瑗垮畨鐭虫补澶у2020骞寸ⅸ澹嫑鐢熻€冭│

 锛�826锛夋湁姗熷寲瀛�   鑰冭│澶х侗

涓€銆佽€冨療鐩

瑭茶€冭│鐨勪富瑕佺洰妯欐槸鑰冨療鑰冪敓灏嶄簬鏈夋鍖栧涓殑鍩烘湰姒傚康鍜屽熀鏈悊璜�銆佷富瑕佹湁姗熷弽鎳�(y墨ng)鍙婂弽鎳�(y墨ng)姗熺悊銆佹湁姗熷悎鎴愭€濊矾銆佹湁姗熷寲鍚堢墿鐨勫垎鏋愭柟娉曠瓑鍏�(n猫i)瀹圭殑鐞嗚В鍜屾帉鎻＄▼搴︼紝瑕佹眰鑰冪敓鑳藉绯荤当(t菕ng)鍦伴亱鐢ㄦ湁姗熷寲瀛哥浉闂�(gu膩n)鐭ヨ瓨鍏�(n猫i)瀹瑰拰鏂规硶渚嗘簴纰哄垎鏋�銆佽В閲嬪拰绉戝铏曠悊宸ョ▼瀵﹂殯鍟忛銆�

浜�銆佽€冭│涓昏鍏�(n猫i)瀹�

绗竴绔�   绶�  璜�

1.1浜嗚В鏈夋鍖栧鐧�(f膩)灞曟鍙插強鏈夋鍖栧鍜屾湁姗熷寲鍚堢墿鐨勫畾缇�銆佸缈掍换鍕�(w霉)鍙婄爺绌舵柟娉�锛�

1.2 鐞嗚В鍖栧閸电悊璜栧強鍏卞児閸电殑褰㈡垚鍜屽爆鎬�锛�

1.3 鎺屾彙鍩烘湰姒傚康锛氬師瀛愯粚閬�銆佸垎瀛愮祼(ji茅)妲�(g貌u)銆佹(g貌u)閫�銆佸潎瑁�銆佺暟瑁�銆佽嚜鐢卞熀銆佷腑闁撻珨銆佽獦灏�(d菐o)鏁堟噳(y墨ng)銆佸畼鑳藉湗锛�

1.4 浜嗚В鏈夋鍖栧悎鐗╁厓绱犲垎鏋愬強绲�(ji茅)妲�(g貌u)娓畾鏂规硶銆�

绗簩绔�  鐑风兇鍜岀挵(hu谩n)鐑风兇

 2.1 鐔熺反鎺屾彙鐑风兇鐨勫悓绯诲垪銆佺暟妲�(g貌u)鍙婄兎鐑寸殑鍛藉悕锛�

 2.3 鎺屾彙鐑风兇鐨勬(g貌u)璞★細妲�(g貌u)璞＄殑瀹氱京锛屼氦鍙夊紡鑸囬噸鐤婂紡锛屾(g貌u)璞¤〃绀烘硶锛堥€忚寮忚垏Newman鎶曞奖寮忥級锛屾(g貌u)璞¤垏鑳介噺闂�(gu膩n)绯�锛�

 2.3 浜嗚В鐑风兇鐨勭墿鐞嗘€ц唱(zh矛)锛氭哺榛炪€佺啍榛�銆佹憾瑙ｅ害銆佸瘑搴﹀強璁婂寲瑕�(gu墨)寰�锛屽垎瀛愰枔鍔�锛�

2.4鎺屾彙鐑风兇鐨勫弽鎳�(y墨ng),閲嶉粸鎺屾彙鐑风兇鐨勯沟鍖栧弽鎳�(y墨ng)鍙婅嚜鐢卞熀鍙嶆噳(y墨ng)姝风▼锛�

2.5浜嗚В鐑风兇鐨勪富瑕佷締婧愬拰鐢ㄩ€�銆�

2.6 鎺屾彙鐠�(hu谩n)鐑风兇鐨勭暟妲�(g貌u)鍜屽懡鍚嶏紱

2.7浜嗚В鐠�(hu谩n)鐑风兇鐨勭墿鐞嗘€ц唱(zh矛)銆佺挵(hu谩n)鐑风兇鐨勪締婧愬拰鎳�(y墨ng)鐢�锛�

2.8 鎺屾彙鐠�(hu谩n)鐑风兇鐨勫寲瀛告€ц唱(zh矛)锛岀悊瑙ｇ挵(hu谩n)鐑风兇鐨勭祼(ji茅)妲�(g貌u)鑸囩┅(w臎n)瀹氭€х殑闂�(gu膩n)绯�锛�

2.9 鎺屾彙鐠�(hu谩n)宸辩兎鐨勬(g貌u)璞°€佺悊瑙ｅ彇浠ｇ挵(hu谩n)宸辩兎鐨勬(g貌u)璞″垎鏋�锛涗簡瑙ｅ叾瀹冨柈鐠�(hu谩n)鍙婂鐠�(hu谩n)鐠�(hu谩n)鐑风兇鐨勬(g貌u)璞�銆�

绗笁绔�  鐑兇鍜岀倲鐑�

3.1 鎺屾彙鐑兇銆佺倲鐑寸殑绲�(ji茅)妲�(g貌u)銆佺暟妲�(g貌u)鍜屽懡鍚�锛�

3.2 鐞嗚В鐑兇鐨勭浉灏嶇┅(w臎n)瀹氭€ц垏绲�(ji茅)妲�(g貌u)鐨勯棞(gu膩n)绯�锛�

3.3 鎺屾彙鐑兇銆佺倲鐑寸殑鍒舵硶锛�

   3.4浜嗚В鐑兇銆佺倲鐑寸殑鐗╃悊鎬ц唱(zh矛)锛�

3.5 閲嶉粸鎺屾彙鐑兇鐨勫弽鎳�(y墨ng)锛氬偓鍖栧姞姘�锛涜Κ闆诲姞鎴愶紙鍔犻沟绱�銆侀沟鍖栨矮銆佹按銆佹楣甸吀銆佺～閰革級锛涜嚜鐢卞熀鍔犳垚锛堥亷姘у寲鐗╂晥鎳�(y墨ng)锛�锛涚〖姘寲鍙嶆噳(y墨ng)锛涙哀鍖�锛岃嚟姘у寲锛涜仛鍚堝弽鎳�(y墨ng)锛�伪-姘殑鍙嶆噳(y墨ng)锛堥珮婧沟浠�锛屾哀鍖�锛屾皑姘у寲锛�锛涙帉鎻＄倲鐑寸殑鍙嶆噳(y墨ng)銆�

3.6 鎺屾彙瑕浕鍔犳垚鍙嶆噳(y墨ng)姗熺悊銆傜啛绶存噳(y墨ng)鐢ㄩΜ姘忚(gu墨)鍓�锛屼簡瑙ｅ崁(q奴)鍩熼伕鎿囨€у拰绔嬮珨閬告搰鎬х殑姒傚康銆傛帉鎻＄⒊姝ｉ洟瀛愮殑绌�(w臎n)瀹氭€с€佺⒊姝ｉ洟瀛愮殑閲嶆帓鍙婄儻涓欎綅閲嶆帓锛�

3.7 浜嗚В鐑兇銆佺倲鐑寸殑渚嗘簮鍜屽伐妤�(y猫)鍒舵硶銆�

绗洓绔�  浜岀儻鐑� 鍏辫粵楂旂郴

4.1 鎺屾彙浜岀儻鐑寸殑鍛藉悕锛�

4.2 鎺屾彙鍏辫粵浜岀儻鐑寸殑绲�(ji茅)妲�(g貌u)鍜屽寲瀛告€ц唱(zh矛)锛�

4.3 鐞嗚В鍙婃帉鎻￠浕瀛愰洟鍩熷強鍏辫粵鏁堟噳(y墨ng)锛�

4.4 鐞嗚В骞舵渻瀵嚭涓€鑸寲鍚堢墿鐨勫叡鎸紡锛�

4.5 浜嗚В閲嶈浜岀儻鐑寸殑宸ユキ(y猫)鍒舵硶銆�

绗簲绔�  鑺崇兇 鑺抽鎬�

5.1 鎺屾彙鑻殑绲�(ji茅)妲�(g貌u)锛涙帉鎻¤嫰鍙婅嫰琛嶇敓鐗╃殑鐣版(g貌u)銆佸垎椤炲強鍛藉悕锛�

5.2 閲嶉粸鎺屾彙鑻挵(hu谩n)涓婄殑瑕浕鍙栦唬鍙嶆噳(y墨ng)锛堥沟浠�銆佺鍖�銆佺：鍖栵紝Friedel-Crafts鍙嶆噳(y墨ng)锛夊強鍏跺弽鎳�(y墨ng)姗熺悊锛�

5.3 鐞嗚В骞舵帉鎻¤嫰鐠�(hu谩n)涓婅Κ闆诲彇浠ｅ弽鎳�(y墨ng)瀹氫綅瑕�(gu墨)寰嬶細瀹氫綅鍩虹殑鍒嗛锛屼竴鍏冨彇浠ｇ殑瀹氫綅瑕�(gu墨)寰嬪強瑙ｉ噵锛屼簩鍏冨彇浠ｈ嫰鐨勫畾浣嶈(gu墨)寰嬶紱

5.4 鎺屾彙鐑峰熀鑻殑鍏朵粬鍙嶆噳(y墨ng)锛�

5.5 浜嗚В鍠挵(hu谩n)鑺崇兇鐨勪締婧愬拰鐢ㄩ€�锛�

5.6 浜嗚В澶氱挵(hu谩n)鑺崇兇鐨勫懡鍚�銆佹€ц唱(zh矛)銆傛帉鎻¤悩鐨勬€ц唱(zh矛)鍙婂叾瀹氫綅瑕�(gu墨)鍓�锛�

5.7 浜嗚В鑺崇兇鐨勫伐妤�(y猫)渚嗘簮锛�

5.8 鐞嗚В骞舵渻鎳�(y墨ng)鐢ㄤ紤鍏嬬埦瑕�(gu墨)鍓囧垽鏂疯姵棣欐€�锛�

5.9 浜嗚В澶氬畼鑳藉湗鍖栧悎鐗╃殑鍛藉悕銆�

绗叚绔�  绔嬮珨鍖栧

6.1鎺屾彙浠ヤ笅鍩烘湰姒傚康锛氬亸鎸厜銆佹棆鍏夋€�銆佹墜鎬с€佹瘮鏃嬪厜搴�銆佸皪绋卞厓绱犮€佸皪鏄犻珨銆侀潪灏嶆槧楂�銆佸娑堟棆楂斿拰鍏�(n猫i)娑堟棆楂旂殑姒傚康锛�

6.2 鎺屾彙鍒嗗瓙鐨勫皪绋辨€у拰鎵嬫€х殑闂�(gu膩n)绯�锛�

6.3 鎺屾彙妲�(g貌u)鍨嬬殑琛ㄧず鏂规硶鍙婃墜鎬у垎瀛愮殑R/S鍛藉悕娉曪紱

6.4 浜嗚В纰崇挵(hu谩n)鍖栧悎鐗╁強涓嶅惈鎵嬫€т腑蹇冨寲鍚堢墿鐨勭珛楂旂暟妲�(g貌u)锛�

6.5 浜嗚В鎵嬫€у悎鎴愮殑姒傚康銆�

绗竷绔�  楣典唬鐑�

7.1 鎺屾彙楣典唬鐑村懡鍚嶆硶銆侀沟浠ｇ兎鐨勭祼(ji茅)妲�(g貌u)銆佸垎椤炲強鐗╃悊鎬ц唱(zh矛)锛�

7.2 鎺屾彙鑴傝偑鏃忛沟浠ｇ兇鐨勯噸瑕佸弽鎳�(y墨ng)锛氳Κ鏍稿彇浠ｅ弽鎳�(y墨ng)銆佹秷闄ゅ弽鎳�(y墨ng)銆佽垏娲绘綉閲戝爆鍙嶆噳(y墨ng)锛�

7.3 姝ｇ⒑鐞嗚В瑕牳鍙栦唬鍙嶆噳(y墨ng)鐨�SN2鍜�SN1姗熺悊鍙婃秷闄ゅ弽鎳�(y墨ng)姗熺悊锛�E1銆�E2锛�锛涙帉鎻″奖闊胯Κ鏍稿彇浠ｅ弽鎳�(y墨ng)鍙婃秷闄ゅ弽鎳�(y墨ng)鐨勫洜绱狅紱浜嗚В褰遍熆瑕牳鍙栦唬鍙嶆噳(y墨ng)鍙婃秷闄ゅ弽鎳�(y墨ng)绔剁埈鐨勬浠�銆�

7.4 鎺屾彙鍒跺倷鑴傝偑鏃忛沟浠ｇ兇鐨勬柟娉曪紱

7.5 浜嗚В楣典唬鐑风殑鐢ㄩ€�锛�

7.6 鎺屾彙鏈夋閲戝爆鍖栧悎鐗╃殑鍒跺倷鍙婄敤閫斻€�

7.7 鎺屾彙楣典唬鐑兇鍜岄沟浠ｈ姵鐑寸殑鍖栧鎬ц唱(zh矛)銆�

绗叓绔�  鏈夋鍖栧悎鐗╃殑娉㈣瓬鍒嗘瀽

8.1 鐞嗚В姘瓬鍩烘湰鍘熺悊銆傛帉鎻￠浕瀛愮殑灞忚斀鑸囧幓灞忚斀鏁堟噳(y墨ng)銆佸寲瀛镐綅绉荤殑瀹氱京銆佹湁姗熷寲鍚堢墿涓悇椤炴矮鐨勫寲瀛镐綅绉昏寖鍦�銆�n+1瑕�(gu墨)寰嬶紱鍒濇鎺屾彙NMR鍦栬瓬瑙ｆ瀽娉�锛�

8.2 鐞嗚В鍒嗗瓙绲�(ji茅)妲�(g貌u)鑸囩磪澶栧厜璀滀箣闁撶殑闂�(gu膩n)绯诲強涓昏瀹樿兘鍦樼殑鐗瑰緛鍚告敹闋荤巼锛涚悊瑙ｇ壒寰佸崁(q奴)銆佹寚绱嬪崁(q奴)銆佺磪澶栨椿鎬х瓑姒傚康锛涘垵姝ユ帉鎻′竴鑸寲鍚堢墿鐨勭磪澶栧厜璀滆В鏋愭柟娉�锛�

8.3 浜嗚В绱鍏夎瓬鐨勫師鐞嗗強涓€鑸噳(y墨ng)鐢�锛�

8.4 浜嗚В璩�(zh矛)璀滅殑涓€鑸噳(y墨ng)鐢�銆�

绗節绔�  閱囧拰閰�

 9.1 鎺屾彙閱囩殑绲�(ji茅)妲�(g貌u)銆佺暟妲�(g貌u)鍜屽懡鍚�锛�

 9.2 鎺屾彙涓€鍏冮唶鐨勫弽鎳�(y墨ng)锛屾帉鎻￠唶鐨勮Κ鏍稿彇浠�銆佹秷闄ゅ弽鎳�(y墨ng)鍙婂叾姗熺悊锛�

 9.3 鎺屾彙涓€鍏冮唶鐨勫埗娉�锛�

 9.4 浜嗚В浜屽厓閱囩殑鍛藉悕鍙婃€ц唱(zh矛)锛�

 9.5 鎺屾彙閰氱殑绲�(ji茅)妲�(g貌u)銆佺暟妲�(g貌u)鍜岀墿鐞嗘€ц唱(zh矛)锛�

 9.6 鎺屾彙涓€鍏冮厷鐨勫弽鎳�(y墨ng)銆�

绗崄绔�  閱氬拰鐠�(hu谩n)姘у寲鍚堢墿

10.1鎺屾彙閱氱殑绲�(ji茅)妲�(g貌u)銆佺暟妲�(g貌u)鍜岀墿鐞嗘€ц唱(zh矛)锛�

10.2 鎺屾彙閱氱殑鍙嶆噳(y墨ng)锛涢噸榛炴帉鎻￠啔鐨勮Κ鏍稿彇浠ｅ弽鎳�(y墨ng)鍙婃鐞�锛�

10.3 鎺屾彙閱氱殑鍒舵硶锛氶唶鑴按锛�Williamson鍚堟垚锛�

10.4 鎺屾彙鐠�(hu谩n)閱氱殑鎬ц唱(zh矛)锛涢噸榛炴帉鎻＄挵(hu谩n)姘т箼锛堜笝锛夌兎鐨勫寲瀛告€ц唱(zh矛)锛�

10.5 浜嗚В鍐犻啔鐢ㄩ€�銆�

绗崄涓€绔�  閱涖€侀叜鍜岄唽

11.1 鎺屾彙涓€鍏冮啗閰殑绲�(ji茅)妲�(g貌u)銆佺暟妲�(g貌u)鍜屽懡鍚�锛�

11.2 鎺屾彙閱涢叜鑸囨哀瑕牳瑭﹀姂銆佽垏姘Κ鏍歌│鍔�銆佽垏纰宠Κ鏍歌│鍔戠殑鍔犳垚鍙嶆噳(y墨ng)锛涙帉鎻￠啗閰殑伪-姘師瀛愮殑鍙嶆噳(y墨ng)鍜屾哀鍖栭倓鍘熷弽鎳�(y墨ng)锛�

11.3 鎺屾彙閱涢叜瑕牳鍔犳垚鍙嶆噳(y墨ng)姗熺悊鍙婄茎閱涚府鍚堝弽鎳�(y墨ng)姗熺悊锛�

11.4 鐞嗚В骞舵帉鎻￠啗鍜岄叜鐨勯叜鈥�鐑唶骞宠　鍙婃湁闂�(gu膩n)鍙嶆噳(y墨ng)锛�

11.5 鎺屾彙閱涢叜鐨勯倓鍘熷拰姘у寲鍙嶆噳(y墨ng)鍙婃噳(y墨ng)鐢紱

11.6 鎺屾彙涓€鍏冮啗閰殑鍒舵硶锛氶唶鐨勬哀鍖栧拰鑴矮锛涚倲鐑存按鍚�锛涘悓纰充簩楣典唬鐗╂按瑙�锛�Friedel-Crafts?锛涱嚞?锛涜姵鐑存哀鍖栵紱缇板熀鍚堟垚锛�

11.7 浜嗚В閱涢叜鐨勪締婧愬拰鐢ㄩ€旓紱

11.8 鎺屾彙伪,尾-涓嶉＝鍜岄啗閰殑鍛藉悕鍙婂弽鎳�(y墨ng)锛�

11.9 浜嗚В涔欑儻閰�銆佸崱璩撶殑鎬ц唱(zh矛)锛�

11.10 浜嗚В閱岀殑鍒舵硶鍙婂寲瀛告€ц唱(zh矛)銆�

绗崄浜岀珷  缇ч吀

12.1鎺屾彙涓€鍏冪晶閰哥殑绲�(ji茅)妲�(g貌u)鍙婂懡鍚�锛�

12.2鐞嗚В瑾樺皫(d菐o)鏁堟噳(y墨ng)灏嶇晶閰搁吀鎬х殑褰遍熆锛�

12.3鎺屾彙涓€鍏冪晶閰哥殑鍖栧鎬ц唱(zh矛)锛�

12.4鎺屾彙?锛涱嚞纾�?y墨ng)鐨勬鐞�锛�

12.5浜嗚В涓€鍏冪晶閰哥殑渚嗘簮鍜岀敤閫�锛�

12.6浜嗚В浜屽厓缇ч吀鎬ц唱(zh矛)锛�

12.7浜嗚В缇ュ熀閰哥殑鎬ц唱(zh矛)銆�

绗崄涓夌珷  缇ч吀琛嶇敓鐗�

13.1鎺屾彙缇ч吀琛嶇敓鐗╃殑绲�(ji茅)妲�(g貌u)鍜屽懡鍚�锛涖€€

13.2浜嗚В缇ч吀琛嶇敓鐗╃殑鐗╃悊鎬ц唱(zh矛)锛�

13.3鎺屾彙缇ч吀琛嶇敓鐗╃殑姘磋В鍙嶆噳(y墨ng)鍙婂叾姗熺悊锛涢噸榛炴帉鎻￠叝鐨勬按瑙ｅ弽鎳�(y墨ng)鍙婂叾姗熺悊锛�

13.4鎺屾彙缇ч吀琛嶇敓鐗╃殑鍏跺畠鍙嶆噳(y墨ng)锛氶唶瑙�銆佹皑瑙�銆侀倓鍘熷拰鑸�Grignard瑭﹀姂鐨勫弽鎳�(y墨ng)锛涙帉鎻�?锛涱媱H鏍稿彇浠ｅ弽鎳�(y墨ng)姗熺悊锛�

13.5浜嗚В缇ч吀琛嶇敓鐗╃殑鐢ㄩ€�锛�

13.6浜嗚В纰抽吀琛嶇敓鐗╃殑鎬ц唱(zh矛)鍙婄敤閫�銆�

绗崄鍥涚珷  尾鈥�浜岀景鍩哄寲鍚堢墿

14.1 鎺屾彙閰�-鐑唶浜掕畩鐣版(g貌u)锛�

14.2 鎺屾彙涔欓叞涔欓吀涔欓叝鐨勫熀鏈€ц唱(zh矛)鍜屽湪鏈夋鍚堟垚涓殑鎳�(y墨ng)鐢�锛�

14.3 鎺屾彙涓欎簩閰镐簩涔欓叝鐨勫熀鏈€ц唱(zh矛)鍜屽湪鏈夋鍚堟垚涓殑鎳�(y墨ng)鐢�锛�

14.4 鎺屾彙閭佸厠鐖惧弽鎳�(y墨ng)鍙婂湪鏈夋鍚堟垚涓殑鎳�(y墨ng)鐢紱

14.5 浜嗚В鍚椿娼戜簽鐢插熀鍖栧悎鐗╃殑鎬ц唱(zh矛)銆�

绗崄浜旂珷  鑳�

15.1浜嗚В纭濆熀鍖栧悎鐗╁懡鍚嶃€佸埗娉�銆佹€ц唱(zh矛)锛涙帉鎻¤姵棣欐棌纭濆熀鍖栧悎鐗╃殑鍒舵硶銆佸強鍖栧鎬ц唱(zh矛)锛堥倓鍘�銆佽姵鐠�(hu谩n)涓婄殑鍙栦唬绛夛級锛�

15.2鎺屾彙鑳虹殑鍒嗛銆佺祼(ji茅)妲�(g貌u)鍜屽懡鍚�锛�

15.3浜嗚В涓€鍏冭兒鐨勭墿鐞嗘€ц唱(zh矛)锛涚悊瑙ｅ苟鏈冨垽鏂疯兒鐨勫牽鎬�锛�

15.4鎺屾彙鑳虹殑鍙嶆噳(y墨ng): 鑳虹兇鍩哄寲锛�?锛涱姮?锛涚：?锛涱嚇?/SPAN>Hinsberg鍙嶆噳(y墨ng)锛�锛涜垏浜炵閰哥殑鍙嶆噳(y墨ng)锛涙哀鍖栵紱鑺崇挵(hu谩n)涓婂彇浠�锛涚暟鑵堝寲鍙嶆噳(y墨ng)锛�

15.5鎺屾彙鑳虹殑鍒舵硶锛�

15.6 浜嗚В浜岃兒銆佷笉椋藉拰鑳哄拰鍙栦唬鑳虹殑鎬ц唱(zh矛)锛�

15.7 鎺屾彙瀛ｉ姩楣藉拰姘哀鍖栧洓鐑村熀閵ㄧ殑鍛藉悕銆佸埗鍌欒垏鍙嶆噳(y墨ng)锛�

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