2020骞存柊閯�(xi膩ng)閱�(y墨)瀛�(xu茅)闄�鑰冪爺澶х侗

銆婅棩瀛�(xu茅)缍滃悎(浜�)銆嬶紙浠ｇ⒓锛�704锛夎€冭│澶х侗
鈪� 鑰冭│鎬ц唱(zh矛)
钘ュ(xu茅)缍滃悎鑳藉姏鏄偤楂樼瓑闄㈡牎鎷涙敹钘ュ(xu茅)椤炵ⅸ澹爺绌剁敓鑰岃ō(sh猫)缃殑锛� 鏄叿鏈夐伕鎷旀€ц唱(zh矛)鐨勫叆瀛�(xu茅)
鑰冭│绉戠洰锛屼綔鐐哄(xu茅)鏍″懡椤屽懢鑰冪敓寰�(f霉)缈�(x铆)鐨勪緷鎿�(j霉), 娉ㄩ噸娓�(c猫)瑭�(p铆ng)鑰冪敓鐨勭稖鍚堣兘鍔涘懢鍩烘湰绱犺唱(zh矛)锛� 瑕佹眰
鑰冪敓鍏锋湁鍫�(ji膩n)瀵�(sh铆)銆佺郴绲�(t菕ng)鍛惧寤ｇ殑鑸囨キ(y猫)鍩虹(ch菙)鐭ヨ瓨(sh铆)鍛剧悊璜栦互閬�(d谩)鍒伴噸榛�(di菐n)闄㈡牎钘ュ(xu茅)鍛剧浉鍏茶垏妤�(y猫)鏈鐢熸噳(y墨ng)
鍏锋湁鐨勫(xu茅)璀�(sh铆)鍛炬按骞�銆�
鈪� 鑰冩煡鐩(bi膩o)
钘ュ(xu茅)缍滃悎鑳藉姏鑰冭│鍖呮嫭钘ョ悊瀛�(xu茅)鍛剧敓鐗╁寲瀛�(xu茅)鍏╅杸瑾茬▼锛� 瑕佹眰鑰冪敓绯荤当(t菕ng)鎺屾彙钘ョ悊瀛�(xu茅)鍛剧敓鐗�
鍖栧(xu茅)鐨勫熀绀�(ch菙)鐞嗚珫銆佸熀鏈煡璀�(sh铆)鍛惧熀鏈妧鑳斤紝骞朵笍鑳藉閬�(y霉n)鐢ㄩ€欎簺鐭ヨ瓨(sh铆)鍒嗘瀽瑙ｆ焙瀵�(sh铆)闅涘晱椤�銆�
钘ョ悊瀛�(xu茅)鏄熀绀�(ch菙)閱�(y墨)瀛�(xu茅)鍛捐嚚搴婅棩瀛�(xu茅)鐨勪富骞插(xu茅)绉�锛屼篃鏄啱(y墨)瀛�(xu茅)鍛捐棩瀛�(xu茅)銆佸熀绀�(ch菙)鍛捐嚚搴婄殑姗嬫瀛�(xu茅)绉�锛�
鍦ㄦ柊钘ョ爺绌堕亷绋嬩腑锛岃棩鐞嗗(xu茅)鍦ㄦ柊钘ラ澏榛�(di菐n)鐨勭爺绌�锛屾柊钘ョ殑鎴愯棩鎬ц⿻(p铆ng)鍍�(ji脿)锛岃嚚搴婂墠钘ユ晥瀛�(xu茅)銆佽棩浠ｅ(xu茅)
鐨勭爺绌朵腑鑷冲叢閲嶈锛屽洜姝�锛岃姹傝€冪敓鍊�?c猫)瓒疻(xu茅)缈�(x铆)闋�(l菒ng)鏈�(hu矛)钘ョ悊瀛�(xu茅)鍩虹(ch菙)鐭ヨ瓨(sh铆)鐨勫熀绀�(ch菙)涓�锛屾帉鎻¤棩鐞嗗(xu茅)鐨�
鍩烘湰姒傚康鍛捐棩鐞嗗(xu茅)姣忕珷绡€(ji茅)鐨勭稉(j墨ng)鍏歌棩鐗�锛屽寘鎷瘡绔犵瘈(ji茅)浠ｈ〃钘ョ墿鐨勮棩鐞嗕綔鐢�銆佷綔鐢ㄦ(j墨)鍒�銆佽棩浠ｅ嫊(d貌ng)
鍔涘(xu茅)鍙婁笇鑹弽鎳�(y墨ng)锛涚啛鎮夎棩鐞嗗(xu茅)涓唬琛ㄨ棩鐗╀互澶栫殑姣忓€�(g猫)钘ョ墿锛岀啛鎮夎棩鐞嗗(xu茅)鐮旂┒鐨勬渶鏂伴€�(j矛n)灞�銆傛湰
鑰冭│澶х侗锛屽苟涓屽眬闄愪簫鏇告湰鐭ヨ瓨(sh铆)锛屽叾涓� 20%鐨勫収(n猫i)瀹圭偤鏂拌棩鐨勬渶鏂扮爺绌堕€�(j矛n)灞曪紝甯屾湜澶у鍏叉敞
钘ョ悊瀛�(xu茅)鐨勯€�(j矛n)灞�銆�
鐢熺墿鍖栧(xu茅)鏄敓鍛界瀛�(xu茅)鐨勯噸瑕佸熀绀�(ch菙)瀛�(xu茅)绉戝懢鍓嶆部瀛�(xu茅)绉�锛屾槸鑷ㄥ簥閱�(y墨)瀛�(xu茅)銆佸熀绀�(ch菙)閱�(y墨)瀛�(xu茅)銆佽棩瀛�(xu茅)绛夊(xu茅)绉�
鐨勯噸瑕佺悊璜栬绋�?锛佹浮顚濋敇鐦淲(xu茅)銆嬮噸榛�(di菐n)鑰冩煡鐢熺墿鍖栧(xu茅)鐨勫熀绀�(ch菙)鐭ヨ瓨(sh铆)銆佸熀鏈悊璜�锛屾敞閲嶈€冩煡鐞嗚珫鑱�(li谩n)
绯诲(sh铆)闅涘懢缍滃悎鍒嗘瀽鑳藉姏銆傛纰哄湴鐞嗚В鍛炬帉鎻＄敓鐗╁寲瀛�(xu茅)鏈夊叢鐨勫熀鏈蹇�銆佺悊璜�銆佽(gu墨)寰嬪懢璜栨柗锛�
閬�(y霉n)鐢ㄦ帉鎻＄殑鍩虹(ch菙)鐞嗚珫鐭ヨ瓨(sh铆)鍛惧師鐞嗗垎鏋愬懢瑙ｆ焙鍟忛銆傝姹傝€冪敓绯荤当(t菕ng)婧�(zh菙n)纰哄湴鎺屾彙鐢熺墿鍖栧(xu茅)鐨勫熀鏈�
姒傚康銆佸熀绀�(ch菙)鐭ヨ瓨(sh铆)鍛惧熀鏈悊璜栵紱鎺屾彙鍚勯鐢熷寲鐗╄唱(zh矛)鐨勭祼(ji茅)妲�(g貌u)銆佹€ц唱(zh矛)鍛惧姛鑳藉強鍏跺悎鎴愪唬璎濆懢鍒嗚В浠�
璎濈殑鍩烘湰閫斿緫鍙婅(di脿o)鎺э紝鐞嗚В鍩哄洜琛ㄩ仈(d谩)鍙婅(di脿o)鎺у懢鍩哄洜宸ョ▼鐨勫熀鏈悊璜�锛屼簡瑙ｇ敓鐗╁寲瀛�(xu茅)鐨勬渶鏂伴€�(j矛n)

灞�銆�
鈪�.鑰冭│褰㈠紡瑭﹀嵎绲�(ji茅)妲�(g貌u)鍜屽収(n猫i)瀹�
涓€銆佽│鍗锋豢鍒嗗強鑰冭│鏅�(sh铆)闁�
鏈│鍗锋豢鍒嗙偤 300 鍒�锛岃€冭│鏅�(sh铆)闁撶偤 180 鍒嗛悩銆�
浜�銆佺瓟椤屾柟寮�
绛旈鏂卞紡鐐洪枆鍗�銆佺瓎瑭︺€�
涓�銆佽│鍗峰収(n猫i)瀹圭祼(ji茅)妲�(g貌u)
钘ョ悊瀛�(xu茅)鍗� 50%锛岀敓鐗╁寲瀛�(xu茅)鍗� 50%銆�
鍥�銆佽│鍗烽鍨嬬祼(ji茅)妲�(g貌u)
鍠爡(xi脿ng)閬告搰椤� 锛�50%锛�锛屽悕瑭炶В閲嬶紙20%锛夛紝绨＄瓟椤岋紙10%锛� 锛岃珫杩伴锛�20%锛�
鈪ｈ€冩煡鍏�(n猫i)瀹�
涓€銆佽棩鐞嗗(xu茅)
锛堜竴锛夎棩鐞嗗(xu茅)绺借珫
钘ョ悊瀛�(xu茅)绺借珫鍖呮嫭绺借珫銆佽棩鏁堝(xu茅)銆佽棩鍕�(d貌ng)瀛�(xu茅)鍛惧奖闊胯棩鐗╀綔鐢ㄧ殑鍥犵礌鍙婂悎鐞嗙敤钘�銆傝姹傝€冪敓鎺�
鎻¤棩鐞嗗(xu茅)鐨勫熀鏈蹇�锛涚啛鎮夎棩鐞嗗(xu茅)鐧�(f膩)灞曠啊鍙�,钘ョ悊瀛�(xu茅)鐮旂┒鐨勭洰鐨�,钘ョ悊瀛�(xu茅)鐮旂┒鐨勬柋娉�銆�
1. 鎺屾彙钘ョ悊瀛�(xu茅)鐨勫熀鏈蹇点€�
2. 鐔熸倝钘ョ悊瀛�(xu茅)鐨勭爺绌跺収(n猫i)瀹�銆�
3. 钘ョ墿浣滅敤鐨勯伕鎿囨€�銆�
4. 钘ョ墿涓岃壇鍙嶆噳(y墨ng)锛堝寘鎷壇浣滅敤銆佹瘨鎬у弽鎳�(y墨ng)銆侀亷鏁忓弽鎳�(y墨ng)銆佸悗閬烘晥鎳�(y墨ng)銆佺壒鐣拌唱(zh矛)鍙嶆噳(y墨ng)銆佺壒娈婃瘨鎬э級銆�
5. 钘ョ墿浣滅敤鐨勯噺鏁堝叢绯诲懢閲忔晥鏇茬窔銆丒D50銆丩D50銆佸畨鍏ㄦ寚鏁�(sh霉)銆�
6. 鍙楅珨鍙婂叾绲�(ji茅)鍚堢壒鎬�銆�
7. 鍙楅珨婵€鍕�(d貌ng)鍔�銆佸弽鍚戞縺鍕�(d貌ng)鍔戙€佸彈楂旀嫯鎶楀姂銆佽畩妲�(g貌u)瑾�(di脿o)绡€(ji茅)鍔�銆�

8. 鎺屾彙钘ョ墿鍦ㄩ珨鍏�(n猫i)鐨勫熀鏈亷绋嬨€�
9. 鎺屾彙琚嫊(d貌ng)杞�(zhu菐n)閬�(y霉n)鍙婄啊鍠摯(ku貌)鏁ｇ殑鐗归粸(di菐n)銆�
10锛� 鎺屾彙钘ュ嫊(d貌ng)瀛�(xu茅)鐨勫父鐢ㄥ熀鏈蹇碉紙棣栧叢鏁堟噳(y墨ng)銆佽倽鑵稿惊鐠�(hu谩n)銆丗銆乂d銆乼1/2銆乲銆� CL銆丄UC銆�
Css 绛夛級銆�
11锛� 钘ョ墿鐩镐簰浣滅敤鐨勫垎椤炲強鍏跺収(n猫i)瀹广€�
锛堜簩锛夊偝鍑虹缍�(j墨ng)绯荤当(t菕ng)钘ョ悊
鍌冲嚭绁炵稉(j墨ng)绯荤当(t菕ng)钘ョ悊鍒嗗垾鐐哄偝鍑虹缍�(j墨ng)绯荤当(t菕ng)钘ョ悊姒傝堪銆佽喗鍫垮彈楂旀縺鍕�(d貌ng)钘ャ€佹姉鑶藉牽閰叾钘ュ懢鑶�
鍫块叝閰跺京(f霉)娲昏棩銆佽喗鍫垮彈楂旈樆鏂疯棩鈥曗€昅 鑶藉牽鍙楅珨闃绘柗钘�銆侊籍鑶藉牽鍙楅珨闃绘柗钘�锛岃厧涓婅吅绱犲彈楂�
婵€鍕�(d貌ng)钘ャ€佽厧涓婅吅绱犲彈楂旈樆鏂疯棩銆侻銆丯銆佄�銆佄� 鍙楅珨鐨勬帉鎻￠潪甯搁噸瑕�锛屽叾婵€鍕�(d貌ng)鍔戝懢鎷姉鍔戠殑
浣滅敤鐗归粸(di菐n)鎺屾彙鏈夊姪浜嶈€冪敓缍滃悎浜嗚В鏈珷绡€(ji茅)鐨勭煡璀�(sh铆)榛�(di菐n)銆�
1锛� 鎺屾彙鑵庝笂鑵虹礌鍙楅珨銆佽喗鍫胯兘鍙楅珨鍙� DA 鍙楅珨鐨勪富瑕佸垎甯�銆佺敓鐞嗘晥鎳�(y墨ng)锛屾帉鎻″偝鍑虹缍�(j墨ng)绯荤当(t菕ng)
钘ョ墿鐨勫垎椤�銆�
2锛� 鎺屾彙姣涙灉钑撻鍫�銆佹柊鏂殑鏄�銆佹瘨鎵佽眴鍫跨殑浣滅敤銆佹噳(y墨ng)鐢ㄥ強涓昏涓岃壇鍙嶆噳(y墨ng)锛涙湁姗�(j墨)纾烽吀閰殑
涓瘨姗�(j墨)鍒讹紝闃挎墭鍝佸懢纰樿В纾峰畾锛堟隘瑙ｇ７瀹氾級鐨勮В姣掓(j墨)鍒�锛涙帉鎻￠樋鎵樺搧鐨勪綔鐢�銆佹噳(y墨ng)鐢ㄥ強涓岃壇鍙�
鎳�(y墨ng)锛涘北鑾ㄨ彧鍫裤€佹澅鑾ㄨ彧鍫�銆佸梾涓欒兒澶灄鐨勪綔鐢ㄧ壒榛�(di菐n)鍙婃噳(y墨ng)鐢�锛涚惀鐝€鑶藉牽銆佺瓛绠瘨鍫跨殑钘ョ悊浣滅敤
鍙婁綔鐢ㄦ(j墨)鍒�銆侀珨鍏�(n猫i)閬庣▼鍙婅嚚搴婄敤閫�锛屼笇鑹弽鎳�(y墨ng)鍛炬噳(y墨ng)鐢ㄦ檪(sh铆)鐨勬敞鎰忎簨闋�(xi脿ng)銆�
3锛庤厧涓婅吅绱�銆佸幓鐢茶厧涓婅吅绱�銆佺暟涓欒厧涓婅吅绱犲皪(du矛)鍙楅珨鐨勯伕鎿囨€�銆侀珨鍏�(n猫i)閬庣▼銆佽嚚搴婃噳(y墨ng)鐢�銆佷笇鑹�
鍙嶆噳(y墨ng)鍙婄蹇岀櫏锛涘崁(q奴)鍒ヤ笂杩颁笁鍊�(g猫)鍙楅珨婵€鍕�(d貌ng)鍔戝皪(du矛)蹇冪巼銆佹敹绺銆佽垝寮靛鐨勫奖闊垮強鍏跺湪浼戝厠娌荤檪涓�
鐨勬噳(y墨ng)鐢�锛浳� 鍙楅珨闃绘柗钘ュ懢 尾 鍙楅珨闃绘柗钘ュ皪(du矛)琛€娴佸嫊(d貌ng)鍔涘(xu茅)鐨勫奖闊夸互鍙婁綔鐢�銆佷綔鐢ㄦ(j墨)鍒躲€佽嚚搴婃噳(y墨ng)鐢�
鍛句笇鑹弽鎳�(y墨ng)銆�
锛堜笁锛変腑妯炵缍�(j墨ng)绯荤当(t菕ng)钘ョ悊瀛�(xu茅)
涓绁炵稉(j墨ng)绯荤当(t菕ng)钘ョ悊瀛�(xu茅)涓昏璎涜堪楹婚唹钘�銆侀幃(zh猫n)闈滃偓鐪犺棩銆佹姉鐧茬檱钘ュ懢鎶楅鍘ヨ棩銆佹不鐧備腑妯為€€

琛屾€х梾璁婄殑钘ョ墿銆佹姉绮剧澶卞父钘ャ€侀幃(zh猫n)鐥涜棩锛堟垚鐧€ч幃(zh猫n)鐥涜棩锛�銆佽В鐔遍幃(zh猫n)鐥涙姉鐐庤棩锛堥潪鐢鹃珨鎶楃値
钘ワ級绛夊収(n猫i)瀹�銆�
1锛庣啛鎮夊叏韬夯閱夎棩鍛惧眬閮ㄩ夯閱夎棩鐨勫垎椤�銆佹噳(y墨ng)鐢ㄣ€佸惛鏀舵瘨鎬�銆�
2. 鎺屾彙鍦拌タ娉�銆佷竵铻虹挵(hu谩n)閰懢鍞戝悺鍧︾殑鍒嗛銆佽棩鐞嗕綔鐢ㄥ強浣滅敤姗�(j墨)鍒跺強閲忔晥瑕�(gu墨)寰�銆佽棩鍕�(d貌ng)瀛�(xu茅)鐗归粸(di菐n)銆�
鑷ㄥ簥鎳�(y墨ng)鐢ㄥ懢涓昏涓岃壇鍙嶆噳(y墨ng)銆�
3锛庤嫰濡ヨ嫳閳�銆佸崱棣タ骞�銆佽嫰宸存瘮濡�銆佷箼鐞ヨ兒銆佷笝鎴婇吀閳�銆佹墭鍚￠叝鍙婂姞宸村櫞姹€鐨勮棩鐞嗕綔鐢�銆�
浣滅敤姗�(j墨)鍒朵笉鑷ㄥ簥鎳�(y墨ng)鐢�
4锛庢帉鎻″笗閲戞．鐥呯殑鐧�(f膩)鐥呮(j墨)鍒跺強鎶楀笗閲戞．鐥呰棩鐗╃殑浣滅敤鏂卞紡锛屾帉鎻″乏鏃嬪宸村懢鑻捣绱㈡不鐧傚笗
閲戞．鐥呬綔鐢ㄦ(j墨)鍒�銆佺壒榛�(di菐n)鍙婁富瑕佷笇鑹弽鎳�(y墨ng)锛岀啛鎮夊崱姣斿宸�銆侀噾鍓涚兎鑳�銆佹捍闅变涵銆佽憠渚嗗悏铇瓑鐨�
浣滅敤鐗归粸(di菐n)銆�
5锛庢帉鎻℃隘涓欏棯銆佹隘姘钩銆佺⒊閰搁嫲銆佷笁鐠�(hu谩n)椤�銆丯A銆�5-HT 鍐嶆敐鍙栨姂鍒惰棩鍛� MAO 鎶戝埗钘ョ殑钘�
鐞嗕綔鐢ㄥ強姗�(j墨)鍒�, 钘ョ墿鐩镐簰浣滅敤銆佽嚚搴婃噳(y墨ng)鐢�銆佸父瑕嬩笇鑹弽鎳�(y墨ng)鍙婃噳(y墨ng)鐢ㄦ敞鎰忎簨闋�(xi脿ng)銆�
6锛庢帉鎻″棊鍟°€佸搶鏇垮畾鐨勮棩鐞嗕綔鐢�锛岀敤閫斿強涓岃壇鍙嶆噳(y墨ng)锛屽櫞浠栦綈杈涚殑浣滅敤鐗归粸(di菐n)鍙婅嚚搴婄敤閫�銆傜啛
鎮夊叾浠栭幃(zh猫n)鐥涜棩鐨勬噳(y墨ng)鐢紝鐞嗚В闃跨墖鍙楅珨鎷姉钘ョ殑鑷ㄥ簥鎰忕京銆�
7锛庢帉鎻¤В鐔遍幃(zh猫n)鐥涙姉鐐庤棩鐨勫叡鍚屼綔鐢ㄥ強鍏舵(j墨)鍒讹紝鎺屾彙闃胯憠鍖规灄鐨勪綔鐢ㄧ壒榛�(di菐n)銆佺敤閫斿強甯歌涓岃壇
鍙嶆噳(y墨ng)锛屼簡瑙ｅ叾浠栭鍒ョ殑瑙ｇ啽閹�(zh猫n)鐥涙姉鐐庤棩鐨勪綔鐢ㄧ壒榛�(di菐n)銆佺敤閫斿強涓岃壇鍙嶆噳(y墨ng)銆�
锛堝洓锛夊績琛€绠＄郴绲�(t菕ng)钘ョ悊瀛�(xu茅)
蹇冭绠＄郴绲�(t菕ng)钘ョ悊瀛�(xu茅)鍖呮嫭闆㈠瓙閫氶亾鍙婇垼閫氶亾闃绘化钘�銆佹姉蹇冨緥澶卞父钘ャ€佽厧绱犺绠＄穵寮电礌绯荤当(t菕ng)
钘ョ墿銆佸埄灏胯棩鍙婅劔姘磋棩銆佹姉楂樿澹撹棩銆佹不鐧傚厖琛€鎬у績鍔涜“绔棩銆佹姉蹇冪禐鐥涜棩銆佹姉鍕�(d貌ng)鑴堢播妯ｇ‖
鍖栬棩鍛鹃檷琛€鑴傝棩銆傚績琛€绠＄郴绲�(t菕ng)钘ョ悊瀛�(xu茅)涓墍浠嬬垂鐨勮棩鐗╀笇鑳藉壊瑁傚皪(du矛)寰�锛岄渶瑕佸湪鍏呭垎鐞嗚В蹇冭绠�
鐢熺悊瀛�(xu茅)鐨勫熀绀�(ch菙)涓�锛屾帉鎻¤棩鐗╃殑钘ョ悊浣滅敤鍙婁綔鐢ㄦ(j墨)鍒躲€佽嚚搴婃噳(y墨ng)鐢�銆佽棩浠ｇ壒鎬у強涓岃壇鍙嶆噳(y墨ng)銆�
1锛庣啛鎮夐垼閫氶亾鐨勯鍨嬩笉閳ｉ€氶亾闃绘化钘ョ殑鍒嗛锛屾帉鎻￠垼閫氶亾闃绘化钘ョ殑钘ョ悊浣滅敤涓嶈嚚搴婃噳(y墨ng)鐢�锛�

鎺屾彙甯哥敤閳ｉ€氶亾闃绘化钘ョ殑浣滅敤鍙婄敤閫旂壒榛�(di菐n)銆�
2锛庣啛鎮夊績寰嬪け甯哥殑闆荤敓鐞嗘(j墨)鍒跺強鎶楀績寰嬪け甯歌棩鐨勫熀鏈浕鐢熺悊浣滅敤锛屾帉鎻℃姉蹇冨緥澶卞父钘ョ殑钘�
鐞嗕綔鐢�锛岃嚚搴婃噳(y墨ng)鐢ㄥ懢涓岃壇鍙嶆噳(y墨ng)銆�
3锛庣啛鎮夎厧绱犺绠＄穵寮电礌绯荤当(t菕ng)鐨勭敓鐞嗗姛鑳�锛涙帉鎻¤绠＄穵寮电礌 I 杞�(zhu菐n)鍖栭叾鎶戝埗钘ュ強琛€绠＄穵寮电礌 II
鍙楅珨鎷姉钘ョ殑钘ョ悊浣滅敤鍛句綔鐢ㄦ(j墨)鍒�锛涙帉鎻¤绠＄穵寮电礌 I 杞�(zhu菐n)鍖栭叾鎶戝埗钘ュ強琛€绠＄穵寮电礌 II 鍙楅珨鎷�
鎶楄棩鐨勪唬琛ㄨ棩鐨勮嚚搴婃噳(y墨ng)鐢ㄥ懢涓岃壇鍙嶆噳(y墨ng)銆�
4锛庣啛鎮夊埄灏胯棩浣滅敤鐨勭敓鐞嗗熀绀�(ch菙)鍙婂悇椤炲埄灏胯棩鐨勮棩鐞嗕綔鐢ㄥ強浣滅敤姗�(j墨)鍒�锛涙帉鎻″埄灏胯棩鑷ㄥ簥鎳�(y墨ng)鐢�
鍙婃噳(y墨ng)鐢ㄥ師鍓囥€佷富瑕佷笇鑹弽鎳�(y墨ng)鍙婄敤钘ユ敞鎰忎簨闋�(xi脿ng)锛屼簡瑙ｈ劔姘磋棩鐨勪綔鐢ㄦ(j墨)鍒�锛岀啛鎮夊叾鑷ㄥ簥鐢ㄩ€斻€�
5锛庢帉鎻℃姉楂樿澹撹棩鐗╁垎椤炲強浠ｈ〃鎬ц棩鐗�锛岀敳鍩哄宸淬€佸埄鑸嶅钩銆佹櫘钀樻礇鐖�銆佸搶鍞戝棯銆佺鑻湴
骞�銆佽偧灞堝棯銆佺鏅垑銆佹矮姘櫥鍡�銆佸崱鎵樻櫘鍒╅檷澹撲綔鐢ㄧ壒榛�(di菐n)銆佹噳(y墨ng)鐢ㄥ強涓岃壇鍙嶆噳(y墨ng)锛�
6锛庝簡瑙ｆ參鎬у績鍔熻兘涓屽叏鏅�(sh铆)蹇冭嚐鐨勭梾鐞嗙敓鐞嗘敼璁婂強娌荤檪钘ョ墿鍒嗛锛屾帉鎻″挤(qi谩ng)蹇冭嫹鐨勮棩鐞嗕綔鐢�銆�
鑷ㄥ簥鎳�(y墨ng)鐢ㄣ€佽棩浠ｅ嫊(d貌ng)鍔涘(xu茅)鐗归粸(di菐n)鍙婁笇鑹弽鎳�(y墨ng)涓嶉槻娌�锛屾帉鎻¤绠＄穵寮电礌鈪犺綁(zhu菐n)鍖栭叾鎶戝埗钘ュ懢琛€绠＄穵寮�
绱犫叀鍙楅珨鎷姉钘ユ姉鎱㈡€у績鍔熻兘涓屽叏鐨勪綔鐢ㄥ強鍏舵(j墨)鍒讹紝鐔熸倝琛€绠℃摯(ku貌)寮佃棩銆佄� 鍙楅珨闃绘柗钘ュ強闈炶嫹
椤炴鎬ц倢鍔涘挤(qi谩ng)蹇冭棩鐨勬姉鎱㈡€у績鍔熻兘涓屽叏浣滅敤銆�
7锛庢帉鎻＄閰搁叝椤�銆佄�-鍙楅珨闃绘柗钘�銆侀垼鎷姉鐨勬姉蹇冪禐鐥涙(j墨)鍒�锛屾帉鎻″悇椤炴姉蹇冭倢缂鸿钘ョ殑鍒嗛
鍛捐嚚搴婄敤閫�銆�
锛堜簲锛夎娑茬郴绲�(t菕ng)钘ョ墿
琛€娑茬郴绲�(t菕ng)钘ョ墿涓昏鍖呮嫭锛氳倽绱�銆侀惖鍔�銆佸彺閰稿強缍敓绱狅饥12銆佽彲娉曟灄銆侀張婵€閰�銆佺董鐢熺礌
锛�銆佸彸鏃嬬硸閰愮瓑钘ョ墿銆傛帉鎻¤倽绱�銆侀惖鍔�銆佸彺閰稿強缍敓绱狅饥12銆佽彲娉曟灄銆侀張婵€閰躲€佺董鐢熺礌锛�銆�
鍙虫棆绯栭厫鐨勪綔鐢ㄥ強鎳�(y墨ng)鐢ㄣ€�
锛堝叚锛夎嚜楂旀椿鎬х墿璩�(zh矛)鍜岀祫鑳哄強绲勮兒鍙楅珨闃绘柗钘�
鑷珨娲绘€х墿璩�(zh矛)鍛剧祫鑳哄強绲勮兒鍙楅珨闃绘柗钘ヤ富瑕佽瑳瑙ｏ細绲勮兒 H1銆丠2銆丠3 鍙楅珨闂�(gu膩n)濂敘(ch菐n)鐢熺殑鏁�

鎳�(y墨ng)鍙婂叾闃绘柗钘ョ殑浣滅敤锛涚祫鑳� H1 鍙楅珨婵€鍕�(d貌ng)钘ュ懢 H1銆丠2 鍙楅珨闃绘柗钘ョ殑鑷ㄥ簥鎳�(y墨ng)鐢ㄥ強涓昏涓岃壇鍙�
鎳�(y墨ng)銆備簡瑙ｇ祫鑳� H1銆丠2銆丠3 鍙楅珨闂�(gu膩n)濂敘(ch菐n)鐢熺殑鏁堟噳(y墨ng)鍙婂叾闃绘柗钘ョ殑浣滅敤锛屾帉鎻＄祫鑳� H1 鍙楅珨婵€鍕�(d貌ng)
钘ュ懢 H1銆丠2 鍙楅珨闃绘柗钘ョ殑鑷ㄥ簥鎳�(y墨ng)鐢ㄥ強涓昏涓岃壇鍙嶆噳(y墨ng)銆�
锛堜竷锛変綔鐢ㄤ簬鍛煎惛绯荤当(t菕ng)鐨勮棩鐗�
1. 鐔熸倝閹�(zh猫n)鍜宠棩銆佺鐥拌棩鐨勮嚚搴婄敤閫�銆�
2锛庢帉鎻″悇椤炲钩鍠樿棩鐨勪綔鐢ㄦ(j墨)鍒讹紝骞冲枠钘ヨ尪鍫块銆佽厧涓婅吅绱犲彈楂旀縺鍕�(d貌ng)钘�銆佽厧涓婅吅鐨唱(zh矛)婵€绱犻
鍛捐偉澶х窗(x矛)鑳炶啘绌�(w臎n)瀹氳棩鐨勮嚚搴婃噳(y墨ng)鐢ㄥ強鍏朵笇鑹弽鎳�(y墨ng)銆�
锛堝叓锛変綔鐢ㄤ簬娑堝寲绯荤当(t菕ng)钘ョ墿
浣滅敤浜嶆秷鍖栫郴绲�(t菕ng)钘ョ墿涓昏鍖呮嫭锛氱€夎棩涓嶆鐎夎棩銆佸姪娑堝寲钘�銆佹姉娑堝寲鎬ф桨鐦嶈棩銆備簡瑙ｇ€夎棩
涓嶆鐎夎棩銆佸姪娑堝寲钘�锛屾帉鎻℃姉娑堝寲鎬ф桨鐦嶈棩鐨勫垎椤炲強鎳�(y墨ng)鐢ㄣ€�
锛堜節锛夊収(n猫i)鍒嗘硨绯荤当(t菕ng)钘ョ悊瀛�(xu茅)
鍏�(n猫i)鍒嗘硨绯荤当(t菕ng)钘ョ悊瀛�(xu茅)鍖呮嫭鑵庝笂鑵虹毊璩�(zh矛)婵€绱犻钘ョ墿銆佺敳鐙€鑵烘縺绱犲強鎶楃敳鐙€鑵鸿棩銆佽儼宄剁礌鍙婂彛
鏈嶉檷琛€绯栬棩锛岃姹傝€冪敓鍦ㄥ厖鍒嗗京(f霉)缈�(x铆)鐩稿叢鐢熺悊瀛�(xu茅)鐭ヨ瓨(sh铆)鐨勫熀绀�(ch菙)涓婏紝鎺屾彙鐔熸倝濡備笅鍏�(n猫i)瀹广€�
1. 鑵庝笂鑵虹硸鐨唱(zh矛)婵€绱犵敓鐞嗘晥鎳�(y墨ng)鍙婅棩鐞嗕綔鐢�銆佷綔鐢ㄧ壒榛�(di菐n)銆佸垎椤�銆佽嚚搴婄敤钘ュ師鍓囧強鎸囧緛銆佺敤娉�
涓嶇敤閲忋€佷笇鑹弽鎳�(y墨ng)涓嶈棩鐗╂揩鐢ㄧ殑鍗卞锛岀毊璩�(zh矛)婵€绱犵殑妲�(g貌u)鏁堝叢绯诲懢浣滅敤姗�(j墨)鍒躲€�
2. 鐢茬媭鑵烘縺绱犵殑鐢熺墿鍚堟垚銆佸垎娉岃(di脿o)绡€(ji茅)锛屽懢鐢茬媭鑵虹礌鐨勮棩鐞嗕綔鐢ㄥ強鑷ㄥ簥鐢ㄩ€�锛屾姉鐢茬媭鑵鸿棩鐗�
鐨勪綔鐢ㄥ師鐞嗐€佽嚚搴婃噳(y墨ng)鐢�銆佷笇鑹弽鎳�(y墨ng)涓嶇敤钘ユ敞鎰忎簨闋�(xi脿ng)銆�
3. 鑳板扯绱犵殑闄嶈绯栦綔鐢ㄥ強閬╂噳(y墨ng)鐧ワ紱鍙ｆ湇闄嶈绯栬棩鐗╃敳鑻：涓佽劜銆佺敳绂忔槑鍙婅嫰涔欑鏄庣殑闄嶈
绯栦綔鐢ㄧ壒榛�(di菐n)銆佹噳(y墨ng)鐢�銆佷笇鑹弽鎳�(y墨ng)銆�
锛堝崄锛夊寲鐧傝棩鐗╄棩鐞嗗(xu茅)
鍖栫檪钘ョ墿钘ョ悊瀛�(xu茅)鍖呮嫭鎶楄弻钘ョ墿姒傝珫銆佄�-鍏�(n猫i)閰拌兒椤炴姉鐢熺礌銆佸ぇ鐠�(hu谩n)鍏�(n猫i)閰鎶楃敓绱�銆佹灄鍙�
闇夌礌鍙婂叾瀹冩姉鐢熺礌銆佹皑鍩虹敊椤炴姉鐢熺礌鍙婂绮樿弻绱�銆佸洓鐠�(hu谩n)绱犻鍙婃隘闇夌礌鎶楃敓绱�銆佷汉宸ュ悎鎴愭姉鑿�

钘�銆佹姉鐪熻弻鍙婃姉鐥呮瘨钘�銆佹姉绲�(ji茅)鏍哥梾钘ュ強鎶楅夯棰�(f膿ng)鐥呰棩銆佹姉鐦ц棩銆佹姉鑵歌爼锜茶棩銆佹姉闃跨背宸寸梾鍙婃姉
婊磋煵鐥呰棩銆佹姉鎯℃€ц叓鐦よ棩銆�
1. 鐔熸倝鎶楄弻钘ョ墿鐨勫父鐢ㄨ(sh霉)瑾�锛屽悇椤炶棩鐗╃殑鎶楄弻鍘熺悊鍙婄窗(x矛)鑿岀殑鑰愯棩鎬с€�
2. 鎺屾彙 尾-鍏�(n猫i)閰拌兒椤炴姉鐢熺礌鐨勬姉鑿屾(j墨)鍒�銆佸奖闊挎姉鑿屼綔鐢ㄥ洜绱犲強绱�(x矛)鑿岃€愯棩姗�(j墨)鍒�锛屾帉鎻￠潚闇夌礌涓�
鍗婂悎鎴愰潚闇夌礌鐨勬姉鑿岃瓬銆侀仼鎳�(y墨ng)璀�銆佷笇鑹弽鎳�(y墨ng)鍙婂叾闃叉不锛屾帉鎻￠潚闇夌礌鍛鹃牠瀛㈣弻绱犵殑鐧�(f膩)灞曟娉�锛�
鍒嗛鍙婂悇椤炶棩鐗╃壒榛�(di菐n)锛岀啛鎮夐潪鍏稿瀷 尾-閰拌兒椤炴姉鐢熺礌鐨勭壒榛�(di菐n)銆�
3. 鎺屾彙澶х挵(hu谩n)鍏�(n猫i)閰鎶楃敓绱犵殑鎶楄弻璀滃強鎶楄弻浣滅敤姗�(j墨)鍒�锛岀啛鎮夊ぇ鐠�(hu谩n)鍏�(n猫i)閰鎶楃敓绱犳瘡鍊�(g猫)钘ョ墿鐨勬姉
鑿岀壒榛�(di菐n)锛屾帉鎻＄磪闇夌礌銆佽惉鍙ら湁绱犲懢澶氱矘鑿岀礌鐨勬姉鑿岀壒榛�(di菐n)銆佷笇鑹弽鎳�(y墨ng)涓嶈嚚搴婃噳(y墨ng)鐢ㄣ€�
4. 鎺屾彙姘ㄥ熀鐢欓鎶楃敓绱犵殑鍏辨€э紙楂斿収(n猫i)閬庣▼銆佹姉鑿屼綔鐢�銆佹瘨鎬э級锛涙帉鎻℃叾澶ч湁绱�銆侀張闇夌礌鐨勬姉
鑿屼綔鐢�銆佽嚚搴婃噳(y墨ng)鐢ㄥ強涓岃壇鍙嶆噳(y墨ng)锛涚啛鎮夊叾瀹冭棩鐗╃殑浣滅敤鐗归粸(di菐n)銆�
5. 鎺屾彙鍥涚挵(hu谩n)绱犻銆佹隘闇夌礌椤炵殑鎶楄弻浣滅敤锛岃嚚搴婁綔鐢�锛屼笇鑹弽鎳�(y墨ng)鍙婂叾闃叉不锛屾帉鎻″瑗跨挵(hu谩n)绱�锛�
绫宠鐠�(hu谩n)绱犵殑鐗归粸(di菐n)銆�
6. 鎺屾彙鍠硅閰鍛剧：鑳洪钘ョ墿鐨勬姉鑿岃瓬锛岄珨鍏�(n猫i)閬庣▼锛岃嚚搴婃噳(y墨ng)鐢�锛屾帉鎻＄敳姘ц姁鍟剁殑浣滅敤姗�(j墨)鐞�
涓嶆噳(y墨ng)鐢�锛屼笉纾鸿兒椤炲悎鐢ㄧ殑鏍规摎(j霉)锛屾帉鎻＄鍩哄憢鍠冮钘ョ墿鐨勪綔鐢ㄧ壒榛�(di菐n)銆�
7. 鎺屾彙鎶楃湡鑿岃棩鐗╁叐鎬ч湁绱� B銆佸埗闇夎弻绱�銆佷笁鍞戦钘ョ墿銆佷紛鏇插悍鍞�銆佷紡绔嬪悍鍞戙€佸崱娉婅姮鍑�銆�
绫冲崱鑺噲鐨勪綔鐢ㄧ壒榛�(di菐n)锛屾帉鎻℃姉鐥呮瘨钘ョ墿鐨勪綔鐢ㄧ壒榛�(di菐n)銆�
8. 鎺屾彙涓€绶氭姉绲�(ji茅)鏍哥梾钘ワ細鐣扮厵鑲�銆佸埄绂忓钩銆佷箼鑳轰竵閱�銆侀張闇夌礌鎶楃祼(ji茅)鏍镐綔鐢ㄧ壒榛�(di菐n)銆佽€愯棩鎬�銆�
鑷ㄥ簥鎳�(y墨ng)鐢�銆佷笇鑹弽鎳�(y墨ng)鍙婄祼(ji茅)鏍哥梾鐨勯槻娌诲師鍓�锛涚啛鎮夋姉楹婚ⅷ(f膿ng)钘ワ細姘ㄨ嫰鐮溿€佸埄绂忓钩鐨勬姉楹婚ⅷ(f膿ng)浣滅敤銆�
鎳�(y墨ng)鐢ㄥ強姣掓€э紝鐔熸倝鎶楃祼(ji茅)鏍镐簩绶氳棩鍙婃姉楹婚ⅷ(f膿ng)鐥呰棩銆�
锛堝崄涓€锛夊奖闊垮厤鐤姛鑳界殑钘ョ墿
1. 鎺屾彙鍏嶇柅鎶戝埗钘ョ挵(hu谩n)瀛㈢礌銆佷粬鍙帿钁夈€侀浄甯曢湁绱�銆佽厧涓婅吅鐨唱(zh矛)婵€绱�銆佺挵(hu谩n)纾烽叞鑳�銆佺～鍞戝槍鍛�
鐨勪綔鐢ㄥ強姗�(j墨)鍒�锛岃棩鍕�(d貌ng)瀛�(xu茅)銆佽嚚搴婃噳(y墨ng)鐢ㄥ懢涓岃壇鍙嶆噳(y墨ng)銆�

2.鐔熸倝鍏嶇柅澧炲挤(qi谩ng)鍔戝崱浠嬭嫍銆佸乏鏃嬪挭鍞�銆佺櫧绱�(x矛)鑳炰粙绱�-2銆佽兏鑵鸿偨銆佸共鎿剧礌 鐨勪綔鐢ㄧ壒榛�(di菐n)銆�
浜� 鐢熺墿鍖栧(xu茅)
绗竴绔� 铔嬬櫧璩�(zh矛)鐨勭祼(ji茅)妲�(g貌u)鑸囧姛鑳�
1. 铔嬬櫧璩�(zh矛)鐨勫厓绱犵祫鎴愬強鐗归粸(di菐n)锛屾皑鍩洪吀鐨勭祼(ji茅)妲�(g貌u)閫氬紡锛屾皑鍩洪吀鐨勫垎椤�銆佷笁瀛楄嫳鏂囩府瀵鍙�銆�
2. 鑲姐€佽偨閸典笉鑲介張鐨勬蹇�锛屽鑲介張鐨勫娉�銆佽泲鐧借唱(zh矛)涓€绱�(j铆)绲�(ji茅)妲�(g貌u)鐨勬蹇靛強鍏朵富瑕佺殑鍖栧(xu茅)閸�銆�
3. 鑲藉柈鍏�銆佽秴浜岀礆(j铆)绲�(ji茅)妲�(g貌u)銆佹ā楂旀蹇�銆佽泲鐧借唱(zh矛)鐨勪簩绱�(j铆)绲�(ji茅)妲�(g貌u)鐨勬蹇�銆佷富瑕佸寲瀛�(xu茅)閸靛懢褰㈠紡銆�
4. 铔嬬櫧璩�(zh矛)鐨勪笁绱�(j铆)绲�(ji茅)妲�(g貌u)姒傚康鍛剧董鎸佸叾绌�(w臎n)瀹氱殑鍖栧(xu茅)閸�銆佺祼(ji茅)妲�(g貌u)鍩熸蹇�銆�
5. 铔嬬櫧璩�(zh矛)鐨勫洓绱�(j铆)绲�(ji茅)妲�(g貌u)鐨勬蹇靛懢缍寔绌�(w臎n)瀹氱殑鍖栧(xu茅)閸�銆�
6. 铔嬬櫧璩�(zh矛)鐨勭祼(ji茅)妲�(g貌u)涓嶅姛鑳界殑鍏茬郴锛氫竴绱�(j铆)绲�(ji茅)妲�(g貌u)姹哄畾绌洪枔绲�(ji茅)妲�(g貌u)锛岀┖闁撶祼(ji茅)妲�(g貌u)姹哄畾鐢熺墿瀛�(xu茅)鍔熻兘銆�
7. 铔嬬櫧璩�(zh矛)鐨勭悊鍖栨€ц唱(zh矛)锛氬叐鎬ч浕闆�锛岃啝楂旀€ц唱(zh矛)锛岃泲鐧借唱(zh矛)璁婃€х殑姒傚康鍛炬剰缇╋紝绱鍚告敹鍛惧憟鑹�
鍙嶆噳(y墨ng)銆�
8. 铔嬬櫧璩�(zh矛)鍒嗛洟鍛剧磾鍖栨妧琛�(sh霉)锛氳秴婵�銆侀菇鏋愩€侀浕娉冲懢闆㈠績鐨勫師鐞�锛涘鑲介張涓皑鍩洪吀搴忓垪鍒嗘瀽鐨�
鍘熺悊锛涜泲鐧借唱(zh矛)绌洪枔绲�(ji茅)妲�(g貌u)闋�(y霉)娓�(c猫)鐨勫師鐞嗗懢鎰忕京銆�
绗簩绔� 鏍搁吀鐨勭祼(ji茅)妲�(g貌u)鑸囧姛鑳�
1. 鏍歌嫹閰哥殑绲�(ji茅)妲�(g貌u)銆佺鍙靛懢鎬ц唱(zh矛)銆丏NA 鍛� RNA 鐨勫垎瀛愮祫鎴�銆佹牳閰稿垎瀛愪腑鏍歌嫹閰哥殑閫ｆ帴鏂卞紡銆�
鍖栧(xu茅)閸�銆佹牳閰哥殑涓€绱�(j铆)绲�(ji茅)妲�(g貌u)鍙婂叾琛ㄧず娉曘€�
2. DNA 鐨勪簩绱�(j铆)绲�(ji茅)妲�(g貌u)鐨勭壒榛�(di菐n)銆丏NA 鐨勭敓鐗╁(xu茅)鍔熻兘銆佸師鏍哥敓鐗� DNA 鐨勮秴铻烘棆绲�(ji茅)妲�(g貌u)锛岀湡鏍哥敓鐗�
鏌撹壊楂旂殑鍩烘湰鍠綅---鏍稿皬楂旂殑绲�(ji茅)妲�(g貌u)銆�
3. RNA 鐨勭ó椤炰笉鍔熻兘锛氫俊浣� RNA 鍛捐綁(zhu菐n)閬�(y霉n) RNA 鐨勭祼(ji茅)妲�(g貌u)鐗归粸(di菐n)銆乼RNA 浜岀礆(j铆)绲�(ji茅)妲�(g貌u)鐨勭壒榛�(di菐n)涓嶅姛鑳姐€�
4. DNA 鐨勮畩鎬у懢寰�(f霉)鎬ф蹇靛懢鐗归粸(di菐n)锛岃В閺堟洸绶氫笉 Tm銆佹牳閰稿垎瀛愰洔浜ゅ師鐞嗐€�
绗笁绔� 閰�
1. 閰剁殑姒傚康锛岄叾鐨勫寲瀛�(xu茅)鏈唱(zh矛)銆侀叾鐨勫垎瀛愮祫鎴�锛屽柈绱旈叾鍛惧叏閰�銆侀叾鐨勬椿鎬т腑蹇冪殑姒傚康銆佸繀闇€

鍩哄湗(tu谩n)鐨勫垎椤炲強鍏朵綔鐢�銆佸悓宸ラ叾鐨勬蹇靛懢鐢熺悊鎰忕京銆�
2. 閰朵績鍙嶆噳(y墨ng)鐨勭壒榛�(di菐n)銆侀叾淇冧綔鐢ㄧ殑姗�(j墨)鍒�銆�
3. 搴曠墿婵冨害銆侀叾婵冨害銆佹韩搴︺€乸H銆佹縺娲诲姂灏�(du矛)閰朵績鍙嶆噳(y墨ng)鐨勫奖闊�銆佺背锛嶆浖姘忔柋绋嬶紝Km 涓� Vmax
鍊肩殑鎰忕京銆佹姂鍒跺姂灏�(du矛)閰朵績鍙嶆噳(y墨ng)鐨勫奖闊裤€佷笇鍙€嗘€ф姂鍒剁殑浣滅敤銆佸彲閫嗘€ф姂鍒剁殑鍕�(d貌ng)鍔涘(xu茅)鐗瑰緛鍙婂叾
鐢熺悊瀛�(xu茅)鎰忕京銆�
4. 鍒ユ(g貌u)閰跺懢鍒ユ(g貌u)瑾�(di脿o)绡€(ji茅)鐨勬蹇�銆佹(j墨)鐞嗐€侀叾鐨勫寲瀛�(xu茅)淇＞銆侀叾鍘熶笉閰跺師婵€娲荤殑閬庣▼涓嶇敓鐞嗘剰缇┿€�
5. 閰跺湪鐤剧梾鐧�(f膩)鐢�銆佺柧鐥呰ê鏂�銆佺柧鐥呮不鐧備腑鐨勬噳(y墨ng)鐢ㄣ€�
绗簩绡� 鐗╄唱(zh矛)浠ｈ瑵鍙婂叾瑾�(di脿o)绡€(ji茅)
绗叚绔� 绯栦唬璎�
1. 绯栫殑鐒℃哀鍒嗚В鐨勬蹇�銆侀檺閫熼叾銆丄TP 鐢熸垚銆佷綔鐢ㄩ儴浣嶅強鐢熺悊鎰忕京銆�
2. 绯栫殑鏈夋哀姘у寲姒傚康銆侀殠娈�锛岀硸鐨勬湁姘ф哀鍖栭€斿緫涓笝閰吀姘у寲鑴晶鍙婁笁缇ч吀寰挵(hu谩n)鐨勫熀鏈弽
鎳�(y墨ng)閬庣▼銆侀檺閫熼叾銆丄TP 鐢熸垚銆佷綔鐢ㄩ儴浣嶅強鐢熺悊鎰忕京銆�
3. 纾烽吀鎴婄硸閫斿緫鐨勭敓鐞嗘剰缇�锛孨ADPH 鐨勫姛鑳�銆�
4. 绯栧師鍚堟垚鍙婂垎瑙ｇ殑鍩烘湰鍙嶆噳(y墨ng)閬庣▼銆侀儴浣�銆佸叢閸甸叾锛岃(di脿o)绡€(ji茅)鍙婄敓鐞嗘剰缇╋紝绯栧師鍚堟垚鐨勯亷绋嬩腑
UDPG 鐨勭敓鎴愬懢浣滅敤銆�
5. 绯栫暟鐢熺殑姒傚康銆侀檺閫熼叾鍙婂叾鍌寲鐨勫弽鎳�(y墨ng)鍛剧敓鐞嗘剰缇┿€佷钩閰稿惊鐠�(hu谩n)鍙婂叾鐢熺悊鎰忕京銆�
6. 姝ｅ父浜鸿绯栫殑渚嗘簮涓嶅幓璺€佽绯栨績搴︾殑瑾�(di脿o)绡€(ji茅)鏂卞紡銆�
绗竷绔� 鑴傞浠ｈ瑵
1. 鑴傝偑鍕�(d貌ng)鍝＄殑姒傚康鍛鹃檺閫熼叾锛岃剛鑲吀鐨� 尾锛嶆哀鍖栨蹇�锛岃剛閰哥殑娲诲寲銆佽剛閰� CoA 閫�(j矛n)鍏ョ窔绮掗珨銆�
鑴傞吀 尾锛嶆哀鍖栫殑鑴矮銆佸姞姘淬€佸啀鑴矮鍛剧～瑙ｇ瓑姝ラ锛岃剛鑲吀姘у寲閬庣▼涓兘閲忕殑瑷�(j矛)绠�銆�
2. 鐢樻补涓夐叝鐨勫悎鎴愪唬璎濓細閮ㄤ綅銆佸悎鎴愬師鏂欏懢鍚堟垚閬庣▼锛岃剛鑲吀鐨勫悎鎴愶細鍘熸枡銆侀儴浣嶅懢闄愰€�
閰�锛岃剛鑲吀鍚堟垚閰剁殑鐗归粸(di菐n)锛屾縺绱犲皪(du矛)鑴傞吀鍚堟垚鐨勮(di脿o)绡€(ji茅)銆�

3. 閰珨鐨勬蹇�锛岄叜楂旂殑鐢熸垚鍛惧埄鐢ㄧ殑閮ㄤ綅銆侀叜楂旂敓鎴愮殑鐢熺悊鎰忕京銆�
4. 鐢樻补纾疯剛鐨勭祫鎴�銆佸垎椤炲懢绲�(ji茅)妲�(g貌u)銆佺敇娌圭７鑴傜殑鍚堟垚閫斿緫锛氱敇娌逛簩閰悎鎴愰€斿緫鍛� CDP-鐢樻补浜�
閰悎鎴愰€斿緫锛涚敇娌圭７鑴傜殑闄嶈В锛氱７鑴傞叾椤炲皪(du矛)鐢樻补纾烽叝鐨勬按瑙ｅ強鐢�(ch菐n)鐗╃殑浣滅敤銆�
5 .鑶藉浐閱囩殑鍚堟垚锛氶儴浣嶃€佸悎鎴愬師鏂欏懢闄愰€熼叾銆佽綁(zhu菐n)鍖栫敘(ch菐n)鐗�銆�
6. 琛€婕胯剛铔嬬櫧鐢ㄩ浕娉虫硶鍛捐秴閫熼洟蹇冩硶鐨勫垎椤�銆佷富瑕佺祫鎴愭垚鍒嗗懢鍔熻兘銆佽級鑴傝泲鐧界殑鍔熻兘锛屾煇
浜涜級鑴傝泲鐧藉皪(du矛)鑴傝偑閰舵椿鎬х殑婵€娲讳綔鐢�銆佽婕胯剛铔嬬櫧浠ｈ瑵鐣板父銆�
绗叓绔� 鐢熺墿姘у寲
1. 鐢熺墿姘у寲鐨勬蹇靛強鐢熺悊鎰忕京銆�
2. 鍛煎惛閺堢殑姒傚康銆佺窔绮掗珨鐨勫叐姊濆懠鍚搁張---NADH 姘у寲鍛煎惛閺堝懢鐞ョ弨閰告哀鍖栧懠鍚搁張鐨勭祫鎴愭垚
鍒嗗懢鎺掑垪闋嗗簭銆�
3. 姘у寲纾烽吀鍖栫殑姒傚康鍙婃哀鍖栫７閰稿寲鐨勫伓鑱�(li谩n)閮ㄤ綅銆丄TP 涓嶈兘閲忛噵鏀俱€佽帛瀛樺懢鍒╃敤锛岀７閰搁吀鑲�
閰告槸楂樿兘纾烽吀鍩哄湗(tu谩n)鐨勮帛瀛樺舰寮�銆�
4. 褰遍熆姘у寲纾烽吀鍖栫殑鍥犵礌鍛惧懠鍚搁張鐨勬姂鍒跺姂銆佽В鍋惰伅(li谩n)鍔�锛岀敳鐙€鑵烘縺绱犲皪(du矛)姘у寲纾烽吀鍖栫殑褰遍熆銆�
5. 鑳炴恫涓� NADH 姘у寲鐨勫叐绋綁(zhu菐n)閬�(y霉n)姗�(j墨)鍒讹細伪-纾烽吀鐢樻补绌挎鍙婅構鏋滈吀澶╁啲姘ㄩ吀绌挎鐨勮兘閲�銆侀儴
浣嶅樊鐣�銆�
绗節绔� 姘ㄥ熀閰镐唬璎�
1. 鐕熼(y菐ng)蹇呴渶姘ㄥ熀閰哥殑姒傚康銆佺ó椤�銆佹爱骞宠　鐨勬蹇靛懢椤炲瀷锛岃泲鐧借唱(zh矛)鐨勯渶瑕侀噺鍛剧嚐椁�(y菐ng)鍍�(ji脿)鍊�銆�
2. 鑳拌泲鐧介叾绛夎泲鐧介叾灏�(du矛)铔嬬櫧璩�(zh矛)鐨勬按瑙ｄ綔鐢�锛屽皬鑵镐腑姘ㄥ熀閰稿懢鑲界殑鍚告敹姗�(j墨)鍒�锛岃泲鐧借唱(zh矛)鍦ㄥ皬鑵�
鐨勮厫鏁椾綔鐢ㄣ€�
3. 姘ㄥ熀閰哥殑鑴皑鍩轰綔鐢細鑱�(li谩n)鍚堣劔姘ㄥ熀浣滅敤銆佽綁(zhu菐n)姘ㄥ熀浣滅敤銆丩-璋锋皑閰告哀鍖栬劔姘ㄥ熀浣滅敤鐨勬蹇�銆�
浣滅敤姗�(j墨)鍒�锛浳�-閰吀鐨勪唬璎濆幓璺紝鐢熺硸姘ㄥ熀閰�銆佺敓閰皑鍩洪吀銆佺敓绯栧吋鐢熼叜姘ㄥ熀閰哥殑姒傚康銆�
4. 姘ㄧ殑渚嗘簮涓嶅幓璺�銆佹皑鐨勮綁(zhu菐n)閬�(y霉n)褰㈠紡銆佸翱绱犲悎鎴愮殑閮ㄤ綅銆侀偿姘ㄩ吀寰挵(hu谩n)鐨勪富瑕侀€斿緫鍛剧敓鐞嗘剰缇�銆�

灏跨礌鍚堟垚鐨勮(di脿o)绡€(ji茅)锛岄珮琛€姘ㄧ櫏鍛炬皑涓瘨銆�
5. 涓€纰冲柈浣嶇殑姒傚康銆佷竴纰冲柈浣嶇殑渚嗘簮銆佽級楂斻€佺ó椤炲懢鐢熺悊鎰忕京銆�
6. 鍚～姘ㄥ熀閰哥殑浠ｈ瑵锛氱敳鍩虹殑鐩存帴渚涢珨锛圫-鑵鸿嫹鐢茬～姘ㄩ吀锛夈€佺敳纭皑閰稿惊鐠�(hu谩n)銆佺～閰告牴鐨勬椿鎬�
褰㈠紡锛圥APS锛夈€佽倢閰哥殑鍚堟垚銆�
7. 鑺抽鏃忔皑鍩洪吀鐨勪唬璎濓細鑻笝姘ㄩ吀鍛鹃叒姘ㄩ吀鐨勪唬璎濈敘(ch菐n)鐗╋紝鍊�(g猫)鍒ユ皑鍩洪吀浠ｈ瑵涓嚭鐝�(xi脿n)鐨勮嚚搴婄己
涔忕櫏銆�
绗崄绔� 鏍歌嫹閰镐唬璎�
1. 鍢屽懁鏍歌嫹閰稿悎鎴愮殑鍏╃ó閫斿緫---寰為牠鍚堟垚閫斿緫鍙婅(b菙)鏁戝悎鎴愰€斿緫鐨勫師鏂欍€佷富瑕佹椹熷強鐗归粸(di菐n)銆�
2. 鍢屽懁鏍歌嫹閰哥殑鍒嗚В浠ｈ瑵鐨勭祩鐢�(ch菐n)鐗╋紝灏块吀涓嶇棝棰�(f膿ng)鐧ョ殑鍏茬郴銆�
3. 鍢у暥鏍歌嫹閰稿悎鎴愮殑鍏╃ó閫斿緫---寰為牠鍚堟垚閫斿緫鍙婅(b菙)鏁戝悎鎴愰€斿緫鐨勫師鏂�銆佷富瑕佹椹熷強鐗归粸(di菐n)銆�
4. 鍢у暥鏍歌嫹閰哥殑鍒嗚В浠ｈ瑵鐨勭祩鐢�(ch菐n)鐗�銆�
5. 鑴哀鏍歌嫹閰哥殑鐢熸垚銆�
6. 鍢屽懁銆佸槯鍟舵牳鑻烽吀鐨勬姉浠ｈ瑵鐗╁強鍏舵姉鑵槫浣滅敤鐨勭敓鍖栨(j墨)鐞�銆�
绗崄涓€绔� 闈炵嚐椁�(y菐ng)鐗╄唱(zh矛)浠ｈ瑵
1. 鐢熺墿杞�(zhu菐n)鍖栫殑姒傚康銆佷富瑕佸櫒瀹樸€佹剰缇╁強鐢熺墿杞�(zhu菐n)鍖栧弽鎳�(y墨ng)鐨勪富瑕侀鍨�锛岀涓€鐩稿弽鎳�(y墨ng)鐨勬蹇�銆佺
浜岀浉鍙嶆噳(y墨ng)鐨勬蹇靛強閲嶈鐨勭祼(ji茅)鍚堝姂銆佺敓鐗╄綁(zhu菐n)鍖栫殑褰遍熆鍥犵礌銆�
2. 鑶芥眮閰哥殑鍒嗛銆佸垵绱�(j铆)鍛炬绱�(j铆)鑶芥眮閰哥殑姒傚康銆佽喗姹侀吀鐨勮吀鑲濆惊鐠�(hu谩n)鍙婄敓鐞嗘剰缇�銆�
3. 鑶界磪绱犵殑渚嗘簮鍛剧敓鎴�銆佹湭绲�(ji茅)鍚堣喗绱呯礌鍦ㄨ涓殑閬�(y霉n)杓搞€佽倽绱�(x矛)鑳炲皪(du矛)鑶界磪绱犵殑鏀濆彇涓嶈綁(zhu菐n)鍖栵紙绲�(ji茅)
鍚堬級銆佺祼(ji茅)鍚堣喗绱呯礌鐨勬帓娉勩€佽喗绱呯礌鍦ㄨ吀閬撲腑鐨勮綁(zhu菐n)鍖栦笉鎺掓硠銆佽喗绱犲師鐨勮吀鑲濆惊鐠�(hu谩n)銆佸翱鑶界礌鍘熺殑
鎺掓硠绛夎喗鑹茬礌浠ｈ瑵閬庣▼銆�
4. 鑶借壊绱犱唬璎濅笉榛冪柛锛氳娓呰喗绱呯礌銆侀珮鑶界磪绱犺鐧ュ強榛冪柛鐨勬蹇�锛屼笁绋粌鐤哥殑鑶借壊绱犱唬璎�
鐣板父鐨勭壒榛�(di菐n)锛岄珮鑶界磪绱犺鐧ョ殑涓夌ó鍘熷洜鍙婅娓呰喗绱呯礌涓嶉粌鐤�銆�

绗笁绡� 閬哄偝淇℃伅鐨勫偝閬�
绗崄鍥涚珷 DNA 鐨勭敓鐗╁悎鎴�
1. DNA 寰�(f霉)鍒剁殑鍩烘湰鐗瑰緛锛屽崐淇濈暀寰�(f霉)鍒剁殑姒傚康鍛炬剰缇�锛屽墠灏�(d菐o)閺�銆侀毃寰為張銆佸病宕庣墖娈电殑姒傚康銆�
2. DNA 鑱氬悎閰剁殑绋涓嶄綔鐢ㄣ€佽В铻烘棆閰�銆丏NA 鎷�?f霉)娲氭偐?g貌u)閰�銆佸柈閺� DNA 绲�(ji茅)鍚堣泲鐧藉湪 DNA
寰�(f霉)鍒朵腑鐨勪富瑕佷綔鐢紝寰�(f霉)鍒剁殑淇濈湡鎬�銆�
3. 寰�(f霉)鍒剁殑璧峰銆佸欢闀�銆佺祩姝㈤亷绋嬶細寰�(f霉)鍒惰捣濮嬮粸(di菐n)锛岃В閺堣В鏃�锛屽紩鐧�(f膩)楂斿強寮曠墿鐨勭敓鎴愩€佸病宕庣墖
娈电殑鐢熸垚銆侀€ｆ帴閰剁殑浣滅敤锛涚湡鏍哥敓鐗╁京(f霉)鍒剁殑鐗归粸(di菐n)锛岀绮掍笉绔矑閰剁殑姒傚康鍛剧祼(ji茅)妲�(g貌u)绲勬垚鍙婄绮掍笉
绱�(x矛)鑳炵敓闀�銆佽叓鐦ゅ舰鎴愮殑鍏茬郴銆�
4. 閫嗚綁(zhu菐n)閷勭殑姒傚康銆侀€嗚綁(zhu菐n)閷勯叾鐨勪綔鐢�銆�
5. DNA 鎼嶅偡鐨勫洜绱�銆丏NA 鎼嶅偡鐨勯鍨�銆佹悕鍌蜂慨寰�(f霉)姗�(j墨)鍒�銆�
绗崄鍏珷 RNA 鐨勭敓鐗╁悎鎴�
1. 寰�(f霉)鍒朵笉杞�(zhu菐n)閷勭殑鍗€(q奴)鍒�锛屼笇灏�(du矛)绋辫綁(zhu菐n)閷勩€佹ā鏉块張鍛剧法纰奸張鐨勬蹇�銆�
2. 鍘熸牳鐢熺墿鐨� RNA 鑱氬悎閰跺強鍏朵簽鍩虹祫鎴愬強 RNA 鑱氬悎閰剁祼(ji茅)鍚堢殑閮ㄤ綅銆�
3. 鍘熸牳鐢熺墿杞�(zhu菐n)閷勭殑璧峰銆佸欢闀�銆佺祩姝㈤亷绋嬶細杞�(zhu菐n)閷勮捣濮嬪京(f霉)鍚堢墿銆佽綁(zhu菐n)閷勭┖娉★紙杞�(zhu菐n)閷勫京(f霉)鍚堢墿锛夌殑
姒傚康鍙婂叾褰㈡垚锛屜� 鍥犲瓙鐨勪綔鐢�锛屽師鏍哥敓鐗╄綁(zhu菐n)閷勭祩姝㈢殑鍏╃ó鏂卞紡锛堜緷璩� Rho 鍥犲瓙鐨勮綁(zhu菐n)閷勭祩姝�
鍙婁笇渚濊炒 Rho 鍥犲瓙鐨勮綁(zhu菐n)閷勭祩姝級姗�(j墨)鍒躲€�
4. 鐪熸牳鐢熺墿鐨� RNA 鑱氬悎閰剁ó椤�銆佸姛鑳斤紝鐪熸牳鐢熺墿涓嶅師鏍哥敓鐗╄綁(zhu菐n)閷勯亷绋嬬殑鐣板悓銆�
5. 鐪熸牳 mRNA 鐢熺墿杞�(zhu菐n)閷勫悗鍔犲伐閬庣▼锛氬椤瓙銆佸収(n猫i)鍚瓙鐨勬蹇�锛屽姞甯姐€佸姞灏�銆乵RAN 鍓嶉珨
鐨勫壀鎺ャ€丷NA 绶ㄨ集銆�
绗崄涓冪珷 铔嬬櫧璩�(zh矛)鐨勭敓鐗╁悎鎴�
1. mRNA銆乼RNA銆乺RNA 鍦ㄧ炕璀亷绋嬩腑鐨勪綔鐢�銆�
2. 閬哄偝瀵嗙⒓锛堝瘑纰煎瓙锛夌殑姒傚康鍙婂叾鐗归粸(di菐n)銆佸瘑纰煎瓙鍛惧弽瀵嗙⒓瀛愮殑鍏茬郴銆佹牳绯栭珨 A 浣嶃€丳 浣�銆丒

浣嶇殑浣滅敤銆佹皑鍩洪叞-tRNA 鍚堟垚閰剁殑浣滅敤銆�
3. 鍘熸牳鐢熺墿缈昏鐨勮捣濮嬨€佽偨閺堢殑寤堕暦銆佽偨閺堢殑绲傛閬庣▼锛氭皑鍩洪吀鐨勬椿鍖栦笉杞�(zhu菐n)閬�(y霉n)銆佺炕璀捣濮�
寰�(f霉)鍚堢墿鐨勫舰鎴愩€佽偨閺堢殑寤堕暦锛堜笁鍊�(g猫)寰挵(hu谩n)姝ラ锛�銆佽偨閺堝悎鎴愮殑绲傛锛堢祩姝㈠洜瀛愶級鍙婂鑱氭牳绯栭珨
鐨勬蹇点€�
4. 缈昏鍚庣殑鍔犲伐鏂卞紡銆�
5. 骞剧ó鎶楃敓绱犲皪(du矛)缈昏鐨勬姂鍒朵綔鐢�锛屾煇浜涙瘨绱犺泲鐧界殑浣滅敤姗�(j墨)鐞�銆佸共鎿剧礌鎶楃梾姣掍綔鐢ㄦ(j墨)鐞嗐€�
绗崄鍏珷 鍩哄洜琛ㄩ仈(d谩)瑾�(di脿o)鎺�
1. 鍩哄洜琛ㄩ仈(d谩)瑾�(di脿o)鎺х殑鐗归粸(di菐n)鍙婄浉鍏叉蹇碉細鍩哄洜琛ㄩ仈(d谩)銆佸熀鍥犺〃閬�(d谩)瑾�(di脿o)鎺с€佺祫鎴愭€у熀鍥犺〃閬�(d谩)銆佽獦灏�(d菐o)鍛�
闃婚亸鐨勬蹇碉紱鍩哄洜琛ㄩ仈(d谩)瑾�(di脿o)鎺х殑鐢熺墿瀛�(xu茅)鎰忕京銆�
2. 涔崇硸鎿嶇副瀛愯(di脿o)绡€(ji茅)姗�(j墨)鍒讹細涔崇硸鎿嶇副瀛愮殑绲�(ji茅)妲�(g貌u)锛岄樆閬忚泲鐧界殑璨�(f霉)鎬ц(di脿o)绡€(ji茅)锛孋AP 鐨勬鎬ц(di脿o)绡€(ji茅)锛屽崝(xi茅)
瑾�(di脿o)瑾�(di脿o)绡€(ji茅)銆�
3. 鐪熸牳鍩哄洜绲勭祼(ji茅)妲�(g貌u)鐗归粸(di菐n)锛岀湡鏍稿熀鍥犺〃閬�(d谩)瑾�(di脿o)绡€(ji茅)鐗归粸(di菐n)锛屽暉鍕�(d貌ng)瀛�銆佸寮�(qi谩ng)瀛愩€佹矇榛樺瓙銆侀爢寮忎綔鐢ㄥ厓
浠跺懢鍙嶅紡浣滅敤鍥犲瓙鐨勬蹇靛懢浣滅敤銆�
绗洓绡� 鍒嗗瓙閱�(y墨)瀛�(xu茅)灏堥
绗簩鍗佷竴绔� DNA 閲嶇祫鍙婇噸绲� DNA 鎶€琛�(sh霉)
1. 鍩哄洜閲嶇祫鍛鹃噸绲� DNA 鎶€琛�(sh霉)鐩稿叢姒傚康銆侀噸绲� DNA 鎶€琛�(sh霉)閲嶈鐨勫伐鍏烽叾锛孌NA 鍏嬮殕銆侀檺鍒�
鎬ф牳閰稿収(n猫i)鍒囬叾銆乧DNA銆佸熀鍥犵祫 DNA銆佽仛鍚堥叾閺堝弽鎳�(y墨ng)銆佸熀鍥犺級楂斻€侀檺鍒舵€ф牳閰稿収(n猫i)鍒囬叾鐨勭ó
椤炲強浣滅敤鐗归粸(di菐n)銆�
2. 閲嶇祫 DNA 鎶€琛�(sh霉)鐨勫熀鏈師鐞�銆佷竴鑸椹燂細鐩殑鍩哄洜鐨勭嵅鍙栥€佸厠闅嗚級楂旂殑閬告搰鍛炬(g貌u)寤�銆佸
婧愬熀鍥犱笉杓夐珨鐨勯€ｆ帴銆侀噸绲� DNA 灏�(d菐o)鍏ュ彈楂旂窗(x矛)鑳�銆侀噸绲勯珨鐨勭閬稿強鍏嬮殕鍩哄洜鐨勮〃閬�(d谩)銆�
3. 閲嶇祫 DNA 鎶€琛�(sh霉)鍦ㄩ啱(y墨)瀛�(xu茅)涓殑鎳�(y墨ng)鐢�銆�