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鍙嬫儏鎻愮ず锛氭湰绔欐彁渚涘叏鍦�400澶氭墍楂樼瓑闄㈡牎鎷涙敹纰╁＋銆佸崥澹爺绌剁敓鍏ュ(xu茅)鑰冭│姝峰勾鑰冪爺鐪熼銆佽€冨崥鐪熼銆佺瓟妗�锛岄儴鍒嗗(xu茅)鏍℃洿鏂拌嚦2012骞�锛�2013骞�锛涘潎鎻愪緵鏀惰不涓嬭級銆� 涓嬭級娴佺▼锛� 鑰冪爺鐪熼 榛炴搳鈥�鑰冪爺瑭﹀嵎鈥濃€濅笅杓�; 鑰冨崥鐪熼 榛炴搳鈥�鑰冨崥瑭﹀嵎搴�鈥� 涓嬭級
625 鐢熺墿鍖栧(xu茅)(A)
1. 鑰冭│鍏�(n猫i)瀹�
鍩烘湰鐢熷寲鍒嗗瓙锛岀敓鐗╁寲瀛�(xu茅)涓殑鍖栧(xu茅)??锛涘寲瀛�(xu茅)姒傚康鑸囩敓鍖�锛涜泲鐧借唱(zh矛)绲�(ji茅)妲�(g貌u)鑸囧姛鑳斤細
姘ㄥ熀閰革紝鑲介嵉褰㈡垚涓€绱氱祼(ji茅)妲�(g貌u)锛屼簩绱氱祼(ji茅)妲�(g貌u)锛堣灪鏃嬨€佹姌鐤婂拰杞�(zhu菐n)瑙掞級锛屼笁绱氱祼(ji茅)妲�(g貌u)锛堢枏姘�
浣滅敤锛�锛屽洓绱氱祼(ji茅)妲�(g貌u)锛堜簽鍩虹祫瑁濓級锛屼竴绱氱祼(ji茅)妲�(g貌u)姹哄畾涓夌礆绲�(ji茅)妲�(g貌u)锛涜泲鐧借唱(zh矛)鐮旂┒鏂规硶鑸囨妧
琛�(sh霉)锛氳泲鐧借唱(zh矛)绱斿寲锛岃泲鐧借唱(zh矛)搴忓垪鍒嗘瀽锛岃泲鐧借唱(zh矛)鐨勫厤鐤(xu茅)鐮旂┒锛孨MR 鍜� X-ray 娉曠爺
绌惰泲鐧借唱(zh矛)鐨勭祼(ji茅)妲�(g貌u)锛汥NA銆丷NA 鑸囦俊鎭偝閬烇細鏍歌嫹閰�锛孌NA 闆欒灪鏃�锛孌NA 寰�(f霉)鍒�锛�
鍩哄洜琛ㄩ仈(d谩)鑸� mRNA锛屽瘑纰煎瓙锛岀湡鏍哥敓鐗╁収(n猫i)鍚瓙锛涘熀鍥犵爺绌舵柟娉曪細鏍搁吀鐮旂┒鎶€琛�(sh霉)锛�
DNA 閲嶇祫鎶€琛�(sh霉)锛屽叏鍩哄洜绲勫簭鍒楄垏鍒嗘瀽锛岀湡鏍哥敓鐗╁熀鍥犺〃閬�(d谩)瀹氶噺鑸囨搷浣滄妧琛�(sh霉)锛涚敓
鐗╅€�(j矛n)鍖栫爺绌讹細鍚屾簮鎬ц垏搴忓垪姣斿皪锛屽簭鍒楀悓婧愩€佺祼(ji茅)妲�(g貌u)鍚屾簮锛岄€�(j矛n)鍖栨ü锛岀爺绌剁敓鐗╅€�(j矛n)鍖�
鐨勭従(xi脿n)浠ｆ柟娉�锛涜绱呰泲鐧界祼(ji茅)妲�(g貌u)鑸囧姛鑳斤細琛€绱呰泲鐧借垏鑲岀磪铔嬬櫧锛屾哀绲�(ji茅)鍚堢殑鍗�(xi茅)鍚屾€�锛屾尝
鐖炬晥鎳�(y墨ng)锛岃钵琛€鐧�锛涢叾鐨勬蹇佃垏鍕曞姏瀛�(xu茅)锛氶叾淇冨弽鎳�(y墨ng)鐨勯珮鏁堟€ц垏鐗圭暟鎬�锛岄叾淇冨弽鎳�(y墨ng)鐨�
鐔卞姏瀛�(xu茅)锛岄叾淇冨弽鎳�(y墨ng)褰㈡垚閬庢浮鎱�(t脿i)锛岀背姘忔柟绋嬶紙鍙冩暩(sh霉)鎰忕京鑸囨柟绋嬫帹灏�(d菐o)锛夛紝閰剁殑鎶戝埗鍔�锛�
缍敓绱犺垏杓旈叾锛涘偓鍖栭鍨嬶細铔嬬櫧閰剁殑鍌寲姗熷埗锛岄噾灞洟瀛愬偓鍖栵紙纰抽吀閰愰叾锛�锛岄檺
鍒舵€у収(n猫i)鍒囬叾鍌寲姗熷埗锛岃倢鐞冭泲鐧藉偓鍖栨鍒�锛涢叾鐨勮(di脿o)绡€(ji茅)椤炲瀷锛氬垾妲�(g貌u)瑾�(di脿o)绡€(ji茅)锛屽崝(xi茅)鍚岃(di脿o)绡€(ji茅)锛�
鍚屽伐閰�锛屽叡鍍逛慨椋撅紝閰跺師婵€娲�锛涚硸锛屽柈绯栵紝澶氱硸锛岀硸鑻烽嵉锛岀硸铔嬬櫧锛屽嚌闆嗙礌锛涜剛
椤炶垏绱�(x矛)鑳炶啘锛氳剛鑲吀锛屼笁椤炶啘鑴�锛岀７鑴傝垏绯栬剛锛岃啘铔嬬櫧锛岃啘鐨勬祦鍕曟€�锛岀湡鏍哥敓鐗�
鍏�(n猫i)鑶滅郴绲�(t菕ng)锛涜啘瀛旈亾鑸囨车锛氫富鍕曢亱杓歌垏琚嫊閬嬭几锛屾绱氶亱杓革紙涔崇硸閫忛亷閰讹級锛岄亱杓�
鑸囪€楄兘锛孉BC 閬嬭几绯荤当(t菕ng)锛岄洟瀛愰€氶亾锛岀窗(x矛)鑳炶垏绱�(x矛)鑳為枔璺ㄩ洐鑶滈亱杓�锛涗俊铏熷偝灏�(d菐o)閫斿緫锛�
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鍚搁張鍙婂叾绲勬垚锛屾哀鍖栫７閰稿寲锛屽寲瀛�(xu茅)婊查€忓亣瑾�锛孉TP 鍚堟垚閰跺強鍚堟垚姗熷埗锛岀窔绮掗珨
鑶滀笂鐨勮唱(zh矛)瀛愯法鑶滅┛姊�锛屾哀鍖栭倓鍘熸姂鍒跺姂锛涚硸閰佃В锛岀硸鐣扮敓锛岀硸鍘熷悎鎴愰€斿緫锛屼笝閰�
閰告哀鍖栬劔缇�锛屾妾吀寰挵(hu谩n)锛屾垔绯栫７閰搁€斿緫锛屼箼閱涢吀寰挵(hu谩n)锛屽厜鍚堜綔鐢ㄤ腑鐨勫厜鍙嶆噳(y墨ng)鑸�
浜屾哀鍖栫⒊鐨勫悓鍖�锛涜剛鑲吀鐨勬哀鍖栭€斿緫锛屼箼閰拌紨閰� A 璺ㄨ啘绌挎锛岃紨閰� B12锛岄叜楂�锛�
鑴傝偑閰哥殑鍚堟垚锛屼箼閰板熀璺ㄨ啘閫斿緫锛屼箼閰拌紨閰� A 缇у寲閰�锛涙皑鍩洪吀鐨勫垎瑙ｄ唬璎濓紝姘�
鍩鸿綁(zhu菐n)绉婚叾锛屼笝姘ㄩ吀锛嶈憽钀勭硸寰挵(hu谩n)锛屽翱绱犲惊鐠�(hu谩n)閫斿緫锛屾皑鍩洪吀纰抽鏋朵唬璎�锛屾皑鍩洪吀浠�
璎濋叾缂轰箯鐧ワ紝姘ㄥ熀閰哥敓鐗╁悎鎴愮殑鍓嶉珨锛屼互姘ㄥ熀閰哥偤鍓嶉珨鍚堟垚鐨勭敓鍖栧姛鑳藉垎瀛�锛涙牳
鑻烽吀鍚堟垚鍓嶉珨锛屽槍鍛ゅ拰鍢у暥鐨勫悎鎴�锛孌NA 鐨勫崐淇濈暀銆佸崐涓嶉€ｇ簩(x霉)寰�(f霉)鍒�锛屽師鏍哥敓鐗�
DNA 鐨勫京(f霉)鍒堕亷绋嬶紝寰�(f霉)鍒跺弶锛孯NA 鍚堟垚锛屽弽缇╂牳閰稿強 RNA 骞叉摼鎶€琛�(sh霉)锛孯NA 鑱氬悎
閰讹紝杞�(zhu菐n)閷勬姂鍒�锛岃綁(zhu菐n)閷勫悗鍔犲伐锛涜泲鐧借唱(zh矛)鐨勫悎鎴愭椹�锛宼RNA 鍩烘湰绲�(ji茅)妲�(g貌u)锛屾皑鐢查叞 tRNA
鍚堟垚閰�锛屾牳绯栭珨鐨勭祫鎴�锛屾皑鍩洪吀鐨勬椿鍖�锛岃泲鐧藉悎鎴愭姂鍒跺姂锛岄伜鍌冲瘑纰硷紝铔嬬櫧鍚堟垚
鍚庡姞宸�锛屼俊铏熻偨锛屾硾绱�锛岀窗(x矛)鑳炰唬璎濈恫(w菐ng)绲�(lu貌)銆�
2. 鑰冭│瑕佹眰
鈶犵啛绶存帉鎻″熀鏈蹇点€佸熀鏈悊璜�锛�
鈶℃帉鎻″熀鏈殑瀵﹂鎶€鑳姐€佺敤鍩烘湰姒傚康鍜屽熀鏈悊璜栧垎鏋愬椹楃従(xi脿n)璞�锛�
鈶㈣兘澶犵郴绲�(t菕ng)閬嬬敤鍩虹(ch菙)鐭ヨ瓨锛屽垎鏋愯В姹鸿純寰�(f霉)闆滅殑鐢熷懡鍖栧(xu茅)鍟忛锛�
鈶ｆ帉鎻″悇绔犵瘈(ji茅)涔嬮枔鐭ヨ瓨榛炵殑鐩镐簰闂�(gu膩n)鑱�(li谩n)锛岃兘澶犲緸鏁撮珨瑙掑害浜嗚В鍕曟厠(t脿i)缍�(w菐ng)绲�(lu貌)绲�(ji茅)妲�(g貌u)锛岀啛鎮�
缍�(w菐ng)绲�(lu貌)绲�(ji茅)妲�(g貌u)涓瘡閮ㄥ垎鐨勯噸瑕佺煡璀樺収(n猫i)瀹广€�
3.椤屽瀷鍜屽垎鍊�
绺藉垎 150 鍒�锛屽～绌洪 30 鍒嗐€侀伕鎿囬 30 鍒�銆佸晱绛旈 90 鍒�
4.鍙冭€冩浉鐩�:
鐢熺墿鍖栧(xu茅) A 楂樼瓑鏁欒偛鍑虹増绀� 鐜嬮彙宸� 绗笁鐗�
鍏嶈铂(z茅)鑱叉槑锛氭湰鏂囩郴杞�(zhu菐n)杓夎嚜缍�(w菐ng)绲�(lu貌)锛屽鏈変镜鐘紝璜嬭伅(li谩n)绯绘垜鍊戠珛鍗冲埅闄�锛屽彟锛氭湰鏂囧儏浠ｈ〃浣滆€呭€嬩汉瑙€榛烇紝鑸囨湰缍�(w菐ng)绔欑劇闂�(gu膩n)銆傚叾鍘熷壍(chu脿ng)鎬т互鍙婃枃涓櫝杩版枃瀛楀拰鍏�(n猫i)瀹规湭缍�(j墨ng)鏈珯璀夊锛屽皪鏈枃浠ュ強鍏朵腑鍏ㄩ儴鎴栬€呴儴鍒嗗収(n猫i)瀹�銆佹枃瀛楃殑鐪熷鎬�銆佸畬鏁存€�銆佸強鏅傛€ф湰绔欎笉浣滀换浣曚繚璀夋垨鎵胯锛岃珛璁€鑰呭儏浣滃弮鑰�锛屽苟璜嬭嚜琛屾牳瀵︾浉闂�(gu膩n)鍏�(n猫i)瀹广€�
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鏂囩珷鎼滅储
鎮ㄧ従(xi脿n)鍦ㄧ殑浣嶇疆锛� 
