|
鍙嬫儏鎻愮ず锛氭湰绔欐彁渚涘叏鍦�(gu贸)400澶氭墍楂樼瓑闄㈡牎鎷涙敹纰╁＋銆佸崥澹爺绌剁敓鍏ュ(xu茅)鑰冭│姝峰勾鑰冪爺鐪熼銆佽€冨崥鐪熼銆佺瓟妗�锛岄儴鍒嗗(xu茅)鏍℃洿鏂拌嚦2012骞�锛�2013骞�锛涘潎鎻愪緵鏀惰不(f猫i)涓嬭級銆� 涓嬭級娴佺▼锛� 鑰冪爺鐪熼 榛�(di菐n)鎿娾€�鑰冪爺瑭﹀嵎鈥濃€濅笅杓�; 鑰冨崥鐪熼 榛�(di菐n)鎿娾€�鑰冨崥瑭﹀嵎搴�(k霉)鈥� 涓嬭級
绂� 宸� 澶� 瀛�(xu茅)
2017 骞寸ⅸ澹爺绌剁敓鍏ュ(xu茅)鑰冭│灏�(zhu膩n)妤�(y猫)瑾茶绋嬶紙鑰冭│锛夊ぇ缍�
涓€銆佽€冭│绉戠洰鍚嶇ū(ch膿ng): 鐢熺墿鍖栧(xu茅)
浜�銆佹嫑鐢熷(xu茅)闄紙钃嬪(xu茅)闄㈠叕绔狅級锛� 鐢熺墿鍜岄啱(y墨)钘ユ妧琛�(sh霉)鐮旂┒闄�
鍩烘湰鍏�(n猫i)瀹�:
1. 鎺屾彙甯歌(ji脿n)鍠硸銆佸绯栧拰澶氱硸鐨勭祼(ji茅)妲�(g貌u)銆佹€ц唱(zh矛)鍙婄壒榛�(di菐n)銆�
2. 鎺屾彙娌硅剛銆佺７鑴�銆佸浐閱�銆侀(l猫i)鍥洪唶鍙婂叾浠栭叝椤�(l猫i)鐨勭壒榛�(di菐n)鍜屾€ц唱(zh矛)锛涚敓鐗╄啘鐨勫寲瀛�(xu茅)绲勬垚銆佺祼(ji茅)
妲�(g貌u)鍙婂姛鑳姐€�
3. 鎺屾彙姘ㄥ熀閰哥殑绲�(ji茅)妲�(g貌u)鐗归粸(di菐n)銆佽偨鐨勭祼(ji茅)妲�(g貌u)銆佽泲鐧借唱(zh矛)鐨勪竴绱�(j铆)銆佷簩绱�(j铆)鍙婇珮绱�(j铆)绲�(ji茅)妲�(g貌u)銆佽泲鐧借唱(zh矛)绲�(ji茅)妲�(g貌u)
鑸囧姛鑳界殑闂�(gu膩n)绯�銆佽泲鐧借唱(zh矛)鐨勬€ц唱(zh矛)銆佽泲鐧借唱(zh矛)鐨勮畩鎬т綔鐢�銆佽泲鐧借唱(zh矛)鐨勫垎闆€€佺磾鍖栬垏娓�(c猫)瀹�銆�
4. 鎺屾彙鏍搁吀锛圖NA 鑸� RNA锛夌殑姒傚康銆佹牳閰哥殑浜岀礆(j铆)銆佷笁绱�(j铆)绲�(ji茅)妲�(g貌u)鍙婂姛鑳�銆佹牳閰哥殑鎬ц唱(zh矛)銆佹牳閰�
鍙婂叾绲勫垎鐨勫垎闆㈢磾鍖�銆佹牳閰哥殑鍒嗘瀽娓�(c猫)瀹氬強鐮旂┒鏂规硶銆�
5. 鎺屾彙閰剁殑姒傚康銆佺壒榛�(di菐n)鍙婄祫鎴�銆侀叾鐨勭祼(ji茅)妲�(g貌u)鑸囧姛鑳界殑闂�(gu膩n)绯汇€侀叾淇冨弽鎳�(y墨ng)鐨勫嫊(d貌ng)鍔涘(xu茅)銆佸奖闊块叾
浣滅敤鐨勫洜绱�銆侀叾娲诲姏鐨勬脯(c猫)瀹�銆侀叾鐨勫妯ｆ€�銆�
6. 鎺屾彙铔嬬櫧璩�(zh矛)鍚堟垚楂旂郴銆侀伜鍌冲瘑纰�銆佽泲鐧借唱(zh矛)鐨勫悎鎴愭(j墨)鍒�銆佽泲鐧借唱(zh矛)鍚堟垚鐨勬姂鍒朵綔鐢�銆�
7. 鎺屾彙绱�(x矛)鑳炰俊铏�(h脿o)鐨勯(l猫i)鍒ュ強鐗归粸(di菐n)銆佺窗(x矛)鑳炰俊铏�(h脿o)鍙楅珨銆佸父瑕�(ji脿n)淇¤櫉(h脿o)杞�(zhu菐n)灏�(d菐o)閫斿緫锛坈AMP-PKA锛�銆�
8. 鎺屾彙鍩哄洜宸ョ▼鐨勬蹇�銆佸熀鍥犲伐绋嬬殑鍩烘湰姝ラ銆佽泲鐧借唱(zh矛)宸ョ▼銆�
鍙冭€冩浉(sh奴)鐩�(闋堣垏灏�(zhu膩n)妤�(y猫)鐩寗涓€鑷�)(鍖呮嫭浣滆€�銆佹浉(sh奴)鐩�銆佸嚭鐗堢ぞ銆佸嚭鐗堟檪(sh铆)闁撱€佺増娆�)锛�
銆婄敓鐗╁寲瀛�(xu茅)鏁欑▼銆嬬涓夌増锛屽嫉娲返绶�锛屽洓宸濆ぇ瀛�(xu茅)鍑虹増绀�锛�2002.4
瑾�(shu艒)鏄庯細1銆佽€冭│鍩烘湰鍏�(n猫i)瀹癸細涓€鑸寘鎷熀绀�(ch菙)鐞嗚珫銆佸(sh铆)闅涚煡璀�(sh铆)銆佺稖鍚堝垎鏋愬拰璜栬瓑绛夊咕鍊�(g猫)鏂归潰鐨勫収(n猫i)瀹�銆傛湁浜涜绋�
閭勬噳(y墨ng)鏈夊熀鏈亱(y霉n)绠楀拰瀵�(sh铆)椹�(y脿n)鏂规硶绛夋柟闈㈢殑鍏�(n猫i)瀹�銆傚瓧?j菒n)?sh霉)涓€鑸湪 300 瀛楀乏鍙�銆�
2銆侀洠鏄撶▼搴︼細鏍规摎(j霉)澶у(xu茅)鏈鐨勬暀瀛�(xu茅)澶х侗鍜屾湰瀛�(xu茅)绉�銆佸皥(zhu膩n)妤�(y猫)鐨勫熀鏈姹�锛屼竴鑸噳(y墨ng)浣垮ぇ瀛�(xu茅)鏈鐣㈡キ(y猫)鐢熶腑鍎�(y艒u)绉€瀛�(xu茅)
鐢熷湪瑕�(gu墨)瀹氱殑涓夊€�(g猫)灏忔檪(sh铆)鍏�(n猫i)绛斿畬鍏ㄩ儴鑰冮锛岀暐鏈変竴浜涙檪(sh铆)闁撻€�(j矛n)琛屾鏌ュ拰鎬濊€�銆傛帓搴忓緸鏄撳埌闆�銆�
鍏嶈铂(z茅)鑱叉槑锛氭湰鏂囩郴杞�(zhu菐n)杓夎嚜缍�(w菐ng)绲�(lu貌)锛屽鏈変镜鐘�锛岃珛(q菒ng)鑱�(li谩n)绯绘垜鍊戠珛鍗冲埅闄�锛屽彟锛氭湰鏂囧儏浠ｈ〃浣滆€呭€�(g猫)浜鸿榛�(di菐n)锛岃垏鏈恫(w菐ng)绔欑劇(w煤)闂�(gu膩n)銆傚叾鍘熷壍(chu脿ng)鎬т互鍙婃枃涓櫝杩版枃瀛楀拰鍏�(n猫i)瀹规湭缍�(j墨ng)鏈珯璀夊(sh铆)锛屽皪(du矛)鏈枃浠ュ強鍏朵腑鍏ㄩ儴鎴栬€呴儴鍒嗗収(n猫i)瀹广€佹枃瀛楃殑鐪熷(sh铆)鎬�銆佸畬鏁存€�銆佸強鏅�(sh铆)鎬ф湰绔欎笉浣滀换浣曚繚璀夋垨鎵胯锛岃珛(q菒ng)璁€鑰呭儏浣滃弮鑰�锛屽苟璜�(q菒ng)鑷鏍稿(sh铆)鐩搁棞(gu膩n)鍏�(n猫i)瀹�銆�
|
鏂囩珷鎼滅储
鎮ㄧ従(xi脿n)鍦ㄧ殑浣嶇疆锛� 
