鍙嬫儏鎻愮ず锛氭湰绔欐彁渚涘叏鍦�(gu贸)400澶氭墍楂樼瓑闄㈡牎鎷涙敹纰╁＋銆佸崥澹爺绌剁敓鍏ュ(xu茅)鑰冭│姝峰勾鑰冪爺鐪熼銆佽€冨崥鐪熼銆佺瓟妗�锛岄儴鍒嗗(xu茅)鏍℃洿鏂拌嚦2012骞达紝2013骞�锛涘潎鎻愪緵鏀惰不(f猫i)涓嬭級銆� 涓嬭級娴佺▼锛� 鑰冪爺鐪熼 榛�(di菐n)鎿娾€�鑰冪爺瑭﹀嵎鈥濃€濅笅杓�; 鑰冨崥鐪熼 榛�(di菐n)鎿娾€�鑰冨崥瑭﹀嵎搴�鈥� 涓嬭級
娴欐睙杈�(n贸ng)鏋楀ぇ瀛�(xu茅)纰╁＋鐮旂┒鐢熷叆瀛�(xu茅)鑰冭│
鐢熺墿鍖栧(xu茅)涓€鑰冭│澶х侗
鏈€婄敓鐗╁寲瀛�(xu茅)銆嬭€冭│澶х侗閬╃敤浜庢禉姹熻静(n贸ng)鏋楀ぇ瀛�(xu茅)鐢熺墿瀛�(xu茅)銆佹灄瀛�(xu茅)纰╁＋瀛�(xu茅)浣嶇殑鐮旂┒鐢熷叆瀛�(xu茅)鑰冭│銆備富瑕佸収(n猫i)瀹瑰寘鎷敓鐗╁ぇ鍒嗗瓙浠ュ強鍏朵粬鐢熺墿鍒嗗瓙鐨勭祼(ji茅)妲�(g貌u)銆佹€ц唱(zh矛)鍜屽姛鑳�锛涚敓鐗╅珨鍏�(n猫i)涓昏鐨勭墿璩�(zh矛)浠ｈ瑵鍜岃兘閲忚綁(zhu菐n)鍖栵紱鐢熺墿閬哄偝淇℃伅鍌抽仦鐨勫寲瀛�(xu茅)鍩虹(ch菙)锛涘熀鍥犺〃閬�(d谩)瑾�(di脿o)鎺у拰鍩哄洜宸ョ▼鍩烘湰鐞嗚珫绛�銆傝姹傚(xu茅)鐢熸瘮杓冪郴绲�(t菕ng)鍦扮悊瑙ｅ拰鎺屾彙鐢熺墿鍖栧(xu茅)鐨勫熀鏈蹇靛拰鍩烘湰鐞嗚珫锛屾帉鎻″悇椤炵敓鍖栫墿璩�(zh矛)鐨勭祼(ji茅)妲�(g貌u)銆佹€ц唱(zh矛)鍜屽姛鑳藉強鍏跺悎鎴愪唬璎濆拰鍒嗚В浠ｈ瑵鐨勫熀鏈€斿緫鍙婅(di脿o)鎺ф柟娉�锛岀悊瑙ｅ熀鍥犺〃閬�(d谩)瑾�(di脿o)鎺у拰鍩哄洜宸ョ▼鐨勫熀鏈悊璜�锛岃兘缍滃悎閬�(y霉n)鐢ㄦ墍瀛�(xu茅)鐨勭煡璀�(sh铆)鍒嗘瀽鍟忛鍜岃В姹哄晱椤�銆傝│鍗锋豢鍒�150鍒嗭紝鑰冭│鏅�(sh铆)闁�180鍒嗛悩銆�
涓€銆� 鑰冭│鍏�(n猫i)瀹�
1 鏍搁吀鐨勭祼(ji茅)妲�(g貌u)鑸囧姛鑳�
銆€銆€鏍搁吀鐨勭敓鐗╁(xu茅)鍔熻兘锛涙牳閰哥殑绋鍜屽垎甯�锛涙牳閰哥殑鍖栧(xu茅)绲勬垚
銆€銆€DNA鐨勫垎瀛愮祼(ji茅)妲�(g貌u)锛汻NA鐨勫垎瀛愮祼(ji茅)妲�(g貌u)
銆€銆€鏍搁吀鐨勪竴鑸€ц唱(zh矛)锛涙牳閰哥殑绱鍚告敹鎬ц唱(zh矛)锛涙牳閰哥殑璁婃€�銆佸京(f霉)鎬у拰鍒嗗瓙闆滀氦
銆€ 铔嬬櫧璩�(zh矛)姘ㄥ熀閰哥殑绲�(ji茅)妲�(g貌u)鍙婂垎椤�锛涙皑鍩洪吀鐨勭悊鍖栨€ц唱(zh矛)
銆€銆€鑲藉拰鑲介張鐨勭祼(ji茅)妲�(g貌u)鍙婂懡鍚嶏紱閲嶈鐨勫ぉ鐒跺鑲�
銆€銆€铔嬬櫧璩�(zh矛)鐨勪竴绱�(j铆)绲�(ji茅)妲�(g貌u)锛涜泲鐧借唱(zh矛)鐨勬(g貌u)璞″拰缍寔妲�(g貌u)璞＄殑浣滅敤鍔�锛涜泲鐧借唱(zh矛)鐨勪簩绱�(j铆)绲�(ji茅)妲�(g貌u)锛涜泲鐧借唱(zh矛)鐨勪笁绱�(j铆)绲�(ji茅)妲�(g貌u)锛涜泲鐧借唱(zh矛)鐨勮秴浜岀礆(j铆)绲�(ji茅)妲�(g貌u)鍜岀祼(ji茅)妲�(g貌u)鍩�锛涜泲鐧借唱(zh矛)鐨勫洓绱�(j铆)绲�(ji茅)妲�(g貌u)
銆€銆€铔嬬櫧璩�(zh矛)涓€绱�(j铆)绲�(ji茅)妲�(g貌u)鑸囧姛鑳界殑闂�(gu膩n)绯�锛涚┖闁撶祼(ji茅)妲�(g貌u)鑸囧姛鑳界殑闂�(gu膩n)绯�
銆€銆€铔嬬櫧璩�(zh矛)鐨勭浉灏�(du矛)鍒嗗瓙璩�(zh矛)閲忥紱铔嬬櫧璩�(zh矛)鐨勫叐鎬цВ闆㈠強绛夐浕榛�(di菐n)锛涜泲鐧借唱(zh矛)鐨勮啝楂旀€ц唱(zh矛)锛涜泲鐧借唱(zh矛)鐨勬矇娣€鍙嶆噳(y墨ng)锛涜泲鐧借唱(zh矛)鐨勮畩鎬ц垏寰�(f霉)鎬�锛涜泲鐧借唱(zh矛)鐨勭传澶栧惛鏀惰垏鍛堣壊鍙嶆噳(y墨ng)
銆€銆€铔嬬櫧璩�(zh矛)鍒嗛洟绱斿寲鐨勪竴鑸師鍓囷紱铔嬬櫧璩�(zh矛)鐨勬噳(y墨ng)鐢�
銆€銆€閰剁殑姒傚康锛涢叾鐨勫皥涓€鎬э紱閰剁殑鍖栧(xu茅)鏈唱(zh矛)
銆€銆€閰剁殑鍌寲浣滅敤鑸囧垎瀛愭椿鍖栬兘锛涗腑闁撶敘(ch菐n)鐗╁(xu茅)瑾�锛涢叾鐨勬椿鎬ч儴浣嶅拰蹇呴渶鍩哄湗(tu谩n)锛涜獦灏�(d菐o)濂戝悎瀛�(xu茅)瑾�锛涗娇閰跺叿鏈夐珮鍌寲鏁堢巼鐨勫洜绱�锛涜儼鍑濅钩铔嬬櫧閰剁殑鍌寲姗�(j墨)鐞�锛涢叾鍘熸縺娲�
銆€銆€閰跺弽鎳�(y墨ng)閫熷害鐨勬脯(c猫)閲�锛涢叾婵冨害灏�(du矛)閰朵綔鐢ㄧ殑褰遍熆锛涘簳鐗╂績搴﹀皪(du矛)閰朵綔鐢ㄧ殑褰遍熆鍜岀背姘忔柟绋�锛沺H灏�(du矛)閰朵綔鐢ㄧ殑褰遍熆锛涙韩搴﹀皪(du矛)閰朵綔鐢ㄧ殑褰遍熆锛涙縺娲诲姂灏�(du矛)閰朵綔鐢ㄧ殑褰遍熆锛涙姂鍒跺姂灏�(du矛)閰朵綔鐢ㄧ殑褰遍熆
銆€銆€閰剁殑娲诲姏娓�(c猫)瀹氬強鍒嗛洟鎻愮磾
銆€銆€鐢熺墿楂斿収(n猫i)鐨勮剛椤烇細鑴傝偑閰�銆佽剛鑲拰锠�锛涚７鑴�銆侀灅纾疯剛銆侀灅绯栬剛锛涜喗鍥洪唶鍜岃悳椤�
銆€銆€鐢熺墿鑶滅殑鍖栧(xu茅)绲勬垚锛涚敓鐗╄啘鐨勭祼(ji茅)妲�(g貌u)鈥斺€旀祦鍕�(d貌ng)閼插祵妯″瀷锛涚敓鐗╄啘鐨勫姛鑳�
銆€銆€鐢熺墿楂斿収(n猫i)鐨勭硸椤烇細?ji菐n)缈�?锛涘绯�锛涘?/PRE>
銆€銆€绯栭叺瑙ｏ細绯栭叺瑙ｇ殑姒傚康锛涚硸閰佃В鐨勫寲瀛�(xu茅)姝风▼锛涚硸閰佃В鐨勫寲瀛�(xu茅)瑷�(j矛)閲忚垏鐢熺墿瀛�(xu茅)鎰忕京锛涚硸閰佃В鐨勫叾浠栧簳鐗�锛涗笝閰吀鐨勫幓璺�锛涚硸閰佃В鐨勮(di脿o)鎺�
銆€銆€涓夌晶閰稿惊鐠�(hu谩n)锛氫笝閰吀姘у寲鐐轰箼閰癈oA锛涗笁缇ч吀寰挵(hu谩n)锛涗笁缇ч吀寰挵(hu谩n)鐨勮(di脿o)鎺�锛涗笁缇ч吀寰挵(hu谩n)鐨勭敓鐗╁(xu茅)鎰忕京
銆€銆€纾烽吀鎴婄硸閫斿緫锛氱７閰告垔绯栭€斿緫鐨勭敓鍖栨绋嬶紱纾烽吀鎴婄硸閫斿緫鐨勫寲瀛�(xu茅)瑷�(j矛)閲忚垏鐢熺墿瀛�(xu茅)鎰忕京锛涚７閰告垔绯栭€斿緫鐨勮(di脿o)鎺�
銆€銆€鐢熺墿姘у寲姒傚康锛涚敓鐗╁寲瀛�(xu茅)鍙嶆噳(y墨ng)鐨勮嚜鐢辫兘璁婂寲锛涢珮鑳界７閰稿寲鍚堢墿
銆€銆€闆诲瓙鍌抽仦閺�(鍛煎惛閺�)锛氱窔绮掗珨锛涢浕瀛愬偝閬為張锛涢浕瀛愬偝閬炴姂鍒跺姂
銆€銆€姘у寲纾烽吀鍖栫殑姒傚康鍙婇鍨嬶紱姘у寲纾烽吀鍖栬垏闆诲瓙鍌抽仦鐨勫伓鑱�(li谩n)锛涙哀鍖栫７閰稿寲鐨勬(j墨)鐞嗭紱姘у寲纾烽吀鍖栫殑瑙ｅ伓鑱�(li谩n)鍜屾姂鍒�锛涚窔绮掗珨绌挎绯荤当(t菕ng)锛涜兘鑽�
銆€銆€澶氶厷姘у寲閰剁郴绲�(t菕ng)锛涙姉澹炶閰告哀鍖栭叾绯荤当(t菕ng)锛涢粌绱犺泲鐧芥哀鍖栭叾绯荤当(t菕ng)锛涜秴姘у寲鐗╂鍖栭叾鍜岄亷姘у寲姘叾锛涙鐗╂姉姘版哀鍖栭叾绯荤当(t菕ng)
銆€ 绯栫暟鐢熼€斿緫锛涚硸閰佃В鍜岀硸鐣扮敓鐨勪簰瑁�(b菙)瑾�(di脿o)绡€(ji茅)
銆€銆€鑴傝偑鐨勬秷鍖栧拰鍚告敹锛涚敇娌逛唬璎�锛涜剛鑲吀鐨勬哀鍖�锛涢叜楂斾唬璎濓紱涔欓啗閰稿惊鐠�(hu谩n)
銆€銆€鐢樻补鐨勭敓鐗╁悎鎴�锛涜剛鑲吀鐨勭敓鐗╁悎鎴愶紱涓夐叞鐢樻补鐨勭敓鐗╁悎鎴�锛涜剛鑲唬璎濈殑瑾�(di脿o)绡€(ji茅)
銆€銆€纾疯剛鐨勯檷瑙ｈ垏鐢熺墿鍚堟垚锛涚硸鑴傜殑闄嶈В鑸囩敓鐗╁悎鎴�
8 铔嬬櫧璩�(zh矛)鐨勯叾淇冮檷瑙ｅ拰姘ㄥ熀閰镐唬璎�
銆€銆€铔嬬櫧姘磋В閰�锛涢鐗╀腑铔嬬櫧璩�(zh矛)鐨勬秷鍖栧惛鏀�锛涚窗(x矛)鑳炲収(n猫i)铔嬬櫧璩�(zh矛)闄嶈В
銆€銆€姘ㄥ熀閰哥殑鍒嗚В鑸囪綁(zhu菐n)鍖栵細鑴皑鍩轰綔鐢紱鑴晶鍩轰綔鐢�锛涙皑鍩洪吀闄嶈В鐢�(ch菐n)鐗╃殑鍘诲悜
銆€銆€姘ㄥ熀閰哥殑鐢熺墿鍚堟垚锛氭皑鍩洪吀鐨勫悎鎴愯垏杞�(zhu菐n)姘ㄥ熀浣滅敤锛涘悇鏃忔皑鍩洪吀鐨勫悎鎴�锛涗竴纰冲熀鍦�(tu谩n)浠ｈ瑵
銆€銆€鏍搁吀閰�锛涜劔姘ф牳绯栨牳閰搁叾锛涢檺鍒舵€у収(n猫i)鍒囬叾
銆€銆€鏍歌嫹閰哥殑闄嶈В锛涘槍鍛ょ殑闄嶈В锛涘槯鍟剁殑闄嶈В
銆€銆€鏍哥硸鏍歌嫹閰哥殑鍚堟垚锛涜劔姘ф牳鑻烽吀鍚堟垚
銆€銆€DNA鐨勫京(f霉)鍒�锛涢€嗚綁(zhu菐n)閷勪綔鐢�锛汥NA鐨勬悕鍌�銆佷慨寰�(f霉)鑸囩獊璁�
銆€銆€杞�(zhu菐n)閷�锛汻NA鐨勫京(f霉)鍒�
銆€銆€鏍歌嫹閰稿悎鎴愭姂鍒跺姂锛涜垏DNA妯℃澘绲�(ji茅)鍚堢殑鎶戝埗鍔�锛涗綔鐢ㄤ簬鑱氬悎閰剁殑鎶戝埗鍔�
銆€銆€鍩哄洜宸ョ▼鐨勬蹇�锛涘熀鍥犲伐绋嬬殑鎿嶄綔鎶€琛�(sh霉)锛涘熀鍥犲伐绋嬬殑鎳�(y墨ng)鐢ㄨ垏鍓嶆櫙
銆€銆€mRNA鑸囬伜鍌冲瘑纰硷紱tRNA鐨勭祼(ji茅)妲�(g貌u)鍙婂姛鑳�锛涙牳绯栭珨锛涚炕璀紨鍔╁洜瀛�
銆€銆€铔嬬櫧璩�(zh矛)鐨勫悎鎴愶細姘ㄥ熀閰哥殑娲诲寲锛涜偨閺堝悎鎴愮殑璧峰锛涜偨閺堢殑寤朵几锛涜偨閺堝悎鎴愮殑绲傛鑸囬噵鏀�锛涚湡鏍哥窗(x矛)鑳炶泲鐧借唱(zh矛)鐢熺墿鍚堟垚锛涜泲鐧借唱(zh矛)鐨勭炕璀悗鍔犲伐锛涙姂鍒剁炕璀殑鎶楄弻绱�
銆€銆€铔嬬櫧璩�(zh矛)瀹氫綅锛氬垎娉岃泲鐧�锛涚窔绮掗珨鑸囪憠缍犻珨铔嬬櫧
銆€銆€浠ｈ瑵閫斿緫鐨勭浉浜掕伅(li谩n)绯伙紱浠ｈ瑵瑾�(di脿o)绡€(ji茅)锛涚窗(x矛)鑳炰俊铏�(h脿o)杞�(zhu菐n)灏�(d菐o)锛涘熀鍥犺〃閬�(d谩)瑾�(di脿o)鎺�
浜�銆� 鑰冭│瑕佹眰
1 鏍搁吀
鎺屾彙涓昏鐨勫槍鍛�銆佸槯鍟�銆佹牳鑻�銆佹牳鑻烽吀鐨勭祼(ji茅)妲�(g貌u)銆備簡瑙NA鍜孯NA鍦ㄧ祫鎴愩€佺祼(ji茅)妲�(g貌u)鍜屽姛鑳戒笂鐨勫樊鐣�銆傛帉鎻NA闆欒灪鏃嬫ā鍨嬬殑瑕侀粸(di菐n)锛屼互鍙婃ā鍨嬪湪鐢熺墿瀛�(xu茅)涓婄殑鎰忕京銆傚紕娓呮DNA瓒呰灪鏃嬪舰鎴愰亷绋嬪拰鐗归粸(di菐n)銆傛帉鎻″咕绋鍨婻NA绲�(ji茅)妲�(g貌u)鐗瑰緛銆傛帉鎻℃牳閰歌畩鎬у拰寰�(f霉)鎬ф檪(sh铆)鍙嶆槧鍦ㄥ厜璀滃(xu茅)涓婄殑璁婂寲锛屼互鍙婃牳閰搁洔鍖栧師鐞�銆備簡瑙ｅ咕绋渶甯哥敤鐨勬牳閰哥爺绌舵妧琛�(sh霉)銆�
浜嗚В姘ㄥ熀閰哥殑鍒嗛銆佺祼(ji茅)妲�(g貌u)鍜屼竴浜涢噸瑕佺殑鍖栧(xu茅)鍙嶆噳(y墨ng)浠ュ強涓€浜涘垎鏋愭柟娉�銆傛帉鎻¤偨閸�銆佽泲鐧借唱(zh矛)涓€绱�(j铆)绲�(ji茅)妲�(g貌u)姒傚康锛屽咕绋富瑕佽泲鐧介叾鐨勪綔鐢ㄩ儴浣嶅拰铔嬬櫧璩�(zh矛)姘ㄥ熀閰稿簭鍒楃⒑瀹氱殑鏂规硶銆傛帉鎻-铻烘棆銆乥-鎶樼枈鐨勭祼(ji茅)妲�(g貌u)鐗瑰緛锛屼簩绱�(j铆)銆佷笁绱�(j铆)鍜屽洓绱�(j铆)绲�(ji茅)妲�(g貌u)姒傚康锛岀董鎸佽泲鐧借唱(zh矛)绌洪枔绲�(ji茅)妲�(g貌u)鐨勪富瑕佷綔鐢ㄥ姏銆傜啛鎮夎倢绱呰泲鐧藉拰琛€绱呰泲鐧界祼(ji茅)妲�(g貌u)鐗瑰緛浠ュ強瀹冨€戠殑姘ч＝鍜屾洸绶氬拰閻垁鍨嬬窗(x矛)鑳炶钵琛€鐥呯殑璧峰洜銆�
浜嗚В閰剁殑鍒嗛鍜屽懡鍚�锛岄叾鑸囦竴鑸偓鍖栧姂鐨勭暟鍚�锛涙帉鎻′竴浜涙蹇碉細娲诲寲鑳�銆佹椿鎬т腑蹇�銆佸弽鎳�(y墨ng)鍒濋€熷害銆佹瘮娲绘€�銆並m銆侀叾鍘�銆佸垾妲�(g貌u)閰�銆佸悓鍔熼叾銆佺(j矛ng)鐖�(zh膿ng)鎬ф姂鍒�锛岄潪绔�(j矛ng)鐖�(zh膿ng)鎬ф姂鍒�銆佹渶閬﹑H绛�锛涗簡瑙ｇ背寮忔柟绋嬪強鍏舵帹灏�(d菐o)閬庣▼锛涘奖闊块叾淇冨弽鎳�(y墨ng)鐨勫悇绋洜绱�銆備簡瑙ｅ拰鎺屾彙涓€浜涗富瑕佺殑姘存憾鎬х董鐢熺礌鐨勫悕绋�銆佺祼(ji茅)妲�(g貌u)銆佺敓鐞嗕綔鐢ㄥ拰瀹冨€戠殑杓旈叾褰㈠紡锛涗簡瑙�4绋剛婧舵€х董鐢熺礌鐨勭敓鐞嗕綔鐢ㄣ€�
浜嗚В鑴傞鐨勯鍒�銆佸姛鑳�銆佽剛鐨勫墠楂斿強琛嶇敓鐗╃殑绲�(ji茅)妲�(g貌u)鐗归粸(di菐n)锛氭帉鎻￠噸瑕佽剛鑲吀銆侀噸瑕佺７鑴傜殑绲�(ji茅)妲�(g貌u)锛涙帉鎻℃补鑴傚拰鐢樻补纾疯剛鐨勭祼(ji茅)妲�(g貌u)鑸囨€ц唱(zh矛)
鎺屾彙涓€浜涘熀鏈蹇碉細閰佃В锛岀櫦(f膩)閰�锛屽簳鐗╂按骞崇７閰稿寲锛屽反鏂痉鏁堟噳(y墨ng)锛涚啛鎮夐叺瑙ｉ€斿緫涓殑鍚勬閰朵績鍙嶆噳(y墨ng)浠ュ強鑸囩櫦(f膩)閰甸€斿緫鐨勫崁(q奴)鍒ワ紱鐔熸倝妾告閰稿惊鐠�(hu谩n)閫斿緫涓殑鍚勬閰朵績鍙嶆噳(y墨ng)锛屼互鍙婂悇姝ュ弽鎳�(y墨ng)閰剁殑浣滅敤鐗归粸(di菐n)锛涙渻(hu矛)鍒嗘瀽鍜岃▓(j矛)绠楅叺瑙ｅ拰妾告閰稿惊鐠�(hu谩n)涓敘(ch菐n)鐢熺殑鑳介噺锛屼互鍙婂簳鐗╁垎瀛愪腑妯�(bi膩o)瑷樼⒊鐨勫幓鍚戯紱浜嗚В鎴婄硸纾烽吀閫斿緫鐨勭敓鐗╁(xu茅)鎰忕京锛氭彁渚涙牳绯�-5-纾烽吀鍜孨ADPH锛涗簡瑙ｇ硸浠ｈ瑵鐨勬瑕侀€斿緫钁¤悇绯栭啗閰搁€斿緫鍙互鐢熸垚绯栭啗閰稿拰鎶楀琛€閰�锛涗簡瑙ｉ叺瑙ｅ拰绯栫暟鐢熼€斿緫宸暟
6 鐢熺墿姘у寲鑸囨哀鍖栫７閰稿寲
鐔熸倝姘у寲鑸囬倓鍘熷弽鎳�(y墨ng)鏄浣曢€氶亷闆诲瓙鍌抽仦閺堝伓鑱�(li谩n)鐨�銆傝唱(zh矛)瀛愭績搴︽搴﹀樊鏄浣曞舰鎴愮殑銆� 鎺屾彙鍖栧(xu茅)婊查€忕悊璜栫殑瑕侀粸(di菐n)锛屼互鍙婇浕瀛愬偝閬炴槸濡備綍鑸嘇DP鐨勭７閰稿寲鍋惰伅(li谩n)鐨勩€� 鐔熸倝鑳炴恫涓殑NADH杞�(zhu菐n)鎻涚偤绶氱矑楂斾腑鐨凬ADH鐨勯€斿緫銆�
7 鑴傞鐨勫垎瑙ｅ拰鍚堟垚浠ｈ瑵
閲嶉粸(di菐n)鎺屾彙鑴傝偑閰肝叉哀鍖栭亷绋�锛屽弮鑸囧弽鎳�(y墨ng)鐨勯叾銆佽紨鍩哄拰杓旈叾锛涙渻(hu矛)瑷�(j矛)绠楅＝鍜屻€佷笉椋藉拰鑴傝偑閰哥稉(j墨ng)尾姘у寲锛屾妾吀寰挵(hu谩n)鍜屾哀鍖栫７閰稿寲寰瑰簳姘у寲鐐篊O2鍜屾按鎵€鐢�(ch菐n)鐢熺殑鑳介噺锛涗簡瑙ｉ叜楂旂敓鎴愮殑閮ㄤ綅銆佺敓鎴愰亷绋嬪強鍗卞锛涗簡瑙ｈ剛鑲吀鍚堟垚鐨勯亷绋嬩互鍙婅垏鑴傝偑閰稿垎瑙ｉ亷绋嬬殑涓昏宸垾锛涗簡瑙ｇ敇娌圭７鑴備互鍙婅喗鍥洪唶鐢熺墿鍚堟垚鐨勫熀鏈€斿緫
8 铔嬬櫧璩�(zh矛)鐨勯叾淇冮檷瑙ｅ拰姘ㄥ熀閰镐唬璎�
鎺屾彙涓€浜涗富瑕佺殑姒傚康锛氳綁(zhu菐n)姘ㄤ綔鐢�锛屾哀鍖栬劔姘�锛岄偿姘ㄩ吀寰挵(hu谩n)锛岀敓閰拰鐢熺硸姘ㄥ熀閰革紝鍥烘爱浣滅敤锛涚啛鎮夐偿姘ㄩ吀寰挵(hu谩n)鐧�(f膩)鐢熺殑閮ㄤ綅锛屽惊鐠�(hu谩n)涓殑鍚勬閰朵績鍙嶆噳(y墨ng)锛屽翱绱犳爱鐨勪締婧愶紱浜嗚В姘ㄥ熀閰哥⒊楠ㄦ灦鐨勬哀鍖栭€斿緫锛岀壒鍒ユ槸鑸囦唬璎濅腑蹇冮€斿緫锛堥叺瑙ｅ拰妾告閰稿惊鐠�(hu谩n)锛夌殑闂�(gu膩n)绯伙紝浠ュ強涓€浜涙皑鍩洪吀浠ｈ瑵涓叾鐨勭己鎼嶅紩璧风殑閬哄偝?銆傛叮绉佸ぅ娼滃對鐠嬭願煎卜鎹呭對鐠嬭願煎卜閾ｅ偦骞曨姠鍏穅绋�
9 鏍搁吀鐨勯叾淇冮檷瑙ｅ拰鏍歌嫹閰镐唬璎�
鐔熸倝鍢屽懁鐠�(hu谩n)鍜屽槯鍟剁挵(hu谩n)涓婂悇鍊�(g猫)鍘熷瓙鐨勪締婧�锛涗簡瑙ｅ槍鍛ゆ牳鑻烽吀鍜屽槯鍟舵牳鑻烽吀寰為牠鍚堟垚鐨勯亷绋嬩互鍙婃渶鍒濈敘(ch菐n)鐗┿€備簩鑰呭悎鎴愰€斿緫鐨勫樊鐣�锛涗簡瑙ｆ牳鑻烽吀瑁�(b菙)鏁戝悎鎴愰€斿緫鐨勯噸瑕佹剰缇╋紱浜嗚В鏍歌嫹閰搁檷瑙ｇ殑閬庣▼鍜岀祩鐢�(ch菐n)鐗�锛屽翱閰稿爢绌嶅紩璧风殑鐤剧梾鍜屾不鐧傛柟娉�
10 鏍搁吀鐨勭敓鐗╁悎鎴�
鎺屾彙涓€浜涘熀鏈蹇碉細涓績娉曞墖锛屽崐淇濈暀寰�(f霉)鍒�锛屽墠灏�(d菐o)閺�锛屾化鍚庨張锛屽京(f霉)鍒跺弶锛屼笉閫ｇ簩(x霉)寰�(f霉)鍒�锛屽病宕庣墖娈�锛涗簡瑙ｅ咕椤濪NA鑱氬悎閰剁殑鍌寲鐗归粸(di菐n)锛孌NA寰�(f霉)鍒剁殑涓€鑸亷绋�锛屼互鍙婂師鏍哥窗(x矛)鑳炲拰鐪熸牳绱�(x矛)鑳濪NA鍚堟垚鐨勭暟鍚�锛涗簡瑙NA鎼嶅偡鍜屽咕绋慨寰�(f霉)鐨勬(j墨)鍒讹紱浜嗚ВRNA鍚堟垚娑夊強鐨勮捣濮�銆佸欢浼稿拰绲傛涓夊€�(g猫)閬庣▼锛涙帉鎻℃牳閰剁殑姒傚康
11 铔嬬櫧璩�(zh矛)鐨勭敓鐗╁悎鎴�
鎺屾彙涓€浜涘熀鏈蹇碉細瀵嗙⒓锛屽弽瀵嗙⒓锛屾皑鍩洪吀娲诲寲锛屸€滄摵鍕�(d貌ng)鈥濆(xu茅)瑾�锛涗簡瑙RNA鍒嗗瓙鍦ㄨ泲鐧借唱(zh矛)鍚堟垚涓殑浣滅敤锛涗簡瑙ｅ鑲藉悎鎴愮殑涓夊€�(g猫)閬庣▼锛屼互鍙婁竴浜涙姉鐢熺礌鍜屾瘨绱犲皪(du矛)鍚堟垚鐨勬姂鍒朵綔鐢�
12浠ｈ瑵瑾�(di脿o)绡€(ji茅)
鎺屾彙涓€浜涘熀鏈蹇碉細鍏卞児(ji脿)淇＞瑾�(di脿o)绡€(ji茅)銆侀叾鍘熸縺娲汇€佸弽楗嬫姂鍒�銆佸墠楗嬫縺娲�锛涗簡瑙ｆ搷绺卞瓙瀛�(xu茅)瑾収(n猫i)瀹�锛涘紕娓呮涓夌ó椤炲瀷鐨勬搷绺卞瓙鐨勮綁(zhu菐n)閷勮(di脿o)鎺�
涓夈€� 涓昏鍙冭€冩浉鐩�
鍩虹(ch菙)鐢熺墿鍖栧(xu茅)锛堢2鐗堬級閮椆鍏変富绶�锛岄珮绛夋暀鑲插嚭鐗堢ぞ 锛�2009骞寸2鐗堬級
鐢熺墿鍖栧(xu茅) 涓�銆佷笅鍐�(c猫)锛堢鍥涚増锛夋湵鍦ｅ簹/寰愰暦(zh菐ng)娉� 楂樼瓑鏁欒偛鍑虹増绀� 2017骞�
鍏嶈铂(z茅)鑱叉槑锛氭湰鏂囩郴杞�(zhu菐n)杓夎嚜缍�(w菐ng)绲�(lu貌)锛屽鏈変镜鐘�锛岃珛(q菒ng)鑱�(li谩n)绯绘垜鍊戠珛鍗冲埅闄�锛屽彟锛氭湰鏂囧儏浠ｈ〃浣滆€呭€�(g猫)浜鸿榛�(di菐n)锛岃垏鏈恫(w菐ng)绔欑劇闂�(gu膩n)銆傚叾鍘熷壍(chu脿ng)鎬т互鍙婃枃涓櫝杩版枃瀛楀拰鍏�(n猫i)瀹规湭缍�(j墨ng)鏈珯璀夊(sh铆)锛屽皪(du矛)鏈枃浠ュ強鍏朵腑鍏ㄩ儴鎴栬€呴儴鍒嗗収(n猫i)瀹�銆佹枃瀛楃殑鐪熷(sh铆)鎬�銆佸畬鏁存€�銆佸強鏅�(sh铆)鎬ф湰绔欎笉浣滀换浣曚繚璀夋垨鎵胯锛岃珛(q菒ng)璁€鑰呭儏浣滃弮鑰�锛屽苟璜�(q菒ng)鑷鏍稿(sh铆)鐩搁棞(gu膩n)鍏�(n猫i)瀹�銆�
鏂囩珷鎼滅储
鎮ㄧ従(xi脿n)鍦ㄧ殑浣嶇疆锛� 
