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鍙嬫儏鎻愮ず锛氭湰绔欐彁渚涘叏鍦�(gu贸)400澶氭墍楂樼瓑闄㈡牎鎷涙敹纰╁＋銆佸崥澹爺绌剁敓鍏ュ(xu茅)鑰冭│姝峰勾鑰冪爺鐪熼銆佽€冨崥鐪熼銆佺瓟妗�锛岄儴鍒嗗(xu茅)鏍℃洿鏂拌嚦2012骞�锛�2013骞达紱鍧囨彁渚涙敹璨�(f猫i)涓嬭級銆� 涓嬭級娴佺▼锛� 鑰冪爺鐪熼 榛�(di菐n)鎿娾€�鑰冪爺瑭﹀嵎鈥濃€濅笅杓�; 鑰冨崥鐪熼 榛�(di菐n)鎿娾€�鑰冨崥瑭﹀嵎搴�(k霉)鈥� 涓嬭級
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839-绱�(x矛)鑳炵敓鐗╁(xu茅)
瑕佹眰鑰冪敓鍏ㄩ潰绯荤当(t菕ng)鍦扮悊瑙ｅ苟鎺屾彙绱�(x矛)鑳炵敓鐗╁(xu茅)鐨勫熀鏈蹇点€佸熀鏈悊璜栧拰鐮旂┒鏂规硶锛岃兘鐔熺反閬�(y霉n)鐢ㄧ窗(x矛)
鑳炵敓鐗╁(xu茅)鐭ヨ瓨(sh铆)鍒嗘瀽鐢熺墿瀛�(xu茅)鍩烘湰鍟忛锛屼簡瑙ｇ窗(x矛)鑳炵敓鐗╁(xu茅)鐨勬渶鏂伴€�(j矛n)灞�銆�
---灞辨澅澶у(xu茅)鑰冪爺澶х侗 涓€銆佺窗(x矛)鑳炵敓鐗╁(xu茅)鐧�(f膩)灞曟鍙�
1锛庝簡瑙ｇ窗(x矛)鑳炵殑鐧�(f膩)鐝�(xi脿n)锛岀窗(x矛)鑳炲(xu茅)瑾殑鍓�(chu脿ng)绔嬪強鍏跺収(n猫i)瀹硅榛�(di菐n)鍜屾剰缇�
2锛庝簡瑙ｇ窗(x矛)鑳炵敓鐗╁(xu茅)鍚勭櫦(f膩)灞曢殠娈电殑鐗归粸(di菐n)
3锛庝簡瑙ｇ窗(x矛)鑳炵敓鐗╁(xu茅)鐨勫舰鎴愬拰鐣�(d膩ng)鍓嶈垏浠婂悗鐨勭櫦(f膩)灞曟柟鍚�--鍒嗗瓙绱�(x矛)鑳炵敓鐗╁(xu茅)
浜屻€佺窗(x矛)鑳炵殑鍩烘湰绲�(ji茅)妲�(g貌u)鑸囧寲瀛�(xu茅)绲勬垚
1锛庣窗(x矛)鑳炵殑褰㈡厠(t脿i)绲�(ji茅)妲�(g貌u)
浜嗚В绱�(x矛)鑳炲舰鐙€銆佸ぇ灏忓拰绋鐨勫妯ｆ€�
鐞嗚В绱�(x矛)鑳炴槸鐢熷懡娲诲嫊(d貌ng)鐨勫熀鏈柈浣�
鎺屾彙鍕�(d貌ng)鐗╃窗(x矛)鑳炵殑涓€鑸祼(ji茅)妲�(g貌u)妯″紡
鎺屾彙妞嶇墿绱�(x矛)鑳炶垏鍕�(d貌ng)鐗╃窗(x矛)鑳�銆佸師鏍哥窗(x矛)鑳炶垏鐪熸牳绱�(x矛)鑳炵殑涓昏绲�(ji茅)妲�(g貌u)宸垾
2锛庣窗(x矛)鑳炵殑鍖栧(xu茅)绲勬垚鍙婂叾鎰忕京
浜嗚В鍏冪礌锛氫富瑕佸厓绱犮€佸畯閲�銆佸井閲忓拰鐥曢噺鍏冪礌
浜嗚В姘淬€佺劇(w煤)姗�(j墨)楣藉拰闆㈠瓙
鎺屾彙鏈夋(j墨)灏忓垎瀛愶細灏忓垎瀛愮硸椤�銆佹皑鍩洪吀銆佹牳鑻烽吀銆佽剛璩�(zh矛)
鎺屾彙鐢熺墿澶у垎瀛愶細鏍搁吀銆佽泲鐧借唱(zh矛)銆佽剛椤�銆佸绯�
3锛庢帉鎻＄窗(x矛)鑳炵殑鍏辨€�锛岀窗(x矛)鑳炲舰鎱�(t脿i)绲�(ji茅)妲�(g貌u)鍜屽寲瀛�(xu茅)绲勬垚鑸囧姛鑳界殑鐩搁棞(gu膩n)鎬�
4锛庝簡瑙ｇ梾姣掕垏绱�(x矛)鑳炵殑闂�(gu膩n)绯�
涓夈€佺窗(x矛)鑳炲櫒鐨勭祼(ji茅)妲�(g貌u)鑸囧姛鑳�
1锛庡収(n猫i)鑶滅郴绲�(t菕ng)鐨勬蹇靛強鍏剁祫鎴愭垚鍝�
2锛庡収(n猫i)璩�(zh矛)缍�(w菐ng)
1锛夋帉鎻″収(n猫i)璩�(zh矛)缍�(w菐ng)鐨勫舰鎱�(t脿i)绲�(ji茅)妲�(g貌u)鐗瑰緛鍜岄鍒ワ紙绮楅潰鍏�(n猫i)璩�(zh矛)缍�(w菐ng)鍜屽厜闈㈠収(n猫i)璩�(zh矛)缍�(w菐ng)锛�
2锛夌悊瑙ｆ帉鎻＄矖闈㈠収(n猫i)璩�(zh矛)缍�(w菐ng)鐨勪富瑕佸姛鑳�
鎺屾彙鎸変俊铏�(h脿o)鍋囪鍙冭垏鍒嗘硨铔嬬櫧鍜屾憾閰堕珨閰剁瓑铔嬬櫧鍚堟垚
鎺屾彙铔嬬櫧璩�(zh矛)鐨勪慨椋�(鍖呮嫭 N-閫ｆ帴绯栧熀鍖�銆侀叞鍩哄寲绛�)鍜屾纰烘姌鐤�
3锛夋帉鎻″厜闈㈠収(n猫i)璩�(zh矛)缍�(w菐ng)鐨勫姛鑳斤細鑶滆剛椤炲拰鐢鹃婵€绱犲悎鎴�銆佽В姣掑拰鍙冭垏绯栧厓鍚堟垚鑸囧垎瑙ｇ瓑
3锛庨珮鐖惧熀楂�
1锛夋帉鎻￠珮鐖惧熀楂旂殑褰㈡厠(t脿i)绲�(ji茅)妲�(g貌u)鐗归粸(di菐n)銆佺祼(ji茅)妲�(g貌u)鍒嗗崁(q奴)鍙婂悇鍗€(q奴)鐨勬(bi膩o)蹇楁€ч叾
2
2锛夋帉鎻￠珮鐖惧熀楂旂殑鍔熻兘
铔嬬櫧璩�(zh矛)鐨勪慨椋惧拰鍔犲伐锛歂-閫ｆ帴绯栧熀鍖�銆丱-閫ｆ帴绯栧熀鍖栬垏纾烽吀鍖栧拰纭吀鍖�
4锛庢憾閰堕珨
1锛夋帉鎻℃憾閰堕珨鐨勫舰鎱�(t脿i)绲�(ji茅)妲�(g貌u)鍙婂寲瀛�(xu茅)绲勬垚鐗归粸(di菐n)
2锛夋帉鎻℃憾閰堕珨鐨勪簽椤炲妰鍒嗗拰鍔熻兘
婧堕叾楂旂殑鍩烘湰鍔熻兘锛嶆秷鍖栦綔鐢�
婧堕叾楂旂殑鍏朵粬鍔熻兘(鍕�(d貌ng)鐗╁彈绮鹃亷绋嬩腑鍜屽厤鐤弽鎳�(y墨ng)涓殑浣滅敤绛�)
3锛変簡瑙ｆ憾閰堕珨鐨勭櫦(f膩)鐢�
5锛庡井楂�
1锛夋帉鎻″井楂旂殑鍏╃ó椤炲瀷鍙婂叾鍏卞悓鐨勫舰鎱�(t脿i)绲�(ji茅)妲�(g貌u)鍜岄叾鐗瑰緛
2锛夋帉鎻℃憾閰堕珨鍜屽井楂旂殑鍗€(q奴)鍒�
3锛夌悊瑙ｉ亷姘у寲鐗╅叾楂旂殑閰剁壒榛�(di菐n)鍜屽姛鑳斤紞瑙ｆ瘨浣滅敤锛屾鐗╁厜鍛煎惛涓殑涔欓唶閰镐唬璎�
4锛変簡瑙ｄ箼閱涢吀寰挵(hu谩n)楂旂殑閰剁壒榛�(di菐n)鍜屽姛鑳斤紞鍙冭垏绋瓙钀岀櫦(f膩)涓殑绯栫暟鐢熶綔鐢�
5锛変簡瑙ｉ棞(gu膩n)浜庡井楂旂殑鐧�(f膩)鐢熷晱椤�
6锛庣窔绮掗珨
1锛夋帉鎻＄窔绮掗珨椤井褰㈡厠(t脿i)鐗瑰緛鍜屼富瑕佸姛鑳芥瑕�
2锛夋帉鎻＄窔绮掗珨瓒呭井绲�(ji茅)妲�(g貌u)鑸囧姛鑳藉畾浣嶅強鍚勯儴鍒嗙殑绲�(ji茅)妲�(g貌u)鍜屽寲瀛�(xu茅)绲勬垚鐗归粸(di菐n)
3锛夋帉鎻″収(n猫i)鑶滈€�(j矛n)琛岃兘閲忚綁(zhu菐n)鍖�(姘у寲纾烽吀鍖�)鐨勫垎瀛愬拰瓒呭垎瀛愮祼(ji茅)妲�(g貌u)鍩虹(ch菙)鑸囪綁(zhu菐n)鍖栨(j墨)鍒�
7锛庤憠缍犻珨
1锛夋帉鎻¤憠缍犻珨鐨勯’寰舰鎱�(t脿i)鐗瑰緛鍜岃秴寰祼(ji茅)妲�(g貌u)
2锛夋帉鎻¤憠缍犻珨鐨勪富瑕佸姛鑳斤紞鍏夊悎浣滅敤
3锛夌悊瑙ｉ鍥婇珨鑶滈€�(j矛n)琛屽厜鍙嶆噳(y墨ng)(鍏夊悎纾烽吀鍖�)鐨勫垎瀛愬拰瓒呭垎瀛愮祼(ji茅)妲�(g貌u)鍩虹(ch菙)鍜屽弽鎳�(y墨ng)閬庣▼
8锛庣窔绮掗珨鍜岃憠缍犻珨鐨勫崐鑷富鎬�
1锛夋帉鎻″崐鑷富鎬х殑涓昏琛ㄧ従(xi脿n)
2锛夌悊瑙ｇ窗(x矛)鑳炶唱(zh矛)鍚堟垚鐨勭窔绮掗珨钁夌稜楂旇泲鐧戒箣杞�(zhu菐n)閬�(y霉n)姗�(j墨)鍒�
3锛変簡瑙ｇ窔绮掗珨鍜岃憠缍犻珨鐨勭箒娈栨柟寮�
4锛変簡瑙ｇ窔绮掗珨鍜岃憠缍犻珨鐨勮捣婧愶細鍏�(n猫i)鍏辩敓璧锋簮瀛�(xu茅)瑾垏闈炲収(n猫i)鍏辩敓璧锋簮瀛�(xu茅)瑾�
9锛庝簡瑙ｅ唬缇╁拰鐙圭京鐨勭窗(x矛)鑳為鏋舵蹇�
10锛庡井绠�
1锛夋帉鎻″井绠＄殑褰㈡厠(t脿i)绲�(ji茅)妲�(g貌u)鍜屽井绠＄殑绋鍙婂垎甯�
2锛夋帉鎻″井绠¤泲鐧藉拰寰绲�(ji茅)鍚堣泲鐧�
3锛夋帉鎻″井绠＄殑绲勮銆佸幓绲勮鑸囧井绠＄祫绻斾腑蹇�锛屽井绠＄殑鈥滆笍杌娾€濈従(xi脿n)璞�锛屾案涔呮€у井绠″拰鏆檪(sh铆)鎬у井绠�
4锛夌悊瑙ｅ井绠＄殑鍔熻兘
5锛夋帉鎻″井绠＄殑鐗圭暟鎬ц棩鐗╁拰寰绲勬垚鐨勭窗(x矛)鑳炲櫒
11锛庡井绲�
3
1锛夋帉鎻″井绲茬殑褰㈡厠(t脿i)绲�(ji茅)妲�(g貌u)鍙婃(g貌u)鎴愬井绲茬殑鍒嗗瓙--鑲屽嫊(d貌ng)铔嬬櫧
2锛夋帉鎻″井绲茬殑绲勮鍜岃В鑱�銆佹案涔呮€у井绲茶垏鏆檪(sh铆)鎬у井绲�
3锛夋帉鎻″井绲茬祼(ji茅)鍚堣泲鐧�
4锛夌悊瑙ｆ┇绱嬭倢绾栫董(绱�(x矛)鑳�)涓殑寰挡绯荤当(t菕ng)鑸囪倢鑲夋敹绺(j墨)鍒�
5锛夋帉鎻￠潪鑲岃倝绱�(x矛)鑳炰腑寰挡鐨勭壒榛�(di菐n)鍜屽姛鑳斤細寰胆姣涗腑鐨勬敮鏋朵綔鐢ㄣ€佽優璩�(zh矛)娴佸嫊(d貌ng)鍜岀窗(x矛)鑳炵Щ鍕�(d貌ng)涓殑浣�
鐢�銆佽優璩�(zh矛)鍒嗚涓殑鏀剁府鐠�(hu谩n)浣滅敤銆佺窗(x矛)鑳為€ｆ帴涓殑浣滅敤
6锛夋帉鎻″井绲茬殑鐗圭暟鎬х牬澹炶棩鐗╁拰绌�(w臎n)瀹氳棩鐗�
12锛庝腑闁撶簴缍�
1锛夋帉鎻′腑闁撶簴缍殑涓€鑸舰鎱�(t脿i)鍜岄鍨嬪強椤炲瀷鐨勭窗(x矛)鑳炵壒鐣版€�
2锛夌悊瑙ｄ腑闁撶簴缍泲鐧藉垎瀛愮殑涓€鑸祼(ji茅)妲�(g貌u)妯″紡鍙婁腑闁撶簴缍殑绲勮
3锛変簡瑙ｄ腑闁撶簴缍祼(ji茅)鍚堣泲鐧�
4锛夌悊瑙ｄ腑闁撶簴缍殑鍔熻兘锛氭敮鏋跺拰閫ｆ帴浣滅敤锛涗俊铏�(h脿o)鍌抽仦鍜屽熀鍥犺〃閬�(d谩)绛夋柟闈㈢殑鍙兘浣滅敤銆�
13锛庢牳绯栭珨
1锛夋帉鎻℃牳绯栭珨鐨勫舰鎱�(t脿i)绲�(ji茅)妲�(g貌u)鍜岄鍒�
2锛変簡瑙ｆ牳绯栭珨妲�(g貌u)鎴愬垎瀛愬強瑙ｉ洟鍜岄噸绲勮绛夌爺绌剁祼(ji茅)鏋�
3锛夋帉鎻℃牳绯栭珨鐨勫姛鑳介儴浣嶅強鍏跺湪铔嬬櫧璩�(zh矛)鍚堟垚涓殑浣滅敤锛歮RNA 绲�(ji茅)鍚堥儴浣�銆丳 浣嶃€丄 浣�銆佽偨閰�
鍩鸿綁(zhu菐n)绉婚叾閮ㄤ綅銆丟 鍥犲瓙閮ㄤ綅銆丒 浣嶄簡瑙ｄ綔鐢ㄤ簬鏍哥硸楂旂殑铔嬬櫧璩�(zh矛)鍚堟垚鐨勬姂鍒跺姂鐞嗚В澶氳仛鏍哥硸楂斿湪铔嬬櫧鍚�
鎴愪腑鐨勬剰缇╁拰鏍哥硸楂斿惊鐠�(hu谩n)
4锛夋帉鎻＄窗(x矛)鑳炶唱(zh矛)鍩鸿唱(zh矛)閫斿緫鍜屽収(n猫i)璩�(zh矛)缍�(w菐ng)閫斿緫鍚堟垚鐨勮泲鐧借唱(zh矛)鐨勫懡閬�(y霉n)鍜岃綁(zhu菐n)閬�(y霉n)姗�(j墨)鍒�
鍥�銆佺窗(x矛)鑳炲熀璩�(zh矛)鑸囧姛鑳�
1锛庣窗(x矛)鑳炲鍩鸿唱(zh矛)
鎺屾彙姒傚康鍜屽姛鑳芥剰缇�
1锛夌悊瑙ｆ帉鎻″嫊(d貌ng)鐗╃窗(x矛)鑳炵殑鑳炲鍩鸿唱(zh矛)
1.1锛夎啝鍘熺簴缍細椤炲瀷鍙婂垎瀛愮祼(ji茅)妲�(g貌u)鍜岀簴缍壒寰�锛涘悎鎴�銆佷慨椋�銆佺祫瑁濆拰浜よ伅(li谩n)锛涘姛鑳�
1.2锛夊綀鎬э紙褰堝姏锛夎泲鐧界簴缍細绲�(ji茅)妲�(g貌u)鐗归粸(di菐n)銆佸垎甯冨拰鍔熻兘
1.3锛夋皑鍩鸿仛绯栵細鍒嗗瓙绲�(ji茅)妲�(g貌u)鐗归粸(di菐n)銆佺ó椤�銆佺壒鎬у拰鍔熻兘鎰忕京锛涢€忔槑璩�(zh矛)閰哥殑鐗规畩鍔熻兘鎰忕京
1.4锛夎泲鐧借仛绯栵細鍒嗗瓙绲�(ji茅)妲�(g貌u)鐗归粸(di菐n)锛涜垏閫忔槑璩�(zh矛)閰哥偤杌哥殑鏇村ぇ寰�(f霉)鍚堢祼(ji茅)妲�(g貌u)锛涘姛鑳芥剰缇╋紙鍖呮嫭鍙冭垏妲�(g貌u)鎴�
鍩哄簳鑶滐級
1.5锛夊堡绮橀€ｈ泲鐧藉拰绾栫矘閫ｈ泲鐧斤細绲�(ji茅)妲�(g貌u)鐗归粸(di菐n)銆佸姛鑳芥剰缇�
1.6锛夎優闁撶矘閫ｅ垎瀛愶細渚濊炒浜� Ca2+鐨勶紝涓嶄緷璩翠簬 Ca2+鐨�锛涘姛鑳芥剰缇�
1.7锛変簡瑙ｆ鐗╃窗(x矛)鑳炵窗(x矛)鑳炲锛氭垚鍒嗐€佺祼(ji茅)妲�(g貌u)鍜屽姛鑳芥娉�
2锛夌窗(x矛)鑳炶唱(zh矛)鍩鸿唱(zh矛)鐨勬蹇靛拰鍔熻兘
2.1锛変簡瑙ｉ棞(gu膩n)浜庣窗(x矛)鑳炶唱(zh矛)鍩鸿唱(zh矛)鐨勪笉鍚屾蹇靛拰绲�(ji茅)妲�(g貌u)鍟忛
2.2锛夌悊瑙ｇ窗(x矛)鑳炶唱(zh矛)鍩鸿唱(zh矛)鐨勫姛鑳�
4
浜�銆佺窗(x矛)鑳炴牳鑸囨煋鑹查珨
1锛庢牳琚啘锛堟牳鑶滐級
1锛夋帉鎻℃牳琚啘鐨勪竴鑸舰鎱�(t脿i)绲�(ji茅)妲�(g貌u)鐗归粸(di菐n)鍜岀敓鐗╁(xu茅)鎰忕京
2锛夋帉鎻℃牳瀛斿京(f霉)鍚堥珨鐨勭祼(ji茅)妲�(g貌u)鍜屽姛鑳�
绲�(ji茅)妲�(g貌u)锛氭牳绫冩ā鍨�
鍔熻兘锛氭牳铔嬬櫧鐨勮几鍏�銆丷NA 鍜屾牳绯栭珨浜炲柈浣嶇殑杓稿嚭
3锛夋帉鎻℃牳绾栧堡锛堟牳鑶滈鏋讹級鐨勫舰鎱�(t脿i)绲�(ji茅)妲�(g貌u)鐗归粸(di菐n)銆佹€ц唱(zh矛)锛堜腑闁撶簴缍鏃忥級鍜屽姛鑳芥剰缇�
2锛庢煋鑹茶唱(zh矛)
1锛夋帉鎻℃煋鑹茶唱(zh矛)鐨勭稉(j墨ng)鍏告蹇靛拰鐝�(xi脿n)浠ｆ蹇�
2锛夋帉鎻＄祫铔嬬櫧鐨勭ó椤炲拰鐗归粸(di菐n)
3锛夋帉鎻℃煋鑹茶唱(zh矛)鐨勫熀鏈祼(ji茅)妲�(g貌u)锛嶅康鐝犳ā鍨嬪拰绲�(ji茅)妲�(g貌u)鐨勫熀鏈柈浣嶏紞鏍稿皬楂�
4锛夋帉鎻℃煋鑹茶唱(zh矛)鐨勯鍨嬪拰鍚勯鏌撹壊璩�(zh矛)鐨勫畾缇�
5锛変簡瑙ｆ煋鑹茶唱(zh矛)鐨勯潪绲勮泲鐧斤細鎬ц唱(zh矛)锛屼竴鑸祼(ji茅)妲�(g貌u)妯″紡銆佸姛鑳芥剰缇�
3锛庢牳浠�
1锛夋帉鎻￠’寰按骞崇殑鏍镐粊褰㈡厠(t脿i)鍜岀窗(x矛)鑳炲寲瀛�(xu茅)鐗瑰緛
2锛夋帉鎻℃牳浠佺殑瓒呭井绲�(ji茅)妲�(g貌u)鍒嗛儴鍜屽悇閮ㄥ垎鐨勭祼(ji茅)妲�(g貌u)绲勬垚鐗归粸(di菐n)
3锛夌悊瑙ｆ帉鎻℃牳浠佺殑鍔熻兘锛歳RNA 鐨勫悎鎴愬拰鏍哥硸楂斾簽鍠綅鐨勭祫瑁�
4锛庢煋鑹查珨
1锛夋帉鎻℃煋鑹查珨鍖呰(绲�(ji茅)妲�(g貌u)鎴栬秴鍒嗗瓙绲�(ji茅)妲�(g貌u))鐨勫叐绋富瑕佹ā鍨�
2锛夋帉鎻′腑鏈熸煋鑹查珨鐨勯’寰舰鎱�(t脿i)瀛�(xu茅)
3锛夋帉鎻℃煋鑹查珨 DNA 搴忓垪鐨勯噸寰�(f霉)鎬�銆佸垎椤炲拰鍚勯 DNA 搴忓垪鐨勬帓鍒楀垎甯�
4锛夋帉鎻′繚璀夋煋鑹查珨涓栦唬绌�(w臎n)瀹氱殑绲�(ji茅)妲�(g貌u)閮ㄤ綅鍜岄棞(gu膩n)閸靛簭鍒楀強鍏剁祼(ji茅)妲�(g貌u)钁楃挡绮�-钁楃挡榛�(di菐n)銆佺绮�銆佽嚜涓诲京(f霉)鍒�
搴忓垪
5锛変簡瑙ｅ法澶ф煋鑹查珨锛氬绶氭煋鑹查珨鍜岀噲鍒锋煋鑹查珨
5锛庢牳楠ㄦ灦鍜屾牳鍩鸿唱(zh矛)
1锛夌悊瑙ｆ牳楠ㄦ灦鐨勬蹇碉細寤ｇ京鐨勬牳楠ㄦ灦鍜岀嫻缇╃殑鏍搁鏋�銆�
2锛夋帉鎻℃牳鍩鸿唱(zh矛)锛堢嫻缇╂牳楠ㄦ灦锛夌殑涓€鑸舰鎱�(t脿i)绲�(ji茅)妲�(g貌u)鍜屽寲瀛�(xu茅)绲勬垚鐗归粸(di菐n)浠ュ強鍔熻兘鎰忕京
3锛変簡瑙ｆ煋鑹查珨鏀灦鍙婂叾鑸囨牳鍩鸿唱(zh矛)鐨勯棞(gu膩n)绯�
6锛庣悊瑙ｆ帉鎻＄窗(x矛)鑳炴牳鐨勫姛鑳�
鍏�銆佺窗(x矛)鑳炶啘鑸囩窗(x矛)鑳炶〃闈㈢殑绲�(ji茅)妲�(g貌u)鑸囪瓨(sh铆)鍒�
1锛庤唱(zh矛)鑶滅殑鍖栧(xu茅)绲勬垚鍜岀祼(ji茅)妲�(g貌u)
1锛夋帉鎻℃(g貌u)鎴愯唱(zh矛)鑶滅殑涓昏鍒嗗瓙椤炲垾鍙婂叾鐗归粸(di菐n)鍜屾剰缇�
1.1锛夎剛璩�(zh矛)锛氱７鑴�銆佺硸鑴�銆佽喗鍥洪唶銆傞檮锛氫汉宸ヨ剛璩�(zh矛)楂斿強鍏舵噳(y墨ng)鐢�
5
1.2锛夎泲鐧借唱(zh矛)锛氬鍦ㄨ泲鐧姐€佸収(n猫i)鍦ㄨ泲鐧�銆佽剛閷ㄥ畾铔嬬櫧锛涜法鑶滆泲鐧界殑涓€鑸祼(ji茅)妲�(g貌u)鐗归粸(di菐n)锛涜啘铔嬬櫧鐨勭敓鐗�
瀛�(xu茅)鍔熻兘
1.3锛夌硸椤�銆傞檮锛欰BO 琛€鍨嬫姉鍘�
2锛夋帉鎻¤唱(zh矛)鑶滅殑绲�(ji茅)妲�(g貌u)妯″瀷
2.1锛変簡瑙ｆ鍙蹭笂鐨勪笁鍊�(g猫)涓昏妯″瀷锛欸orter 鍜� Grendel 鐨勮剛闆欏堡妯″瀷锛汥anielli-Davson 妯″瀷锛堜笁
鏄庢不妯″瀷锛�锛汻obertson 妯″瀷锛堝柈浣嶈啘妯″瀷锛�
2.2锛夌悊瑙ｆ帉鎻＄従(xi脿n)浠ｈ寤ｆ硾鎺ュ彈鐨勬祦鍕�(d貌ng)閼插祵妯″瀷锛氬熀鏈榛�(di菐n)锛岀爺绌舵柟娉曘€�
2.3锛変簡瑙ｈ唱(zh矛)鑶滅祼(ji茅)妲�(g貌u)鐮旂┒鐨勫(sh铆)渚�--鍝轰钩椤炵磪琛€鐞冪殑璩�(zh矛)鑶滐細鏂规硶锛岀祼(ji茅)鏋�銆傝唱(zh矛)鑶滈鏋跺強鍏跺瓨鍦ㄧ殑鏅�
閬嶆€у晱椤屻€�
2锛庤唱(zh矛)鑶滅殑鍔熻兘
1锛夌悊瑙ｆ帉鎻＄墿璩�(zh矛)鐨勮法鑶滈亱(y霉n)杓�
1.1锛夊ぇ鍒嗗瓙鎴栭绮掔殑璺ㄨ啘閬�(y霉n)杓革細鍚炲櫖銆佽優椋诧紙鍙楅珨浠嬪皫(d菐o)鐨勫収(n猫i)鍚烇級銆佽優鍚�銆佺┛鑳為亱(y霉n)杓�
1.2锛夐洟瀛愬拰灏忓垎瀛愮殑璺ㄨ啘閬�(y霉n)杓�
琚嫊(d貌ng)閬�(y霉n)杓革細鐗归粸(di菐n)锛涚啊(ji菐n)鍠摯(ku貌)鏁�锛屽崝(xi茅)鍔╂摯(ku貌)鏁�锛涜級楂�銆佽綁(zhu菐n)閬�(y霉n)铔嬬櫧鐨勬蹇�
涓诲嫊(d貌ng)閬�(y霉n)杓革細鐗归粸(di菐n)锛涘垵绱�(j铆)涓诲嫊(d貌ng)閬�(y霉n)杓�锛涙绱�(j铆)涓诲嫊(d貌ng)閬�(y霉n)杓�
2锛夋帉鎻¤唱(zh矛)鑶滅殑鍏朵粬鍔熻兘
3锛夌窗(x矛)鑳炶〃闈㈢殑鐗瑰寲绲�(ji茅)妲�(g貌u)
3.1锛変簡瑙ｇ窗(x矛)鑿岀窗(x矛)鑳炵殑闉瘺锛氱祼(ji茅)妲�(g貌u)鍜岄亱(y霉n)鍕�(d貌ng)姗�(j墨)鍒�
3.2锛変簡瑙ｅ叾浠栫壒鍖栫祼(ji茅)妲�(g貌u)锛嶉灜姣涖€佺簴姣�銆佸井绲ㄦ瘺銆佺挡瓒炽€佺墖瓒崇瓑
4锛夌窗(x矛)鑳炵殑閫ｆ帴
4.1锛夋帉鎻″皝闁夐€ｆ帴锛氶€ｆ帴鐗归粸(di菐n)鍙婄敓鐗╁(xu茅)鎰忕京
4.2锛夋帉鎻￠尐瀹氶€ｆ帴鍙婂叾鐢熺墿瀛�(xu茅)鎰忕京
4.2.1锛夋帉鎻℃⿱绮掗€ｆ帴鍜屽崐姗嬬矑閫ｆ帴
4.2.2锛夋帉鎻＄矘钁楅€ｆ帴锛堢矘钁楀付鍜岀矘钁楁枒锛�
4.3锛夋帉鎻￠€氳▕閫ｆ帴
4.3.1锛夋帉鎻￠枔闅欓€ｆ帴绲�(ji茅)妲�(g貌u)鐗归粸(di菐n)鍜屽姛鑳戒互鍙婇€ｆ帴瀛愭蹇�
4.3.2锛夋帉鎻″寲瀛�(xu茅)绐佽Ц
4.3.2锛変簡瑙ｆ鐗╃窗(x矛)鑳炵殑鑳為枔閫ｇ挡
4.4锛変簡瑙ｇ窗(x矛)鑳為檮钁�(绱�(x矛)鑳炵矘闄�)锛氭蹇�锛涜垏绱�(x矛)鑳為€ｆ帴鐨勯棞(gu膩n)绯诲拰鐢熺墿瀛�(xu茅)鎰忕京
涓�銆佺窗(x矛)鑳為€氳▕鍜屼俊铏�(h脿o)杞�(zhu菐n)灏�(d菐o)
1锛庣悊瑙ｅ苟鎺屾彙绱�(x矛)鑳炶瓨(sh铆)鍒ュ拰绱�(x矛)鑳為€氳▕鏈夐棞(gu膩n)鐨勫咕鍊�(g猫)姒傚康锛氱窗(x矛)鑳炶瓨(sh铆)鍒�銆佺窗(x矛)鑳為€氳▕銆佸彈楂�銆佷俊铏�(h脿o)閫氳矾銆�
绗竴淇′娇銆佺浜屼俊浣�
2锛庢帉鎻¤優鍏�(n猫i)鍙楅珨浠嬪皫(d菐o)鐨勪俊铏�(h脿o)閫氳矾鍙婁俊铏�(h脿o)鍒嗗瓙
3锛庢帉鎻¤啘鍙楅珨浠嬪皫(d菐o)鐨勪俊铏�(h脿o)閫氳矾锛�
6
鑸囷姬铔嬬櫧鍋惰伅(li谩n)鐨勶細cAMP 閫氳矾鍙婁俊铏�(h脿o)鍒嗗瓙銆佽倢閱囩７鑴傞€氳矾鍙婁俊铏�(h脿o)鍒嗗瓙
閰堕棞(gu膩n)鑱�(li谩n)鍙楅珨淇¤櫉(h脿o)閫氳矾
闆㈠瓙閫氶亾闂�(gu膩n)鑱�(li谩n)鍙楅珨
鍏�銆佺窗(x矛)鑳炲娈栧強鍏惰(di脿o)鎺�
1锛庝簡瑙ｇ窗(x矛)鑳炵箒娈�銆佺窗(x矛)鑳炲垎瑁傚拰绱�(x矛)鑳炲懆鏈熼枔鐨勯棞(gu膩n)绯诲強绱�(x矛)鑳炲垎瑁傛柟寮�
2锛庣窗(x矛)鑳炴湁绲插垎瑁�
1锛夌悊瑙ｆ湁绲插垎瑁傜殑褰㈡厠(t脿i)瀛�(xu茅)閬庣▼锛屾檪(sh铆)鐩稿妰鍒嗗強鍚勬檪(sh铆)鐩哥殑璁婂寲妯�(bi膩o)蹇�
2锛夋帉鎻℃棭涓湡鏌撹壊楂旂殑绉诲嫊(d貌ng)鑸囩础閷橀珨鐨勫舰鎴愬拰绲�(ji茅)妲�(g貌u)
3锛夋帉鎻″濡硅憲绲茬矑鐨勫垎闆㈣垏鍚庢湡鏌撹壊楂旂殑绉诲嫊(d貌ng)
4锛夋帉鎻¤優璩�(zh矛)鍒嗚
5锛変簡瑙ｆ鐗╃窗(x矛)鑳炴湁绲插垎瑁傜殑鐗归粸(di菐n)鑸囨煇浜涚敓鐗╃壒娈婂舰寮忕殑鏈夌挡鍒嗚锛堜腑銆佸悗鏈熻綁(zhu菐n)鍖栧拰濮愬鏌撹壊
楂斿垎闆㈢殑姗�(j墨)鍒讹級
3锛庢笡鏁�(sh霉)鍒嗚
1锛夋帉鎻℃笡鏁�(sh霉)鍒嗚鐨勫舰鎱�(t脿i)瀛�(xu茅)閬庣▼锛屾檪(sh铆)鏈熷妰鍒嗗拰鍚勬湡鐨勪富瑕佽畩鍖栫壒寰�
2锛夋帉鎻￠噸瑕佷簨浠跺拰閲嶈绲�(ji茅)妲�(g貌u)鍒嗘瀽锛�
鍚屾簮鏌撹壊楂旂殑閰嶅皪(du矛)鑸囪伅(li谩n)鏈�(hu矛)寰�(f霉)鍚堥珨鍜� Z-DNA
鍚屾簮鏌撹壊楂旈枔鐨勪氦鎻�銆佷氦鎻涙(j墨)鍒跺拰 P-DNA
3锛夌悊瑙ｅ嵉姣嶇窗(x矛)鑳炵殑娓涙暩(sh霉)鍒嗚鐗归粸(di菐n)
4锛庣窗(x矛)鑳炲懆鏈熷強绱�(x矛)鑳炲懆鏈熷拰绱�(x矛)鑳炲娈栫殑瑾�(di脿o)鎺�
1锛夋帉鎻″懆鏈熷収(n猫i)绱�(x矛)鑳�銆佸懆鏈熷绱�(x矛)鑳�(浼戞绱�(x矛)鑳�)銆佺窗(x矛)鑳炲懆鏈熸椹�(y脿n)榛�(di菐n)銆丟o 鏈熺窗(x矛)鑳炵瓑姒傚康
2锛変簡瑙ｇ窗(x矛)鑳炲懆鏈熺殑鏅�(sh铆)鐩稿妰鍒�锛屾檪(sh铆)绋嬭畩鐣板強鐮旂┒绱�(x矛)鑳炲懆鏈熺殑鏈€鍩烘湰鏂规硶锛嶇窗(x矛)鑳炲悓姝ュ寲鏂规硶鍜屽懆
鏈熸檪(sh铆)闁撴脯(c猫)瀹氭硶
3锛夌悊瑙ｃ€佹帉鎻＄窗(x矛)鑳炲懆鏈熷拰绱�(x矛)鑳炲娈栫殑瑾�(di脿o)鎺�
4锛夌悊瑙ｈ(di脿o)鎺х窗(x矛)鑳炲娈栧拰绱�(x矛)鑳炲懆鏈熺殑鍏朵粬涓昏鍥犵礌
涔�銆佺窗(x矛)鑳炲垎鍖栥€佸噵浜�銆佽“鑰佽垏鐧岃畩
1锛庣窗(x矛)鑳炵殑鍒嗗寲
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鏂囩珷鎼滅储
鎮ㄧ従(xi脿n)鍦ㄧ殑浣嶇疆锛� 
