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鍙嬫儏鎻愮ず锛氭湰绔欐彁渚涘叏鍦�400澶氭墍楂樼瓑闄㈡牎鎷涙敹纰╁＋銆佸崥澹爺绌剁敓鍏ュ(xu茅)鑰冭│姝峰勾鑰冪爺鐪熼銆佽€冨崥鐪熼銆佺瓟妗�锛岄儴鍒嗗(xu茅)鏍℃洿鏂拌嚦2012骞�锛�2013骞�锛涘潎鎻愪緵鏀惰不(f猫i)涓嬭級銆� 涓嬭級娴佺▼锛� 鑰冪爺鐪熼 榛�(di菐n)鎿娾€�鑰冪爺瑭﹀嵎鈥濃€濅笅杓�; 鑰冨崥鐪熼 榛�(di菐n)鎿娾€�鑰冨崥瑭﹀嵎搴�鈥� 涓嬭級
2018 骞村寳浜静(n贸ng)瀛�(xu茅)闄㈡嫑鏀剁ⅸ澹爺绌剁敓鍏ュ(xu茅)鑰冭│澶х侗
鍒嗗瓙鐢熺墿瀛�(xu茅)鑰冭│澶х侗(灏堟キ(y猫)纰╁＋)
涓€銆佽姹傛帉鎻＄殑鍩烘湰鍏�(n猫i)瀹�
鎺屾彙鍒嗗瓙鐢熺墿瀛�(xu茅)鐨勫熀鏈悊璜栫煡璀�(sh铆)锛岀悊瑙ｅ寘鎷熀鍥犳蹇电殑婕旇畩鑸囩櫦(f膩)灞�銆丏NA 寰�(f霉)
鍒躲€丷NA 杞�(zhu菐n)閷�銆佽泲鐧借唱(zh矛)鐨勫悎鎴�銆佺湡鏍哥敓鐗╁拰鍘熸牳鐢熺墿鍩哄洜琛ㄩ仈(d谩)瑾�(di脿o)鎺�锛屼互鍙婂熀鍥犵獊
璁婅垏淇京(f霉)绛夋柟闈㈢殑鍏�(n猫i)瀹�銆傚湇绻炲熀鍥犻€欎竴涓荤窔锛屽灞ゆ銆佸瑙掑害鐞嗚В鍩哄洜寰�(f霉)鍒�銆佽〃
閬�(d谩)鍙婅(di脿o)鎺х殑闂�(gu膩n)绯�銆�
浜�銆佽│椤屾ā寮忓強鎵€鍗犳瘮渚�
鍒嗗瓙鐢熺墿瀛�(xu茅)鑰冭│绺藉垎 150 鍒�銆傞鍨嬪寘鎷細鍚嶈瑙ｉ噵锛堢磩鍗� 40 鍒嗭級銆侀伕鎿囬
锛堝柈閬�锛岀磩鍗� 30 鍒嗭級銆佸晱绛旈锛堢磩鍗� 50 鍒嗭級銆佹晿杩伴锛堢磩鍗� 30 鍒嗭級銆�
鑰冭│鏅�(sh铆)闁撶偤 180 鍒嗛悩銆傜瓟椤屾柟寮忥細闁夊嵎銆佺瓎瑭�銆�
涓夈€佽€冭│鍏�(n猫i)瀹�
1. 绶掕珫
鑰冭│鍏�(n猫i)瀹癸細鍒嗗瓙鐢熺墿瀛�(xu茅)鐨勬蹇�銆佸垎瀛愮敓鐗╁(xu茅)鐧�(f膩)灞曠啊鍙�銆佸垎瀛愮敓鐗╁(xu茅)鐮旂┒鐨勪富
瑕佸収(n猫i)瀹�銆佸垎瀛愮敓鐗╁(xu茅)鐨勬噳(y墨ng)鐢�銆�
鑰冭│鍩烘湰瑕佹眰锛氭帉鎻″垎瀛愮敓鐗╁(xu茅)鐨勬蹇点€�
2. 鍩哄洜姒傚康鐨勬紨璁婅垏鐧�(f膩)灞�
鑰冭│鍏�(n猫i)瀹癸細缍�(j墨ng)鍏哥殑鍩哄洜姒傚康锛屽熀鍥犵殑鍒嗗瓙绲�(ji茅)妲�(g貌u)锛屾牳閰稿垎瀛愮殑绌洪枔绲�(ji茅)妲�(g貌u)锛屽熀鍥�
姒傚康鐨勫妯ｆ€�銆�
鑰冭│鍩烘湰瑕佹眰锛氭帉鎻� DNA 鍜� RNA 鐨勫垎瀛愮祫鎴�锛屾牳鑻烽吀涔嬮枔鐨勯€ｆ帴鏂瑰紡銆侱NA
闆欒灪鏃嬬祼(ji茅)妲�(g貌u)鍙婄董鎸佺┅(w臎n)瀹氱殑鍥犵礌銆傛牳閰稿垎瀛愮殑绌洪枔绲�(ji茅)妲�(g貌u)銆傜啛鎮� DNA 鐨勮畩鎬�銆佸京(f霉)鎬у拰
鍒嗗瓙闆滀氦銆佸鑹叉晥鎳�(y墨ng)銆丏NA 鐨勮В閺堟韩搴︼紙Tm锛夌瓑姒傚康銆傛帉鎻℃柗瑁傚熀鍥�銆佽綁(zhu菐n)搴у瓙銆�
鍋囧熀鍥�銆侀噸鐤婂熀鍥�銆侀噸寰�(f霉)鍩哄洜绛夌殑瀹氱京鍜屽姛鑳�銆�
3. DNA 寰�(f霉)鍒�
鑰冭│鍏�(n猫i)瀹癸細DNA 寰�(f霉)鍒剁殑鍩烘湰鐗瑰緛锛岀湡鏍哥敓鐗� DNA 寰�(f霉)鍒剁殑鐗归粸(di菐n)锛孌NA 寰�(f霉)鍒剁殑绲�
姝�锛孌NA 寰�(f霉)鍒剁殑瑾�(di脿o)鎺�銆�
鑰冭│鍩烘湰瑕佹眰锛氭帉鎻″崐淇濈暀寰�(f霉)鍒剁殑姒傚康銆佺壒榛�(di菐n)锛屽弮鍔犲京(f霉)鍒剁殑鍚勭ó閰�銆佽泲鐧藉洜
瀛愮瓑鍦ㄥ京(f霉)鍒朵腑鐨勪綔鐢ㄣ€傚病宕庣墖娈�銆並lenow 鐗囨銆佺绮�銆佺绮掗叾銆侀€嗚綁(zhu菐n)閷勯叾鐨勬
蹇点€傜绮掕垏绔矑閰剁殑绲�(ji茅)妲�(g貌u)鐗归粸(di菐n)鑸囧姛鑳�锛岄€嗚綁(zhu菐n)閷勯叾鍌寲鐨勫弽鎳�(y墨ng)銆傜啛鎮� DNA 鍚堟垚閬庣▼锛�
鐪熸牳鐢熺墿 DNA 鑱氬悎閰�銆�
4. RNA 杞�(zhu菐n)閷�
鑰冭│鍏�(n猫i)瀹癸細杞�(zhu菐n)閷勭殑鍩烘湰姒傚康锛岃綁(zhu菐n)閷勮捣濮�锛岃綁(zhu菐n)閷勫欢浼革紝杞�(zhu菐n)閷勯亷绋嬬殑绲傛锛孯NA
鐨勫姞宸�銆�
鑰冭│鍩烘湰瑕佹眰锛氭帉鎻″京(f霉)鍒跺拰杞�(zhu菐n)閷勭殑鐣板悓榛�(di菐n)锛屽ぇ鑵告】鑿� RNA 鑱氬悎閰剁殑绲勬垚锛屾牳
蹇冮叾銆佸叏閰剁殑浣滅敤銆備笉灏嶇ū杞�(zhu菐n)閷勩€佺祼(ji茅)妲�(g貌u)鍩哄洜銆佹ā鏉块張銆佺法纰奸張銆佹湁鎰忕京閺�銆佸弽鎰�
缇╅張銆佸椤瓙銆佸収(n猫i)鍚瓙銆佹牳閰�銆佺祩姝㈠瓙绛夋蹇�銆傜啛鎮� RNA 绶ㄨ集鐨勬蹇�锛孯NA 鍚堟垚
閬庣▼锛岀湡鏍哥敓鐗� mRNA 鐨勫墠楂斿姞宸�銆傜湡鏍稿暉鍕�(d貌ng)瀛愮殑绋鍜屽姛鑳�锛岀湡鏍� RNA 鑱氬悎閰�锛�
鍩烘湰杞�(zhu菐n)閷勫洜瀛�锛岀壒鐣拌綁(zhu菐n)閷勫洜瀛愮殑绲�(ji茅)妲�(g貌u)鐗归粸(di菐n)銆�
5. 铔嬬櫧璩�(zh矛)鐨勭炕璀�
鑰冭│鍏�(n猫i)瀹癸細铔嬬櫧璩�(zh矛)鍚堟垚鐨勮鍌�锛岄伜鍌冲瘑纰煎強鍏剁啊骞讹紝铔嬬櫧璩�(zh矛)鐨勭炕璀�銆�
鑰冭│鍩烘湰瑕佹眰锛氭帉鎻″弮鑸囩炕璀殑鐗╄唱(zh矛)锛宮RNA銆乼RNA銆乺RNA 鐨勪綔鐢紝閬哄偝瀵嗙⒓
鐨勭壒鎬�锛屾皑鍩洪叞-tRNA 鍚堟垚閰剁殑浣滅敤銆傞伜鍌冲瘑纰�銆丼D 搴忓垪銆佷俊铏熻偨銆佸垎瀛愪即渚剁殑
姒傚康銆傜啛鎮夋牳铔嬬櫧楂斿惊鐠�(hu谩n)閬庣▼銆�
6. 鍩哄洜琛ㄩ仈(d谩)鐨勮(di脿o)鎺�
鑰冭│鍏�(n猫i)瀹癸細鍘熸牳鐢熺墿鍩哄洜琛ㄩ仈(d谩)瑾�(di脿o)鎺х殑鐞嗚珫鑸囨ā寮�锛屼笉鍒╃敓闀锋浠朵笅鐨勬噳(y墨ng)鎬ュ弽
鎳�(y墨ng)锛岃綁(zhu菐n)閷勫悗姘村钩鐨勮(di脿o)鎺э紝缈昏姘村钩涓婄殑瑾�(di脿o)鎺�锛岀炕璀悗鐨勫熀鍥犺〃閬�(d谩)瑾�(di脿o)鎺�锛岀湡鏍哥敓鐗�
鍩哄洜琛ㄩ仈(d谩)瑾�(di脿o)鎺х殑鐗规畩椤炲瀷銆�
鑰冭│鍩烘湰瑕佹眰锛氭帉鎻″熀鍥犺〃閬�(d谩)鐨勬檪(sh铆)闁撶壒鐣版€у拰绌洪枔鐗圭暟鎬�銆佺祫鎴愭€ц〃閬�(d谩)銆佺
瀹跺熀鍥�銆侀爢寮忎綔鐢ㄥ厓浠躲€佸弽寮忎綔鐢ㄥ洜瀛�銆佸暉鍕�(d貌ng)瀛�銆佸寮�(qi谩ng)瀛愩€佹矇榛樺瓙銆佹搷绺卞瓙銆佸弽
缇� RNA銆丷NA 骞叉摼鍜� microRNA 鐨勬蹇�銆傜湡鏍哥敓鐗╁熀鍥犵祼(ji茅)妲�(g貌u)鐗归粸(di菐n)銆傜啛鎮夊師鏍稿熀鍥犺綁(zhu菐n)
閷勮(di脿o)绡€(ji茅)鐗归粸(di菐n)锛屼钩绯栨搷绺卞瓙鐨勭祼(ji茅)妲�(g貌u)鍙婅(di脿o)绡€(ji茅)姗�(j墨)鍒躲€�
7. 鍩哄洜绐佽畩鐨勫垎瀛愭(j墨)鍒�
鑰冭│鍏�(n猫i)瀹癸細鍩哄洜绐佽畩锛岀敓鐗╅珨淇濊瓑绌�(w臎n)瀹氶伜鍌崇殑姗�(j墨)鍒�銆�
鑰冭│鍩烘湰瑕佹眰锛氱獊璁婄殑鍒嗗瓙椤炲瀷鍙� DNA 鎼嶅偡淇京(f霉)鐨勪富瑕佹柟寮忋€�
8. 甯歌鐨勫垎瀛愮敓鐗╁(xu茅)鐮旂┒鎶€琛�(sh霉)
鑰冭│鍏�(n猫i)瀹癸細鍩哄洜鍏嬮殕鎶€琛�(sh霉)鍜岀爺绌跺熀鍥犵祼(ji茅)妲�(g貌u)鍙婅〃閬�(d谩)鐨勫父鐢ㄦ妧琛�(sh霉)銆�
鑰冭│鍩烘湰瑕佹眰锛氭帉鎻″熀鍥犲厠闅嗘妧琛�(sh霉)鍜岀爺绌跺熀鍥犵祼(ji茅)妲�(g貌u)鍙婅〃閬�(d谩)鐨勫父鐢ㄦ妧琛�(sh霉)銆�
鍏嶈铂(z茅)鑱叉槑锛氭湰鏂囩郴杞�(zhu菐n)杓夎嚜缍�(w菐ng)绲�(lu貌)锛屽鏈変镜鐘�锛岃珛鑱�(li谩n)绯绘垜鍊戠珛鍗冲埅闄わ紝鍙︼細鏈枃鍍呬唬琛ㄤ綔鑰呭€�(g猫)浜鸿榛�(di菐n)锛岃垏鏈恫(w菐ng)绔欑劇闂�(gu膩n)銆傚叾鍘熷壍(chu脿ng)鎬т互鍙婃枃涓櫝杩版枃瀛楀拰鍏�(n猫i)瀹规湭缍�(j墨ng)鏈珯璀夊(sh铆)锛屽皪鏈枃浠ュ強鍏朵腑鍏ㄩ儴鎴栬€呴儴鍒嗗収(n猫i)瀹�銆佹枃瀛楃殑鐪熷(sh铆)鎬с€佸畬鏁存€�銆佸強鏅�(sh铆)鎬ф湰绔欎笉浣滀换浣曚繚璀夋垨鎵胯锛岃珛璁€鑰呭儏浣滃弮鑰�锛屽苟璜嬭嚜琛屾牳瀵�(sh铆)鐩搁棞(gu膩n)鍏�(n猫i)瀹广€�
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鏂囩珷鎼滅储
鎮ㄧ従(xi脿n)鍦ㄧ殑浣嶇疆锛� 
