f霉)椤炲瀷銆�

(2)鎺屾彙鍩哄洜绐佽畩鐨勯鍨嬪拰瑾樿畩鍔戠殑浣滅敤姗�(j墨)鐞�銆�

(3)鐔熸倝鍩哄洜绐佽畩鐨勫悗鏋�銆�

6.铔嬬櫧璩�(zh矛)鐨勭敓鐗╁悎鎴�-缈昏銆�

鑰冭│鍏�(n猫i)瀹癸細

閬哄偝瀵嗙⒓銆佸瘑纰煎瓙鐨勭啊(ji菐n)骞舵€у拰璁婂伓鎬�銆侀€氱敤鎬у拰璁婄暟鎬�;鍙畝妗嗚垏閲嶇枈鍩哄洜;铔嬬櫧璩�(zh矛)鍚堟垚鐨勫垎瀛愬熀绀�(ch菙)锛屽悎鎴愰亷(gu貌)绋嬭垏瑾�(di脿o)鎺�;铔嬬櫧璩�(zh矛)鐨勮綁(zhu菐n)閬�(y霉n);铔嬬櫧璩�(zh矛)鐨勪慨椋捐垏鎶樼枈銆�

鑰冭│瑕侀粸(di菐n):

(1)浜嗚В瀵嗙⒓鐨勫熀鏈壒寰�锛屾帉鎻″瘑纰煎瓙鐨勭啊(ji菐n)骞舵€у拰璁婂伓鎬с€侀€氱敤鎬у拰璁婄暟鍨�銆�

(2)鎺屾彙璧峰瀵嗙⒓鍜岀祩姝㈠瘑纰硷紝鐔熺反鎺屾彙铔嬬櫧璩�(zh矛)鐨勭炕璀亷(gu貌)绋嬪強铔嬬櫧璩�(zh矛)鐨勫悎鎴愯(di脿o)鎺�銆�

(3) 鐔熸倝铔嬬櫧璩�(zh矛)鐨勪慨椋俱€佹姌鐤婂強铔嬬櫧璩�(zh矛)鍚堟垚鍚庣殑閬�(y霉n)杓�銆�

7.鍩哄洜琛ㄩ仈(d谩)鑸囪(di脿o)鎺�

鑰冭│鍏�(n猫i)瀹癸細

鍘熸牳鍩哄洜琛ㄩ仈(d谩)鑸囪(di脿o)鎺�锛涙銆佽矤(f霉)瑾�(di脿o)鎺х郴绲�(t菕ng)锛涗钩绯栨搷绺卞瓙銆佽壊姘ㄩ吀鎿嶇副瀛�銆侀樋鎷変集绯栨搷绺卞瓙銆佸崐涔崇硸鎿嶇副瀛�銆佺祫姘ㄩ吀鎿嶇副瀛愶紱绱�(x矛)鑿岀殑鎳�(y墨ng)鎬ュ弽鎳�(y墨ng)銆傜湡鏍哥窗(x矛)鑳炲熀鍥犺〃閬�(d谩)瑾�(di脿o)鎺х殑鐗归粸(di菐n)鑸囦笉鍚屽堡娆★紱鐪熸牳鐢熺墿杞�(zhu菐n)閷勮(di脿o)鎺х殑鍚勭ó闋嗗紡浣滅敤鍏冧欢鍜屽弽寮忎綔鐢ㄥ洜瀛�銆�

鑰冭│瑕侀粸(di菐n):

(1)鎺屾彙鍘熸牳鍩哄洜琛ㄩ仈(d谩)瑾�(di脿o)鎺х殑鐗归粸(di菐n)锛岀啛绶存帉鎻′钩绯栨搷绺卞瓙瀛�(xu茅)瑾�(shu艒)鍙婅(di脿o)鎺ф(j墨)鐞�銆傜啛鎮夊叾瀹冨悇鎿嶇副瀛愮殑瑾�(di脿o)鎺ф(j墨)鍒躲€�

(2)鎺屾彙鍩哄洜琛ㄩ仈(d谩)瑾�(di脿o)鎺х殑鍩烘湰姒傚康锛屾銆佽矤(f霉)瑾�(di脿o)鎺х郴绲�(t菕ng)銆�

(3)鎺屾彙鐪熸牳鍩哄洜琛ㄩ仈(d谩)鐨勪笉鍚屽堡娆″強鍏惰(di脿o)鎺�;鍚勭ó闋嗗紡浣滅敤鍏冧欢鐨勬蹇靛拰鐗归粸(di菐n)浠ュ強鍙嶅紡浣滅敤鍥犲瓙鐨勯鍨嬭垏绲�(ji茅)妲�(g貌u)銆�

8.鍩哄洜宸ョ▼鍜岃泲鐧借唱(zh矛)宸ョ▼

鑰冭│鍏�(n猫i)瀹癸細

DNA鍏嬮殕鐨勫熀鏈師鐞嗭紱鍏稿瀷鐨勯伜鍌冲伐绋嬫妧琛�(sh霉)锛涜級楂旀敼閫犲師鐞�锛涘熀鍥犱締(l谩i)婧愩€佷汉椤炲熀鍥犲伐绋嬭▓(j矛)鍔冨強鏍哥畻闋嗗簭鍒嗘瀽锛汻NA鍜孌NA鐨勬脯(c猫)搴忔柟娉曞強鍏堕亷(gu貌)绋�锛涘熀鍥犵殑鍒嗛洟銆佸悎鎴愬拰娓�(c猫)搴�锛涜泲鐧借唱(zh矛)宸ョ▼銆�

鑰冭│瑕侀粸(di菐n):

(1)鐞嗚ВDNA鍏嬮殕鐨勫熀鏈師鐞�銆�

(2)鎺屾彙鍚勭ó姘村钩涓婄殑鍩哄洜琛ㄩ仈(d谩)瑾�(di脿o)鎺�銆�

(3)浜嗚В浜洪鍩哄洜绲勮▓(j矛)鍔冨強鏍哥畻搴忓垪鍒嗘瀽銆�

(4)鎺屾彙RNA鍜孌NA鐨勬脯(c猫)搴忔柟娉曞強鍏堕亷(gu貌)绋嬨€�

(5)浜嗚В铔嬬櫧璩�(zh矛)宸ョ▼鐨勯€�(j矛n)灞�銆�

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